Clinical trials: Tooth Disorder
Pain
Acetaminophen/Naproxen Sodium Dose Ranging Study
Study assessing the relative efficacy of five strengths of a fixed combination of acetaminophen and naproxen sodium is being investigated to help inform selection of dose(s) for further development and to evaluate the safety of a…
- Trial name
- NCT04447040
- Testing
- Acetaminophen/naproxen sodium Dose A, Acetaminophen/naproxen sodium Dose B, Acetaminophen/naproxen sodium Dose C
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division
Tooth Erosion, Teeth Erosion Due to Vomiting
Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental Erosion
Ultra-thin bonded posterior occlusal veneers represent a conservative alternative to traditional onlays and complete coverage crowns for the treatment of severe erosive lesions.
- Conditions
- Tooth Erosion, Teeth Erosion Due to Vomiting, Teeth Erosion Limited to the Enamel, Teeth Erosion Extending Into the Dentine
- Trial name
- UOVTDE (NCT03112278)
- Testing
- Ceramic ultrathin occlusal veneers, Composite resin ultrathin occlusal veneers
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Dentin Bridge, Pulpitis
Partial Pulpotomy on Caries Free Human Teeth
The purpose of this study is to compare the human pulp response to partial pulpotomy using White ProRoot MTA or iRoot BP in the terms of dentinal bridge formation and inflammation.
- Trial name
- NCT01420718
- Testing
- MTA, iRoot BP
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Endodontic Disease, Pulp Canal Obliteration
Revascularisation of Autotransplanted Teeth
Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection Note: The study was registered on Clinicaltrials.gov after termination of study.
- Trial name
- NCT05267249
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Graz
Malocclusion
Salivary Stress Markers Associated With Malocclusion Severity
The aim of this observational study is to evaluate the relationship between the severity of orthodontic malocclusion and psychophysiological stress levels in individuals aged 12 to 18 years.
- Trial name
- NCT07116317
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Pulp Therapy, Pulpitis - Irreversible
Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp
Preserving primary teeth until their normal exfoliation time is crucial for maintaining the child's normal function, esthetics, arch integrity, and correct eruption of permanent successors.
- Conditions
- Pulp Therapy, Pulpitis - Irreversible, Pulp Necrosis
- Trial name
- NCT07230717
- Testing
- Pulpotomy, Pulpectomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Caries
Clinical Evaluation of Nanoionomer Filling in Primary Teeth
This clinical trial was performed to evaluate the nano-filled resin modified glass ionomer (RMGI) -with a brand name of "Ketac Nano"- as a filling material for the treatment of caries in primary teeth.
- Trial name
- CENFPT (NCT02093091)
- Testing
- Dental caries was removed from primary molars and was filled with the recent filling material; Ketac Nano., Dental caries was removed from primary molars and was filled with the conventional filling material;Vitremer
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Tanta University
Impacted Third Molar Tooth, Tooth Extraction Status Nos
Clinical Validation of a Novel Classification for Predicting Surgical Complexity in Mandibular Wisdom Teeth Surgery
The study evaluates and validates a new classification proposed by Juodzbalys and Daugela in 2013 predicting the complexity of impacted mandibular third molars surgical extraction, comparing it with other two, scientifically…
- Trial name
- NCT02519426
- Testing
- Mandibular third molar surgery
- Where
- 2 sites in Italy, Lithuania
- Volunteers
- 110 people
- Sponsor
- Lithuanian University of Health Sciences
Surgical Incision, Malocclusion
Efficacy of Piezosurgey Corticotomy (a Minimally Invasive Surgical Technique) in Accelerating Orthodontic Alignment
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e.
- Trial name
- NCT02977221
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Molar Incisor Hypomineralization
Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH. In Vitro Study and In Situ Randomized Double-Blind Placebo Clinical Trial.
In child patients with molar incisor hypo mineralization, Will Vitamin D mouth wash offer more success for patients with MIH as regards better MIH TNI index, decrease plaque accumulation, more gingival health and less bleeding on…
- Trial name
- NCT06515548
- Testing
- Vitamin D3 mouth wash
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypominerlization (MIH) Among a Group of Egyptian Children
To determine the Prevalence of MIH in a group of Egyptian children attending the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University.
- Trial name
- MIH (NCT03498209)
- Volunteers
- 100 people
- Sponsor
- Cairo University
Dental Caries
Dietary Analysis for Caries Prevention in Children Using a Computer Software
Children will be recruited from the pediatric dentistry clinic of Marquette University at their first or recall appointment and will be asked to fill a questionnaire regarding their dietary habits.
- Trial name
- NCT02375763
- Testing
- Software instruction
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marquette University
Dental Caries, Dental Fluoroses
Iowa Fluoride Study/Iowa Bone Development Study
A cohort of newborns was recruited for the Iowa Fluoride Study from 1992-95 to assess the complex relationships among fluoride intakes, fluoride exposures, dental fluorosis, and dental caries.
- Conditions
- Dental Caries, Dental Fluoroses, Bone Density
- Trial name
- (IFS/IBDS) (NCT03547128)
- Volunteers
- 1,882 people, healthy volunteers welcome
- Sponsor
- Steven M Levy
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Molar Incisor Hypomineralization
Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH
MIH is a prevalent developmental defect which has a negative impact on children's OHRQoL, especially when incisor opacities are present.
- Trial name
- NCT05727475
- Testing
- Minimal invasive restorative treatment, Fluoride gel application
- Where
- Jordan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Irregular Teeth
Comparison of the Clinical Efficacy of the Lingual Brackets and Labial Brackets in the Leveling Phase
This aim study aims to compare clinical effectiveness of customized lingual brackets and conventional labial brackets in alignment period in a sample of Class I malocclusion patients treated on a nonextraction basis.
- Trial name
- NCT04357067
- Testing
- Lingual brackets, Labial brackets
- Volunteers
- 20 people
- Sponsor
- Aydin Adnan Menderes University
Malocclusion
A RCT to Compare OHRQoL Outcome for SLB and CB
The objective of this prospective study is to compare these two treatments (conventional brackets v.s. self-ligating brackets) in malocclusion to determine which treatment will provide the better oral health related quality of…
- Trial name
- NCT02084277
- Testing
- Self-ligating brackets (SLB), Conventional brackets (CB)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Mackay Memorial Hospital
Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy
Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study
The objective of the ActiLiège Next study is to collect longitudinal data from patients and control subjects using a wearable magneto-inertial device.
- Conditions
- Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy, Myotonic Dystrophy 1, Charcot-Marie-Tooth
- Trial name
- NCT05982119
- Testing
- ActiMyo/Syde
- Where
- 8 sites in Belgium, Czechia and 5 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Dental Caries, Dental Atraumatic Restorative Treatment
Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments
The present study aims evaluate the oral health conditions of schoolchildren and its relation to growth, development and well-being.
- Conditions
- Dental Caries, Dental Atraumatic Restorative Treatment, Oral Health
- Trial name
- NCT02754466
- Testing
- Subjective vs objective criteria in selective excavation, Glass-ionomer vs Bulk fill composites in the ART approach
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- University of Brasilia
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
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