Clinical trials: Trachea Diseases
Tracheo Esophageal Fistula, Congenital Diaphragmatic Hernia
Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during…
- Trial name
- NCT04507295
- Testing
- cerebral oximetry ( INVOS 5100 )
- Volunteers
- 30 people
- Sponsor
- Cairo University
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Tracheal Diseases
Laryngo-Tracheal Tissue-Engineered Clinical Transplantation
The proposed protocol will involve the replacement of the trachea using a synthetic bioengineered scaffold seeded with autologous mononuclear cells as an intraoperative solution for patients with with benign and malignant…
- Trial name
- NCT01997437
- Testing
- Stem-cell seeded bioartificial tracheal scaffold
- Where
- Russia
- Volunteers
- 6 people
- Sponsor
- Kuban State Medical University
Tracheo Esophageal Fistula
Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula Repair
Today Endoscopic repair of recurrent Tracheesophageal fistula (TEF) is a safe procedure. Using Trichlosiacetic acid 50% (TCA) for endoscopic aplication of the fistula was reported with a good results ( 4 cases).
- Trial name
- NCT01287312
- Testing
- Endoscopic repair of recurrent TEF by trichloroacetic acid aplications
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Esophageal Diseases
Post Market Clinical Study - Evolution® Esophageal Stent Systems, Europe: Fully and Partially Covered
The aim of this post-market clinical follow-up study is to evaluate the continued safety and performance of the marketed Evolution® Esophageal Stent System (Partially- and Fully Covered).
- Trial name
- NCT05182255
- Testing
- Evolution® Esophageal Stent Systems, Europe: Fully and Partially Covered
- Where
- 5 sites in Germany, Spain and 1 more
- Volunteers
- 127 people
- Sponsor
- Cook Research Incorporated
Tracheobronchomalacia
Bioresorbable Airway Splint Pivotal Clinical Trial
The purpose of this study is to learn if a three-dimensional (3D) printed airway splint device made to hold open a collapsing airway is a safe and effective treatment of Tracheobronchomalacia (TBM) in children.
- Trial name
- NCT06406452
- Testing
- Bioresorbable Tracheobronchial Splint
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Tracheal Intubation
Validation of Supra-Sternal Tube-Tip Palpation
Background: The intra-tracheal intubation of a patient is a most delicate medical procedure performed under often life-threatening conditions in in- and out-of-hospital acute care medicine.
- Trial name
- SSTTP (NCT00690508)
- Testing
- Supra-Sternal Tube-Tip Palpation (SSTTP)
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Ottawa
Tracheo-Esophageal Fistula with Atresia of Esophagus
Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula
This study aims to look at babies having a primary or delayed primary oesophageal repair for OA with dTOF to evaluate if using Indocyanine green (ICG) and near infrared fluorescence (NIRF) can decrease the rates of anastomotic…
- Trial name
- iTOF (NCT05735964)
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Tracheal Stenosis, Airway Disease
Endotracheal Dilator to Improve Oxygenation
The purpose of the study is to prospectively assess the use of a modified tracheal balloon dilator in children (<13 years old) with subglottic or tracheal stenosis.
- Conditions
- Tracheal Stenosis, Airway Disease, Pediatric Respiratory Diseases
- Trial name
- EDITION2 (NCT03411928)
- Testing
- Tracheolator
- Where
- South Africa
- Volunteers
- 12 people
- Sponsor
- University of Cape Town
Double-Lumen Endotracheal Tube Placement
Effect of Head Turn on Double-Lumen Tube Alignment
This study evaluated how simple external airway maneuvers affect the alignment of the left main bronchus during placement of a left-sided double-lumen endotracheal tube.
- Trial name
- NCT07755722
- Testing
- Right Tracheal Displacement, Right Head Turn Maneuver, Left Head Turn Maneuver
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
Tracheo Esophageal Fistula
Outcome Predictors of Trachea-esophageal Fistula
In the present study, the investigator aim to evaluate the prevalence, factors affecting outcome and the outcome of neonates with tracheoesophageal fistula.
- Trial name
- NCT05847101
- Testing
- Tracheoesophageal fistula repair
- Volunteers
- 100 people
- Sponsor
- Assiut University
Airway Disease
Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy
Introduction: The non-invasive ventilation (NIV) of continuous nasopharyngeal O2 with intermittent close/open nose and abdomen compression (PO2-NC-AC) can provide effective oxygenation, ventilation and circulation.
- Trial name
- NCT03666403
- Testing
- NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula
Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery
The study is primarily a descriptive study examining the physiological, ventilatory, surgical, and recovery effects of patients ≤ 6 months of age who undergo thoracoscopic surgery and to determine the accuracy of transcutaneous…
- Conditions
- Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula, Esophageal Atresia
- Trial name
- NCT02033772
- Testing
- Thoracoscopic surgery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Arlyne Thung
Tracheoesophageal Fistula, Esophageal Atresia With Tracheo-esophageal Fistula
Camera-based Endoscopy Allows Spontaneous Breathing Diagnostic Management in Neonates With Tracheoesophageal Fistula
The investigators aim to compare rigid tracheoscopy versus flexible tracheo-video-endoscopy in neonates requiring diagnostic assessment before undergoing a congenital tracheoesophageal fistula repair.
- Trial name
- CBESB (NCT07687628)
- Testing
- tracheoscopy performed with rigid optical tracheoscopy, flexible video endoscopy of trachea
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Papa Giovanni XXIII Hospital
Tracheo Esophageal Fistula
Inverse Ratio Ventilation in Neonatal Open Repair of Tracheoesophageal Fistula.
Background and Objectives: Maintaining oxygenation during neonatal open repair of esophageal atresia is difficult. Inverse ratio ventilation can be used during one lung ventilation (OLV) to improve the oxygenation and lung…
- Trial name
- NCT05150600
- Testing
- Inverse Ratio Ventilation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Tracheobronchomalacia
The Effect of Bethanechol on Tracheobronchomalacia
The primary aim of this study is to determine if work of breathing estimated using swing Edi will be improved following initiation of bethanechol in infants with tracheobronchomalacia.
- Trial name
- NCT05299008
- Testing
- Bethanechol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Laryngeal Cancer, Hypopharynx Cancer
A Novel Modified Tracheo-Esophageal Voice Prosthesis for Total Laryngectomy Patients
This study is being conducted at Healthcare Global Enterprises Ltd to evaluate the role of a novel Tracheo-Esophageal voice Prosthesis for total laryngectomy +/- partial pharyngectomy patients.
- Trial name
- TEP (NCT03039465)
- Testing
- Modified Trans-Esophageal Prosthesis
- Where
- India
- Volunteers
- 50 people
- Sponsor
- HealthCare Global Enterprise Ltd.
Tracheomalacia
Dynamic Airway CT is Diagnostic for Tracheomalacia in Children
The purpose of this pilot interventional study is to evaluate the use of Dynamic Airway Computed Tomography (DA-CT) for diagnosis of tracheomalacia in children 0-18 years for whom flexible bronchoscopy has been performed.
- Trial name
- NCT06028646
- Testing
- Dynamic Airway CT scan (DA-CT)
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Tracheal Stenosis
Challenges and Management of Post-intubation Tracheal Stenosis
Management of a "difficult airway" remains one of the most relevant and challenging tasks for anesthesiologists and pulmonary physicians.
- Trial name
- NCT06061380
- Testing
- no intervation taken
- Where
- Ethiopia
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Wollo University