Clinical trials: Tracheal Intubation in ICU
Respiratory Distress Syndrome in Premature Infant
Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam
Preterm babies often have trouble breathing because their lungs are not fully developed. This condition is called respiratory distress syndrome (RDS). A medicine called surfactant helps their lungs open up and work better.
- Trial name
- NEOSURF (NCT07098910)
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - Extubation (INSURE)
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Intubation Complication
Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study
The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce…
- Trial name
- SMART PICU (NCT06085326)
- Testing
- Smart Checklist
- Where
- 6 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Children's Hospital of Philadelphia
Cuff Overinflation, Cuff Underinflation
Cuff Pressure Regulation Apparatus for Tracheal Intubation in Children
Despite the expert recommendation about rigorous monitoring of tracheal cuff pressure using a continuous or intermittent technique, cuff underinflation and overinflation are common increasing the risk of microinhalation and…
- Trial name
- CPRATIC-2 (NCT04413318)
- Testing
- Electronic device (VBM©), Pneumatic device (Nosten©)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nosocomial Pneumonia, Healthcare-Associated Pneumonia
Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients
Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease incidence of pneumonia in patients undergoing open…
- Conditions
- Nosocomial Pneumonia, Healthcare-Associated Pneumonia, Aspiration Pneumonia, Ventilator-Associated Pneumonia
- Trial name
- NCT00610324
- Testing
- Chlorhexidine gluconate, Potassium permanganate
- Where
- India
- Volunteers
- 512 people
- Sponsor
- King Edward Memorial Hospital
Pain, Analgesia
EUROpean Pain Audit In Neonates
EUROPAIN Survey is an epidemiological study aimed at assessing current clinical practices regarding the use of sedative and analgesic drugs in newborns admitted to NICUs or PICUs in different countries in Europe.
- Conditions
- Pain, Analgesia, Sedation, Intesive Care
- Trial name
- EUROPAINsurvey (NCT01694745)
- Where
- 242 sites in Austria, Belgium and 16 more
- Volunteers
- 6,489 people
- Sponsor
- Hôpital Armand Trousseau
Videolaryngoscopy, Intensive Care Unit Syndrome
Awake Tracheal Intubation in Critical Care Patients
Tracheal intubation in critical care is a high-risk procedure requiring significant expertise and airway strategy modifications, such as awake intubation with video laryngoscope or flexible endoscope intubation.
- Trial name
- Awake (NCT05802316)
- Testing
- tracheal intubation using videolaryngoscope with a hyperangulated blade or standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Johannes Gutenberg University Mainz
Failed or Difficult Intubation, Sequela, Intubation; Difficult
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
- Trial name
- NEAR4KIDs (NCT02493478)
- Where
- 87 sites in United States, Australia and 9 more
- Volunteers
- 150,000 people
- Sponsor
- Children's Hospital of Philadelphia