Clinical trials: Tracheal Intubation in ICU
Mucosal Wound, Mucosal Erosion
The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries
Intensive care units (ICUs) are care centers equipped with a wide range of technological tools and devices used to provide the highest level of care to individuals whose lives are at risk, requiring a multidisciplinary team…
- Conditions
- Mucosal Wound, Mucosal Erosion, Mucosal Irritation, Endotracheal Intubation Fixation
- Trial name
- PreventionMMPI (NCT07390162)
- Testing
- Changes in the frequency of endotracheal tube repositioning
- Volunteers
- 230 people
- Sponsor
- Hacettepe University
Intubation Complication
Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study
The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce…
- Trial name
- SMART PICU (NCT06085326)
- Testing
- Smart Checklist
- Where
- 6 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Children's Hospital of Philadelphia
Patients Requiring Endotracheal Intubation
Intubated ICU Patients
The purpose of this research study is to determine how cell changes during endotracheal intubation and artificial lung ventilation affect lung inflammation.
- Trial name
- NCT02171091
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Intensive Care Unit Syndrome, Tracheal Intubation Morbidity
French and EuRopean Outcome Registry in Intensive Care Unit
The purpose of this study is to identify within a cohort of ICU patients admitted for severe illness those who are at risk of death in the year following the discharge from ICU.
- Trial name
- FROG-ICU (NCT01367093)
- Where
- 2 sites in France
- Volunteers
- 2,137 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Insufficiency
Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients
This is a phase III trial comparing early tracheotomy versus prolonged endotracheal intubation in intensive care unit patients needing prolonged ventilatory support.
- Trial name
- NCT00127621
- Testing
- early tracheotomy, prolonged endotracheal intubation
- Where
- France
- Volunteers
- 468 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
COVID-19 Acute Respiratory Distress Syndrome
Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients
In this comparative prospective study, we aim to compare the classic Macintosh laryngoscope and the Mac Grath videolaryncoscope in ICU covid 19 patients recruiting intubation and invasive mechanical ventilation.
- Trial name
- NCT04956913
- Testing
- Mac Grath, Macintosh
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Emergency Tracheal Intubation in Critically Ill Patients
Ciprofol Versus Propofol for Tracheal Intubation in ICU
The physiological reserves of critically ill patients are relatively low, and the risk of complications related to tracheal intubation in the ICU is higher than in the operating room.
- Trial name
- NCT06344949
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Intensive Care
Development and Validation of a Mouth Assessment Tool for Orally Intubated Patients in Intensive Care Unit)
Oro-tracheal Intubation uses oro-pharyngeal lesions, impacting on the length and quality of the patient's hospital stay. There are no oral status assessment tools specifically adapted to orally intubated patients.
- Trial name
- MAT (NCT06628440)
- Testing
- oral condition assessment tool
- Where
- 10 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
Critically Ill Adults in the ICU, Requiring Endotracheal Intubation
Effect of a FLUid Bolus or a Low Dose VAsopressor Infusion on Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation.
Tracheal intubation, which is one of the most commonly performed procedures in the care of critically ill patients in intensive care unit, is associated with a high incidence of complications.
- Trial name
- FLUVA (NCT05318066)
- Testing
- Ringer Lactate and Norepinephrine infusion
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Tata Memorial Centre
Intensive Care Unit
Non-invasive Early Oxygen- Reserve-index (ORI) Determination to Prevent Hypoxaemia During Endotracheal Intubation
The purpose of this study is to determine whether ORI monitoring increases the lowest oxygen saturation level during the interval between the first laryngoscopy (defined as introduction of the laryngoscope into the mouth) and the…
- Trial name
- NESOI-2 (NCT05867875)
- Testing
- Unblinded ORI values, Blinded ORI values
- Where
- 21 sites in France
- Volunteers
- 950 people
- Sponsor
- Nantes University Hospital
Nosocomial Pneumonia, Healthcare-Associated Pneumonia
Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients
Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease incidence of pneumonia in patients undergoing open…
- Conditions
- Nosocomial Pneumonia, Healthcare-Associated Pneumonia, Aspiration Pneumonia, Ventilator-Associated Pneumonia
- Trial name
- NCT00610324
- Testing
- Chlorhexidine gluconate, Potassium permanganate
- Where
- India
- Volunteers
- 512 people
- Sponsor
- King Edward Memorial Hospital
Arterial Line, Consent of Patients
Hemodynamic and Biological Evaluations During Reventilation Collapse in ICU
Prospective, observational clinical multicentric study in ICU; during the period surrounding the orotracheal intubation.
- Conditions
- Arterial Line, Consent of Patients, Adult Patients, Tracheal Intubation in ICU
- Trial name
- REVECOL (NCT01785654)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intratracheal Intubation in Critical Care
McGrath Mac Videolaryngoscope Versus Macintosh Laryngoscope for Orotracheal Intubation in Critical Care Unit
The aim of this study is to demonstrate that the rate of successful orotracheal intubation at first laryngoscopy will be higher in patients intubated with McGrath Mac videolaryngoscope compared to patients intubated with…
- Trial name
- MACMAN (NCT02413723)
- Testing
- Videolaryngoscope, Standard laryngoscope
- Where
- 7 sites in France
- Volunteers
- 371 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Critically Ill Patients
Esketamine Induction Intubation in ICU Patients.
Intubation in the intensive care unit (ICU) is usually an emergency. Pathophysiological changes such as shock, respiratory failure, and metabolic acidosis in critically ill patients can significantly increase the incidence of…
- Trial name
- NCT05464979
- Testing
- Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato], midazolam, fentanyl
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Hypotension
Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation
Collect hemodynamic data, such as heart rate, blood pressure, and cardiac output to help understand the effect of pre and post intubation.
- Trial name
- NCT03525743
- Testing
- NICOM (Non invasive cardiac output monitor)
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Mechanical Ventilation, Nonverbal Communication
Brain Computer Interface for Communication in Ventilated Patients
Objectives: Specific Aim 1: To demonstrate the feasibility of using a Steady State Visual Evoked Potential (SSVEP) based Brain Computer Interface (BCI) device to facilitate communication of common patient needs in alert…
- Conditions
- Mechanical Ventilation, Nonverbal Communication, Intratracheal Intubation, Critical Illness
- Trial name
- NCT02791425
- Testing
- Brain Computer Interface (BCI) device, Communication picture board
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Failed or Difficult Intubation, Sequela, Intubation; Difficult
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
- Trial name
- NEAR4KIDs (NCT02493478)
- Where
- 87 sites in United States, Australia and 9 more
- Volunteers
- 150,000 people
- Sponsor
- Children's Hospital of Philadelphia
Oral Mucosal Pressure Injury
Oral Mucosal Pressure Injury in ICU Patients With Oral Tracheal Intubation
In this study, based on the conceptual framework of Pressure Injurie development, the risk factors for pressure injury in critically ill patients provided by the latest guidelines, and combined with the current relevant studies…
- Trial name
- NCT05882539
- Testing
- endotracheal tube material,Bite block Material
- Where
- China
- Volunteers
- 471 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intubation Intraesophageal
Non Invasive Ventilation Combined to High Flow Nasal Cannula Oxygen for Preoxygenation of Hypoxemic ICU Patients
Tracheal intubation is a challenging procedure in Intensive Care Unit (ICU), associated with severe life threatening complications. To decrease these complications, preoxygenation is recommended.
- Trial name
- OPTINIV (NCT02530957)
- Testing
- Non invasive ventilation + High flow nasal cannula oxygen, Non invasive ventilation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Intubation; Difficult or Failed
Comparison Between C-mac,Pentax Video Laryngoscopes and Machintosh Laryngoscope
Asses and compare the practility and the level of difficulty in using C-mac and pentax video-laryngoscopes or the traditional Macintoch laryngoscope in intubation in ICU patients while wearing face shield
- Trial name
- NCT07255235
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Minia University