Clinical trials: Transplant Complication
Implant Complication
Modified Shell Technique Versus Onlay Bone Graft in Anterior Maxilla
Amount of bone volume and (width and height): Will be measured using linear measurements from CBCT after 6 month from implant insertion.
- Trial name
- NCT03663439
- Testing
- modified shell technique
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immune Tolerance, Liver Transplant; Complications
Immune Tolerance After Pediatric Liver Transplantation
Immunosuppressive (IS) agents are effective treatment to avoid acute or chronic rejection after pediatric liver transplantation.
- Trial name
- NCT05501301
- Testing
- IS weaning off
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Kidney Failure, Chronic, Peritoneal Dialysis Complication
International (Pediatric) Peritoneal Biobank
Within few years the peritoneal membrane of adult peritoneal dialysis (PD) patients undergoes substantial morphological transformation, including progressive fibrosis, vasculopathy and neoangiogenesis.
- Conditions
- Kidney Failure, Chronic, Peritoneal Dialysis Complication, Transplantation, Healthy
- Trial name
- NCT01893710
- Testing
- biopsy sampling
- Where
- 26 sites in United States, Austria and 13 more
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Renal Transplantation, Chronic Kidney Insufficiency
Urinary Biomarkers in Paediatric Kidney Transplantation (pKTx)
This study aims to test and validate the panel of study urinary biomarker to assess whether (1) reference values differ between paediatric renal transplant patients, patients with chronic kidney disease stage IV and V (CKD IV-V)…
- Conditions
- Renal Transplantation, Chronic Kidney Insufficiency, Healthy Controls
- Trial name
- NCT05208788
- Testing
- Biomarker test
- Where
- Germany
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Solid Organ Transplantation, Pregnancy
Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant, Transplantlines Next Generation
Background Pregnancy after all types of solid organ transplantation (SOT) is possible, although these have higher risk of pregnancy complications for mother and child, such as preeclampsia and preterm birth.
- Conditions
- Solid Organ Transplantation, Pregnancy, Long-term Follow-up, Kidney Transplant
- Trial name
- NCT07291258
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Displacement of Other Bone Devices, Implants and Grafts, Mechanical Complication of Other Bone Devices, Implants and Grafts
Influence of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants
The purpose of this study is to evaluate the effect of Low level laser therapy on stability and displacement of orthodontic miniscrew implants using two different force application protocols.
- Trial name
- NCT02891499
- Testing
- Low-level laser therapy, Mediate force application
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Nephrotic Syndrome
Multitarget Strategy for Primary Podocytopathies
The goal of this clinical trial is to verify whether a cell culture system can be used to evaluate the presence of a factor capable of causing proteinuria in the serum of patients with primary podocytopathies.
- Trial name
- PODO-TARGET (NCT06718894)
- Testing
- Biologic fluid sampling
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
End Stage Renal Disease, Transplantation
Live Kidney Donor Study - Cross-Sectional and Historical Cohort Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Trial name
- NCT00951977
- Where
- 3 sites in United States
- Volunteers
- 7,029 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Kidney; Complications, Allograft, Transplantation Infection
The Role of B Cells in Kidney Allograft Dysfunction
The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation.
- Trial name
- NCT02294032
- Testing
- Immunosuppressive Agents
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Liver Transplant; Complications, HLA Antigens
The Relationship Between HLA Tissue Compatibility and Biliary Complications in Patients With Liver Transplantation
Liver transplantation has become the accepted treatment option for advanced liver failure in recent years. In addition to the increase in the number of centers performing transplant and the decrease in complication rates…
- Trial name
- NCT04885582
- Testing
- HLA antigen results
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Cardiovascular Complications, Leukemia
Study of Metabolic Syndrome in Adolescent and Young Adult Survivors of Childhood Leukemia Who Have Undergone Stem Cell Transplant
RATIONALE: Gathering information about how often metabolic syndrome occurs in young survivors of childhood leukemia who have undergone stem cell transplant may help doctors learn more about the disease and the long-term effects…
- Conditions
- Cardiovascular Complications, Leukemia, Long-term Effects Secondary to Cancer Therapy in Children, Metabolic Syndrome
- Trial name
- NCT00920842
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Kidney Disease, Dialysis
The Impact of the Human Papilloma Virus in Pediatric Chronic Kidney Disease, Dialysis, and Transplant Patients
The proposed study is a pilot study and a first step towards developing an optimized HPV vaccination strategy for girls who have CKD, or are on dialysis or have a kidney transplant.
- Trial name
- NCT00767897
- Testing
- Human Papillomavirus Vaccine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Indiana University
Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately
Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Tacrolimus is the most commonly used immunosuppressant for preventing and treating rejection after liver transplantation. However, its treatment window is narrow, the pharmacokinetic individual differences are large, routine dose…
- Conditions
- Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately, Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients, According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted
- Trial name
- NCT06319391
- Testing
- CYP3A5*1*、CYP3A5*1*3, CYP3A5*3*3
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziqiang Li
Liver Transplant; Complications, Renal Complication of Procedure
Renal Outcomes Among Post Liver Transplantation Patients
To evaluate Renal outcomes among patients, post liver transplantation at Assiut university.
- Trial name
- NCT06123260
- Testing
- renal function tests
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postoperative Pain, Acute
Transversalis Fascia Plane Block for Iliac Bone Graft in Children
The purpose of this study is to determine which method is more effective in postoperative pain control in children undergoing iliac bone grafting for alveoloplasty under general anesthesia: ultrasound-guided transverse abdominal…
- Trial name
- NCT06403462
- Testing
- transversalis fascial plane block, transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Kidney Disease 5D, Chronic Kidney Disease 5T
Humoral and Cellular İmmune Response to SARS-CoV-2 mRNA BNT162b2 Vaccine in Children With Chronic Kidney Diseases
Coronavirus 2019 (COVID-19) infection is associated with higher morbidity and mortality in adult patients on dialysis, and kidney transplant recipients (KTRs).
- Trial name
- NCT05465863
- Testing
- SARS-CoV-2 mRNA BNT162b2 vaccine (Pfizer-BioNTech®)
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Liver Diseases, Liver Transplant; Complications
Design and Implementation of the Pediatric Liver Transplantation Biobank
The purpose of the pediatric liver transplant biobank is to systematically collect clinical specimens from pediatric end-stage liver disease.
- Conditions
- Liver Diseases, Liver Transplant; Complications, Pediatric ALL
- Trial name
- NCT04477967
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Complications of Organ Transplant Stem Cells Umbilical Cord
Treatment Protocol of Child SAA With the Injection of Mesenchymal Stem Cells（Umbilical Cord Derived）
Mesenchymal Stem Cells (MSC) is a non Hematopoietic Stem Cells (HSC) in adult bone marrow and takes part in the bone marrow microenvironment.
- Trial name
- MSC-SAA (NCT02218437)
- Testing
- MSC+ATG
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences