Clinical trials: Trauma Nervous System
Vestibular Disorder
Vestibular Treatment in Adolescents Following Sport Related Concussion
Each year, nearly 2 million children and adolescents have a sport-related concussion (SRC) in the U.S., but 57% of them do not receive appropriate clinical care following their injury.
- Trial name
- NCT03555370
- Testing
- Vestibular Exercise Intervention, Standard of Care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Gastric Cancer, Hepatic Carcinoma
Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025…
- Conditions
- Gastric Cancer, Hepatic Carcinoma, Pulmonary Carcinoma, Pancreatic Carcinoma
- Trial name
- NCT07359586
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Zhejiang University
Concussion, Post-concussion Syndrome
Aerobic Training for Management of Post-Concussion Syndrome in Adolescents
Sports-related concussions are common in adolescent-athletes. Prolonged recovery after concussion or post-concussion syndrome (PCS) is a public health problem.
- Conditions
- Concussion, Post-concussion Syndrome, Sports Injury
- Trial name
- NCT02035579
- Testing
- Aerobic Training Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Concussion
Vitamin Therapy in Concussion Management: A Randomized Control Trial
The purpose of this study is to assess the efficacy of vitamin therapy in concussion when compared to placebo with respect to multiple endpoints including symptom severity, cognitive performance on computer based…
- Trial name
- NCT02382679
- Testing
- Experimental: Vitamin Mixture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Mild Traumatic Brain Injury
New Protein Biomarkers and Technology for Improving Diagnosis and Outcome Prediction in Mild TBI
Mild traumatic brain injury(mTBI) is a common cause of consultation to the emergency rooms worldwide and is the most common form of traumatic brain injury.
- Trial name
- NCT06327776
- Testing
- Serum and saliva biomarkers
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Universitario 12 de Octubre
Shoulder Injuries, Pain, Postoperative
Battlefield Acupuncture Following Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to standard post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation…
- Conditions
- Shoulder Injuries, Pain, Postoperative, Acupuncture, Ear, Pain Management
- Trial name
- BFA (NCT04094246)
- Testing
- Battlefield Acupuncture, Standard post-surgical rehabilitation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Keller Army Community Hospital
Concussion, Brain, Mild Traumatic Brain Injury
Risk Stratification in Children With Concussion
This project will measure concussion symptoms, biological markers, and academic and social factors across the first year postconcussion to develop a model that enables early identification of and symptom management for children…
- Trial name
- RSiCC (NCT05825027)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Traumatic Brain Injury
The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT)
The TOPHR HIT trial is a clinical trial of patients experiencing blunt trauma who present with an injury to their head which makes them unconscios.
- Trial name
- TOPHR HIT (NCT01642524)
- Testing
- hypertonic saline mixed Dextran, Saline solution
- Volunteers
- 114 people
- Sponsor
- Sunnybrook Health Sciences Centre
Shoulder Pain, Tendinosis
The Morphometric Parameters of Shoulder and Supraspinatus Tendinosis
Supraspinatus tendinosis one of the most common pathologies of the musculoskeletal system.The aim of this study to investigate the relationship between supraspinatus tendinosis and shoulder morphology with magnetic resonance…
- Trial name
- NCT05132959
- Testing
- magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Alanya Alaaddin Keykubat University
Spinal Cord Injury
fMRI In Spinal Cord Injury Patient After Rehabilitation
The purpose of this study was to evaluate the potential reorganization in the sensorimotor cortex in spinal cord injury (SCI) patients after Body Weight Supported Treadmill Training (BWSTT) associated with conventional motor…
- Trial name
- NCT02074670
- Testing
- Treadmill gait training
- Where
- Brazil
- Volunteers
- 7 people
- Sponsor
- University of Nove de Julho
Postoperative Pain, Rotator Cuff Injuries
US-Guided Preemptive Brachial Plexus Blockade May Reduce Post-operative Pain: a Randomized Study
Intense e recurrent nociceptive stimulation, which occurs in the postoperatively, can trigger sensitization of the peripheral and central nociceptive pathway, leading to chronic pain.
- Trial name
- NCT04005534
- Testing
- Standard group, Preemptive group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Traumatic Brain Injury
Evaluation of Discriminating Power of Two Biomarkers in the Evaluation of Cerebral Lesions Due to Head Injuries in Infants and Children
Head injury is a frequent motive of consultation in paediatric emergency units and the first cause of mortality in infants of more than one year old in developped countries.
- Trial name
- TCOP100 (NCT02855034)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 167 people
- Sponsor
- University Hospital, Montpellier
Concussion, Mild, TBI (Traumatic Brain Injury)
Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment
mTBI is widely recognized as a major public health concern in the United States and worldwide. mTBI diagnosis remains a clinical challenge as no single test can diagnose every concussion.
- Conditions
- Concussion, Mild, TBI (Traumatic Brain Injury), Mild Traumatic Brain Injury
- Trial name
- NCT03265912
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- ElMindA Ltd
Sports Injuries, Concussion, Brain
AIM CONTROL and SWECON - Handball The SWEdish CONcussion Study in Elite Handball
Handball is reported to be top 5 in Europe when it comes to sports injuries. There are few studies based on player reported data, and earlier Swedish data is mainly based on data from Insurance ´companies and mostly acute…
- Conditions
- Sports Injuries, Concussion, Brain, Exposure, Psychological
- Trial name
- NCT04109677
- Where
- Sweden
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Spinal Cord Injury, Neuromodulation
Rehabilitation Combining Spatiotemporal Spinal Cord Stimulation and Real-time Triggering Exoskeleton After Spinal Cord Injury
Spinal cord injury (SCI) can be caused by trauma, inflammation, tumors, and other factors, often leading to issues such as impaired leg movement, abnormal sensation, and difficulties with bladder and bowel control.
- Conditions
- Spinal Cord Injury, Neuromodulation, Robot Assisted Gait Training
- Trial name
- SCS-EXS (NCT06881134)
- Testing
- SCS+EXS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Brain Injuries
Tranexamic Acid for Preventing Progressive Intracranial Haemorrhage in Traumatic Brain Injury
The study's objective is to evaluate the effectiveness and safety of tranexamic acid for adult patients with moderate to severe TBI.With the research question as "Does TXA reduce the incidence of progressive intracranial…
- Trial name
- NCT00755209
- Testing
- tranexamic acid
- Where
- Thailand
- Volunteers
- 238 people
- Sponsor
- Khon Kaen University
Concussion, Mild, Concussion; Eye
EYE-SYNC Concussion Classification Study
The purpose of this study is to determine the sensitivity and specificity of an aid in assessment of concussion based on eye-tracking, in comparison to a clinical reference standard appropriate for sport-related concussion…
- Conditions
- Concussion, Mild, Concussion; Eye, Concussion, Brain, Concussion, Severe
- Trial name
- NCT04381767
- Testing
- EYE-SYNC
- Where
- United States
- Volunteers
- 1,303 people
- Sponsor
- Sync-Think, Inc.
Brain Injury
Genotype Influence on Recovery After Traumatic Brain Injury
Genetic differences in response to brain injury may reasonably be expected to play a role in the initial consequences of traumatic brain injury and in the rate of recovery from such injury.
- Trial name
- NCT00018499
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Brain Injuries, Traumatic, Brain Injury Traumatic Moderate
A Prospective Outcome Study in Patients With Moderate to Severe Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of death, disability and cognitive impairment in young people worldwide. The majority of the traumatic deaths in developed countries results directly from lesions in the central…
- Conditions
- Brain Injuries, Traumatic, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe
- Trial name
- TBI-PRO (NCT03810222)
- Testing
- N/A (Observational Study)
- Where
- Italy
- Volunteers
- 225 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS