Clinical trials: Trauma and Stressor Related Disorder
Systemic Inflammatory Response Syndrome, Posttraumatic Stress Disorder
Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery
Hydrocortisone has been shown to improve the early outcome of high risk patients after cardiac surgery. A potential mechanism resulting in this effect may be its immunomodulatory action.
- Trial name
- NCT00490828
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Posttraumatic Stress Disorder
Stepped Care for Young Children After Trauma
The aim of this R34 study is to develop and test the feasibility of a Stepped Care intervention for young children with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01603563
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of South Florida
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Post-Traumatic Stress Disorder in Children, Post-traumatic Stress Disorder
Adaptation of the PCIP for Children Aged 6 to 11
This study will implement a brief Post-traumatic Stress Disorder (PTSD) intervention for children, the Primary Care Intervention for PTSD (PCIP) delivered through telehealth (computer or smartphone delivery), to 10 youth age 6-11…
- Trial name
- NCT05606172
- Testing
- Primary Care Intervention for PTSD (PCIP) Youth aged 6 -11, Waitlist Treatment as Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Grief
Adolescent Suicide Loss Survivors Grief Intervention Group
This study will provide evidence-based recommendations for designing interventions tailored to adolescents dealing with suicide loss.
- Trial name
- NCT07151092
- Testing
- Adolescent Grief Group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Stress Disorders, Post-Traumatic
A Ten-Week Study Evaluating The Effectiveness And Safety Of Zoloft In Children And Adolescents With A Diagnosis Of PTSD
To evaluate the safety and efficacy of sertraline compared to placebo in children and adolescents (6 to 17 years of age) who are outpatients with Posttraumatic Stress Disorder.
- Trial name
- NCT00150306
- Testing
- Zoloft (Sertraline)
- Where
- 23 sites in United States
- Volunteers
- 160 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stress Disorder
Guanfacine Extended Release and Mindfulness Skills Therapy
Teenagers are invited to take part voluntarily in a research study of a study drug known as guanfacine extended release (Intuniv™) and a type of psychotherapy called Mindfulness Skills Training which teaches people how to focus…
- Trial name
- NCT03258476
- Testing
- Guanfacine Extended Release, Mindfulness Skills Therapy
- Where
- United States
- Sponsor
- UConn Health
Concussion, Stress Disorders, Post-Traumatic
Concussion and Post Traumatic Stress in Traumatic Brain Injury
Mild brain injury or concussion affects about four million Americans each year. Some people recover completely while others, especially those with multiple concussions, develop chronic headaches, neurodegenerative diseases and…
- Trial name
- CAPIT (NCT02119533)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
PTSD, Depression
Arts and Movement Therapies for Trauma
The current goal of this project is to subjectively and objectively assess the efficacy of arts and movement interventions--including dance/movement therapy, art therapy and mindful yoga for youth and adults exposed to trauma…
- Conditions
- PTSD, Depression, Anxiety, Stress
- Trial name
- NCT03515564
- Testing
- Dance/Movement Therapy, Art Therapy, Mindful Yoga
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Wayne State University
PTSD - Post Traumatic Stress Disorder
Comparing the Effectiveness of Art and Sand-play in Reducing PTSD Among Refugee Children
Due to the political state of Syria, Jordan is experiencing a major increase in the number of Syrians seeking asylum each year, a quarter of which are children.
- Trial name
- NCT06984198
- Testing
- Sandplay Therapy, Art Therapy
- Where
- Jordan
- Volunteers
- 130 people
- Sponsor
- King Abdullah University Hospital
Autism Spectrum Disorder, PTSD and Trauma-related Symptoms
TF-CBT for Autistic Youth Pilot Implementation - Open Pilot
Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure.
- Conditions
- Autism Spectrum Disorder, PTSD and Trauma-related Symptoms, Autism, Trauma and Stressor Related Disorders
- Trial name
- NCT07420478
- Testing
- Trauma-Focused Cognitive Behavioral Therapy, modified for autistic youth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma
Psycho-education Program BLAME-LESS and It's Effect on Traumarelated Shame and Guilt
The primary objective of the BLAME-LESS study is to examine the effectiveness of an online psychoeducation program in reducing trauma-related feelings of shame and guilt in adolescents who experienced sexual or physical abuse .
- Trial name
- BLAME-LESS (NCT05987735)
- Testing
- BLAME-LESS
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Stress Disorders, Post Traumatic, Anxiety
Preventing Post-traumatic Stress in ICU Survivors: A Pilot Randomized Controlled Trial of ICU Diaries
The main objective of the study is to test the feasibility of the ICU diaries intervention in the ICU. The investigators do not have sufficient power to detect differences in the hypotheses below, but will use the present pilot…
- Conditions
- Stress Disorders, Post Traumatic, Anxiety, Depression, Quality of Life
- Trial name
- NCT02067559
- Testing
- ICU Diary, Psychoeducation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Manitoba
Stress Reaction; Acute
Racial Discrimination and Stress Response
The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or…
- Trial name
- NCT05820659
- Testing
- peer rejection task, conversation about peer rejection, and impossible puzzle task
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Depression, Anxiety, Post Traumatic Stress Disorder
Adaptation and Evaluation of the KEEP Model
This study capitalizes on an opportunity to formally evaluate local adaptations of "Keeping Foster and Kinship Parents Supported and Trained" (KEEP), an evidence-based foster parent intervention, to reduce mental health…
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Suicide and Self-harm, Externalizing Behavior
- Trial name
- NCT05816421
- Testing
- KEEP, Non-Affinity KEEP
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Oregon Social Learning Center
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Post Traumatic Stress Disorder, Anxiety
National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database
Trauma-informed treatment will improve emotional regulation and behavior.
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression, Conduct Disorder
- Trial name
- NCT01591694
- Where
- United States
- Volunteers
- 4,193 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Intervention Effectiveness, Practice-based Evidence
Strengthening Family Coping Resources Open Trials
Strengthening Families Coping Resources (SFCR) Open Trials completes the second stage of the National Institute on Drug Abuse's intervention development model by testing a new family, skills-based intervention involving pre-post…
- Conditions
- Intervention Effectiveness, Practice-based Evidence, Posttraumatic Stress Disorder
- Trial name
- SFCR (NCT01754610)
- Testing
- Strengthening Family Coping Resources (SFCR)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore