Clinical trials: Tumor Thrombus
Thrombosis, Deep Venous Thrombosis
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE).
- Conditions
- Thrombosis, Deep Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- GIVTE (NCT00660205)
- Where
- Denmark
- Volunteers
- 285 people
- Sponsor
- University of Aarhus
Acute Lymphoblastic Leukemia
Hemostasis During Asparaginase Treatment in Acute Lymphoblastic Leukemia(ALL)
Asparaginase is an important drug in the treatment of childhood leukemia. One of the rare but severe side effects to the treatment is thrombosis in or outside the central nervous system.
- Trial name
- NCT01094392
- Where
- 4 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- Aarhus University Hospital
Arterial Thromboembolism, Venous Thromboembolism
Long-term Active Surveillance Study for Oral Contraceptives (LASS)
The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.
- Conditions
- Arterial Thromboembolism, Venous Thromboembolism, Breast Cancer
- Trial name
- NCT00676065
- Where
- Germany
- Volunteers
- 58,303 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Tumor Thrombus
Role of Anticoagulation in the Management of Tumor Thrombus
The purpose of this study is to conduct a retrospective review of oncology patients with a diagnosis of any solid tumor and lymphoma to identify a cohort with radiographically reported tumor thrombus or tumor compression of…
- Trial name
- TUMOR THROMBUS (NCT07748234)
- Where
- United States
- Volunteers
- 1,900 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
HepatoCellular Carcinoma
Radiotherapy in Hepatocellular Carcinomas After Hepatectomy With Narrow Margin (<1 cm) or Portal Vein Thrombosis
Hepatocellular carcinoma (HCC) is one of ten leading cancer types worldwide and also in Asia, but the five-year relative survival rate is relatively quite low1-3.
- Trial name
- RHCC (NCT02309788)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Hepatic Artery Thrombosis, Hepatic Artery Stenosis
Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children
The goal of this observational study is to investigate the incidence, current management practices, and outcomes in pediatric patients with HAC after liver transplantation.
- Conditions
- Hepatic Artery Thrombosis, Hepatic Artery Stenosis, Pediatric ALL, Liver Transplant; Complications
- Trial name
- HEPATIC (NCT05818644)
- Where
- Netherlands
- Volunteers
- 583 people
- Sponsor
- University Medical Center Groningen
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Hay Fever, Asthma
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
The clinical trial aimes to evaluate multiple large language models in respiratory disease consultations by comparing their performance to that of human doctors across three major medical consultation scenarios.
- Conditions
- Hay Fever, Asthma, Acute Upper Respiratory Infection, Pulmonary Embolism
- Trial name
- EPLLMMRDC (NCT06457269)
- Testing
- Diagnosis by three human doctors, Diagnosis by ChatGPT-3.5 (with search capabilities), Diagnosis by ChatGPT-3.5 (without search capabilities)
- Where
- China
- Volunteers
- 703 people
- Sponsor
- North Sichuan Medical College
Brain Tumor, Vascular Lesion
Factor XIII and Pulmonary Embolism in Neurosurgical Patients
Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy.
- Conditions
- Brain Tumor, Vascular Lesion, Factor XIII Deficiency, Pulmonary Embolism
- Trial name
- NCT01106937
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Thromboembolism, Acute Lymphoblastic Leukemia
Thromboembolic Complications Related to Asparaginase in Children With Acute Lymphoblastic Leukemia (ALL) Treated According to NOPHO ALL 2008
The study will examine the prevalence of venous thromboembolism in children with acute lymphoblastic leukaemia treated in accordance with NOPHO ALL-2008.
- Trial name
- NCT00982514
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Localized Resectable Adult Primary Liver Cancer, Stage III Childhood Liver Cancer
Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer
RATIONALE: Drugs used in chemotherapy, such as fluorouracil and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00238160
- Testing
- cisplatin, fluorouracil, adjuvant therapy
- Where
- 4 sites in Japan
- Sponsor
- Kyoto University
Carcinoma, Hepatocellular
Study of Folfox4 Chemotherapy Regimen to Prevent Early Postoperative Recurrence for HCC-PVTT Patients
This study is to investigate the efficacy and safety of Folfox4 chemotherapy regimen to prevent early recurrence for hepatocellular carcinoma patients with portal vein tumor thrombus following curative resection
- Trial name
- NCT02813096
- Testing
- folfox4 chemotherapy regimen
- Volunteers
- 500 people
- Sponsor
- Guangxi Medical University
Nephroblastoma With Vena Cava Thrombosis
Vascular Thrombus Involvement in Nephroblastoma
Nephroblastoma (Wilms tumor) is the most common kidney tumor in children. It is a malignant embryonic tumor with a good prognosis with more than 85% long-term survival with appropriate chemotherapy, surgery (which most often…
- Trial name
- VIN (NCT05195411)
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer, Venous Thromboembolism
Prophylaxis of Venous Thrombo-Embolism in Cancer Patients Under Palliative Care
To determine the efficacy and to measure the complications of prophylactic anticoagulation using low-molecular weight heparin in adult cancer patients under palliative care
- Trial name
- NCT00303407
- Testing
- nadroparin
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Venous Thromboembolism (VTE)
Study to Gather Information How Often Venous Thromboembolism Occurs in Prostate Cancer Patients in Sweden and How This Condition is Treated With Blood Thinners
Patients with cancer are at a significantly increased risk of experiencing a venous thromboembolism (VTE). VTE is defined by a blood clot in the leg or lower extremity (deep vein thrombosis) or a blood clot in the lung (pulmonary…
- Trial name
- PRACTISE (NCT03965741)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Apixaban(Eliquis), Pradaxa (Dabigatran etexilate)
- Where
- Sweden
- Volunteers
- 97,765 people
- Sponsor
- Bayer
Thromboembolism
Warfarin in Preventing Blood Clots in Cancer Patients With Central Venous Catheters
RATIONALE: Warfarin may be effective in preventing the formation of blood clots in patients with central venous catheters. PURPOSE: Randomized clinical trial to study the effectiveness of warfarin in preventing blood clots in…
- Trial name
- NCT00024297
- Testing
- warfarin
- Where
- 38 sites in United Kingdom
- Sponsor
- Cancer Research Campaign Clinical Trials Centre
Lymphoma, Acute Lymphoblastic Leukemia
A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
The purpose of this study is to compare the effect of a blood thinning drug called Apixaban versus no administration of a blood thinning drug, in preventing blood clots in children with leukemia or lymphoma.
- Trial name
- NCT02369653
- Testing
- Apixaban, No systemic anticoagulant prophylaxis
- Where
- 96 sites in United States, Australia and 10 more
- Volunteers
- 512 people
- Sponsor
- Bristol-Myers Squibb
Venous Thromboembolism
Fragmin for the Treatment of Acute VTE in Pediatric Cancer Patients
Three month treatment of acute VTE with Fragmin in pediatric cancer patients
- Trial name
- NCT00952380
- Testing
- dalteparin
- Where
- 26 sites in United States, Norway and 3 more
- Volunteers
- 38 people
- Sponsor
- Pfizer
Multiple Myeloma, Venous Thromboembolism
Thrombosis in Patients With Multiple Myeloma in an University Medical Center
Main research question: What is the present venous thrombosis incidence and what are the current practices of prescribing thromboprophylaxis in patients with multiple myeloma (MM)? Design: The present study is a retrospective…
- Conditions
- Multiple Myeloma, Venous Thromboembolism, Arterial Thromboembolism
- Trial name
- THRIMM (NCT05541978)
- Testing
- Multiple myeloma
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Catalina Codreanu
Healthy Blood Donors, Moli-sani Subjects
Hypercoagulation Screening in Cancer
There is a complex, mutual relationship between cancer and thrombosis. Indeed, the tumor has the capacity to activate the hemostatic system and this leads to an increased thrombotic risk in cancer patients.
- Conditions
- Healthy Blood Donors, Moli-sani Subjects, Cancer Patients
- Trial name
- HYPERCAN (NCT02622815)
- Where
- 8 sites in Italy
- Volunteers
- 16,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII