Clinical trials: Type I Diabetes
Type 1 Diabetes Mellitus
Pilot Study: Intensive Education in a Residential Camp Setting for Families of Young Children With Type 1 Diabetes
18 preschool aged children and their families will attend structured, multidisciplinary, family-centered intensive education sessions over a 3-day weekend in a residential camp setting to address the unique challenges of managing…
- Trial name
- TotCamp (NCT02432586)
- Testing
- Intensive Education
- Volunteers
- 18 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus, Type 1
Sleep Quality Among Children And Adolescents With Type 1 Diabetes Mellitus
Sleep is an important health behavior for children and adolescents due to the impact it has on both mental and physical development.
- Trial name
- NCT05686655
- Testing
- questionnaire about sleep quality in diabetic children
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Type 1 Diabetes Mellitus, Adolescents
Could the Advanced Hybrid Closed-Loop System Algorithm Provide Postprandial Normoglycemia After a High-Fat, High-Protein Meal
AHCL Systems Could Cover Postprandial Glycemic Response After High Fat and High Protein Meals
- Trial name
- AHCLS T1D nutr (NCT06848933)
- Testing
- Test meal, Each participant will consume the test meal when on Medtronic Minimed 780G and will consume test meal on Medtronic Minimed 780G on manual mode, Advanced hybrid closed loop system mode
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Coping Behavior, Emotional Distress
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
The Creative Arts Diabetes Initiative will offer facilitated art therapy with a group/peer-support environment to two groups of youth/young adults, one with type 1 diabetes, and one with type 2 diabetes.
- Conditions
- Coping Behavior, Emotional Distress, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- CADI (NCT02790892)
- Testing
- Art therapy - pre and post test measures
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Pharmacokinetic Properties of FIAsp in Children, Adolescents and Adults With Type 1 Diabetes
This trial is conducted in Europe. The aim of the trial is to investigate the pharmacokinetic (the exposure of the trial drug in the body) properties of FIAsp (faster-acting insulin aspart) in children, adolescents and adults…
- Trial name
- NCT02035371
- Testing
- Faster-acting insulin aspart, insulin aspart
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Family Routines Enhancing Adolescent Diabetes by Optimizing Management
A three month randomized study to examine the potential benefits of sleep extension in tandem with clinical trial on diabetes management in youth with type 1 diabetes.
- Trial name
- FREADOM (NCT02974309)
- Testing
- Sleep Extension, Routine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Arizona
Type 1 Diabetes Mellitus, Hypoglycemia
Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes
The purpose of this study is to determine the most effective treatment option for managing naturally occurring hypoglycemia in children with type 1 diabetes. Hypotheses: 1.
- Trial name
- NCT00706693
- Testing
- Ingestion of BD glucose tablets (TM), Ingestion of Skittles (TM), Ingestion of Fruit to Go (TM)
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Calgary
Type 1 Diabetes Mellitus
B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- NCT01049633
- Testing
- Allogeneic Pancreatic Islet Cells, Sirolimus, Basiliximab
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetes Mellitus, Type 1, Hyperglycemia, Postprandial
Effect of Protein Intake on Post Prandial Hyperglycemia in Children and Adolescents With Type1 Diabetes Mellitus
In type 1 Diabetes Mellitus, patients receive insulin doses if they consume specific amounts of carbohydrates. Currently, insulin is not being administered for consumption of protein although studies in adults show that consuming…
- Trial name
- NCT04655131
- Testing
- Whey protein isolate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetes Mellitus, Type 1
Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes
The primary objective of the study is: To compare the effect of ATG treatment together with intensified insulin therapy (Group 1) on fasting and glucagon-stimulated C-peptide production with that of intensified insulin therapy…
- Trial name
- NCT00190502
- Testing
- Polyclonal anti-T-cell antibodies
- Where
- Czechia
- Volunteers
- 28 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Type 1 Diabetes Mellitus
Omnipod Horizon™ Automated Glucose Control System Preschool Cohort
Subjects will undergo a 14-day outpatient, standard therapy phase during which sensor and insulin data will be collected. This will be followed by a 94-day (13-week) hybrid closed-loop phase conducted in an outpatient setting…
- Trial name
- NCT04476472
- Testing
- Omnipod Horizon™ Automated Glucose Control System
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- Insulet Corporation
Type 1 Diabetes Mellitus
Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes
Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verapamil is an L-type calcium channel blocker that has been used for decades to treat hypertension and…
- Trial name
- NCT07804849
- Testing
- Verapamil oral
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Type 1 Diabetes
Diabetes Transition Coordinator Study
The goal of this interventional study is to assess the effects and evaluate the implementation of a pediatric to adult care transition intervention in youth with T1D on clinical, patient-reported, and implementation outcomes…
- Trial name
- NCT06300047
- Testing
- Non-Medical Transition Coordinator
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 1
Evaluation of Novel Trend Arrow Adjustment Tool for Diabetes Patients Using Continuous Glucose Monitoring to Guide Insulin Bolus Adjustment (TAAT Study)
Continuous glucose monitoring (CGM) provides up to 288 blood glucose levels per day, updated every 5 minutes and displayed in real-time on the insulin pump, which can be used to enhance delivery of insulin through pump therapy.
- Trial name
- TAAT (NCT02064647)
- Testing
- Trend Arrow Adjustment Tool, 10/20% bolus adjustment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Diabetes Mellitus, Type 1, Self-Management
Promoting Self-management Behaviors in Adolescents With Type 1 Diabetes, Using Digital Storytelling
The aim of this study was to evaluate the effects of digital storytelling on the Self-Management behavior of adolescents with type 1 diabetes (TID).
- Trial name
- NCT04608058
- Testing
- Digital storytelling training, Routine training
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Nahid Zarifsanaiey
Diabetes Mellitus, Type 1
Omega-3 Fatty Acids Supplementation Improves Early-stage Diabetic Nephropathy and Subclinical Atherosclerosis in Pediatric Patients With Type 1 Diabetes
The investigators conducted this randomized-controlled trial to assess the effect of oral omega-3 supplementation on glycemic control, lipid profile, albuminuria level, kidney injury molecule-1 (KIM-1) and carotid intima media…
- Trial name
- NCT05980026
- Testing
- oral omega-3 fatty acids supplementation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Type 1 Diabetes Mellitus
Basic Hematological Parameters and Coagulation Profile in Type 1 Diabetic Children
Diabetes mellitus is a group of chronic metabolic diseases characterized by hyperglycemia .Type 1 diabetes is a heterogeneous disease related to the destruction of pancreatic beta cells and is a result of absolute lack of insulin…
- Trial name
- NCT06897904
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes Mellitus
Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus
This is a multicenter, randomized, partial-blinded, five-arm, placebo-controlled study of human plasma-derived alpha1-proteinase inhibitor (alpha1-PI) in children (ages 6-11 years old) and teens/adults (ages 12-35 years old) with…
- Trial name
- NCT02093221
- Testing
- 180 mg/kg Alpha1-PI, 90 mg/kg Alpha1-PI
- Where
- 36 sites in United States
- Volunteers
- 76 people
- Sponsor
- Grifols Therapeutics LLC
Type 1 Diabetes, HbA1c
Steno Diabetes Dialogue Cards Teaching on Group Education on Blood Sugar Control in Adolescents With Type 1 Diabetes
The Type 1 diabetes is the autoimmunity system produces the antibody which starts to attack the B lymphocytes while the autoimmunity is also been attacked.
- Conditions
- Type 1 Diabetes, HbA1c, Self-management
- Trial name
- NCT05394532
- Testing
- Education
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Type 1
Effects of Structured Group Education on Quality of Life and Glycemic Control in Type 1 Diabetes
Patients with type 1 diabetes aged 15-65 years without major complications will be randomized either to usual care or to a structured group education program, with 6 four-hour weekly interactive sessions devoted to diabetes…
- Trial name
- NCT02443532
- Testing
- Structured group education, Individual education
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
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