Clinical trials: Type Two Diabetes Mellitus
Insulin-Dependent Diabetes Mellitus 1
Comparison of Two Different Insulin Dose Calculation Algorithms in Type 1 Diabetes
The aim of this study is to compare the impact of carbohydrate counting (CC) method which is standard insulin dose calculation algorithm and food insulin index (FII) method which is a new algorithm on postprandial glucose…
- Trial name
- NCT04131049
- Testing
- High GI calculated by CC (CHGI), Low GI calculated by CC (CLGI), High GI calculated by FII (FHGI)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- TC Erciyes University
Type 1 Diabetes
Transition of Adolescents and Young Adults With Diabetes From Pediatric to Adult Care
The purpose of the study is to compare two interventions for preparing diabetic teens and young adults for transition from pediatric to adult diabetes care.
- Trial name
- NCT01109797
- Testing
- Transition Social Behavioral Intervention, Diabetes Transition Clinic
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Kansas
Closed Loop, Diabetes Mellitus, Type 1
Diabeloop for Kids
An open-label, three-center, randomized, two-session, 4 days inpatient and 6-week follow-up home study phase, crossover study comparing Diabeloop closed-loop (CL) system and sensor-augmented pump (SAP) therapy.
- Conditions
- Closed Loop, Diabetes Mellitus, Type 1, Young Children (6 to 12 Years Old )
- Trial name
- DBL4K (NCT03671915)
- Testing
- Continuous Glucose Monitoring, External Insulin Pump, Diabeloop Software (Model predictive control)
- Where
- 3 sites in Belgium, France
- Volunteers
- 21 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Type 1 Diabetes, Hypoglycemia
Concordance of Hypoglycemia Measurement With Simultaneous Use of Two Devices for Continuous Glucose Measurement.
The aim of this study is to compare two frequently used sensors for continuous glucose monitoring (CGM); Freestyle Libre and Dexcom G 7.
- Trial name
- NCT06246578
- Testing
- Continuos glucose monitoring and blood glucose measurement
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Central Jutland Regional Hospital
Type2 Diabetes Mellitus
Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D)
The ultimate goal of this field trial is to systematically evaluate a novel care coordination tool for children with Type 2 Diabetes (T2D) in an office setting at Emory/Childrens Healthcare of Atlanta.
- Trial name
- GTG (NCT03926598)
- Testing
- Patient and/or Family Member Intervention, Certified Diabetes Educator Intervention, Physician Intervention
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Type 2 Diabetes
Implementation of Team Clinic for Type 2 Diabetes (TCT2)
The goal of this clinical trial is to learn if shared medical appointment is an acceptable way to deliver care to youth with type 2 diabetes.
- Trial name
- NCT06923046
- Testing
- Standard of Care, Shared Medical Appointments
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Children's Hospital Los Angeles
Diabetes Mellitus, Type 2
Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus Treated With Metformin
This is a multicenter, randomized, blinded, placebo-controlled study to assess the effects on glucose control of AC2993 as compared to placebo in patients with type 2 diabetes.
- Trial name
- NCT00039013
- Testing
- AC2993
- Where
- 129 sites in United States
- Volunteers
- 336 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2
A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin
This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes.
- Trial name
- ONWARDS 2 (NCT04770532)
- Testing
- Insulin degludec, Insulin Icodec
- Where
- 88 sites in United States, Bulgaria and 7 more
- Volunteers
- 526 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
Extension Study for 2993-112
This multicenter, open-label extension study of Protocol 2993-112 is designed to assess long-term glucose control as measured by HbA1c (glycosylated hemoglobin) and to evaluate long-term safety and tolerability in subjects…
- Trial name
- NCT01789957
- Testing
- AC2993
- Where
- 226 sites in United States, Canada
- Volunteers
- 225 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
Simplified Meal Approach Using Hybrid Closed-loop Insulin Delivery in Youth and Young Adults With Type 1 Diabetes
The purpose of the study is to examine whether a simplified meal approach (as compared to exact carbohydrate counting) can alleviate the need of carbohydrate counting without worsening postprandial control in youth and young…
- Trial name
- SMASH (NCT05481034)
- Testing
- SMA bolus option, Exactly estimated carbohydrate content bolus option
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- Lia Bally
Diabetes Mellitus
Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents
The purpose of the study is to compare the effect in blood sugar control between Lantus and twice daily intermediate acting insulins (NPH or Lente) when used as the basal insulin in a multiple daily injection setting with fast…
- Trial name
- NCT00046501
- Testing
- Lantus (insulin glargine [rDNA origin] injection), Humulin N, Humulin L
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Sanofi