Clinical trials: Ulcer, Leg
Wounds, Pressure Ulcer
Kerecis Real-World Fish Skin Graft Registry
Multi-center, observational (i.e., non-interventional), open-label, real-world Registry on the Use of Kerecis Devices
- Conditions
- Wounds, Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
- Trial name
- ISACOD (NCT06384183)
- Testing
- Kerecis Fish Skin Graft
- Where
- 6 sites in United States
- Volunteers
- 600 people
- Sponsor
- Kerecis Ltd.
Diabetic Foot Ulcer
The Effect of Breathing Exercise and Pressurized Cold Application on Pain and Anxiety During Sharp Debridement
In our planned study, it is envisaged that patients who receive breathing exercises and pressurized cold application will experience a decrease in the level of pain they feel during the debridement process, a decrease in their…
- Trial name
- NCT06886633
- Testing
- Breathing exercise, Experimental: Pressurized Cold Application Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Harran University
Diabetic Foot, Amputation
Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
This study explored the pattern and type of amputations performed on patients with diabetic foot who were admitted to our institution, as well as the 7-year mortality rate of patients with diabetic foot at the same institution.
- Trial name
- NCT05123157
- Testing
- NO intervention
- Where
- Saudi Arabia
- Volunteers
- 358 people
- Sponsor
- King Abdulaziz University
Sickle Cell Disease, Leg Ulcers
Resolution of Sickle Cell Leg Ulcers With Voxelotor
This study is a Phase 3, multicenter, randomized, placebo-controlled study to evaluate the efficacy of voxelotor and standard of care for the treatment of leg ulcers in participants with sickle cell disease.
- Trial name
- RESOLVE (NCT05561140)
- Testing
- Voxelotor Oral Tablet
- Where
- 23 sites in Brazil, Kenya and 1 more
- Volunteers
- 88 people
- Sponsor
- Pfizer
Diabetes Mellitus, Foot Ulcers
Ulcer Monitoring in Diabetes Mellitus
Telemedicine technology enables a direct and online text- and image communication in the treatment system from patient to the ulcer specialist.
- Trial name
- Telesaar (NCT01608425)
- Testing
- telemedicine consultations
- Where
- 6 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Johnny Froekjaer
Venous Ulcer
Axial Ablation Versus Terminal Interruption of the Reflux Source
This randomised trial aims to compare the effect on ulcer healing of different means of managing venous reflux in the lower limb.
- Trial name
- AAVTIRS (NCT04484168)
- Testing
- Terminal Interruption of the Reflux Source, Axial Ablation
- Where
- Ireland
- Volunteers
- 308 people
- Sponsor
- University College Hospital Galway
Flat Foot, Pressure Ulcer
Polyurethane Foam on the Heel for Prevention in Children
The post-operative treatment of pediatric patients operated for the correction of flat foot, sees today the use of preformed leg-foot splint (Walker) as an alternative to the application of plaster casts.
- Trial name
- SCHIUMABIMB (NCT03039179)
- Testing
- polyurethane foam dress
- Volunteers
- 80 people
- Sponsor
- Istituto Ortopedico Rizzoli
Venous Leg Ulcer
Trial of Compassionate Use of hp802-247 to Treat Venous Leg Ulcers in Subjects Who Have Failed Multiple Other Healing Technologies
Compound HP802-247 comprises two topical sprays, administered sequentially right after another; these deliver a suspension of fibroblasts and keratinocytes to the wound surface.
- Trial name
- NCT01320605
- Testing
- Weekly wound spray with components 1 and 2 of the compound HP802-247
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Atlantic Health System
Venous Leg Ulcer
Efficacy and Safety of URGOBD001 Compression System
Evaluation of the efficacy (wound epithelialization and time to closure) and safety (emergence and nature of adverse event) of the new URGO BD001 compression system versus a reference compression in the local treatment of venous…
- Trial name
- FUTURE (NCT05158764)
- Testing
- Venous compression system of the lower limbs stage C6 / C6r of the CEAP classification
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Laboratoires URGO
Primary Health Care, Diabetes
Improvement of Diabetic Foot Care in Salamanca Through the Implementation of Standardized Protocols.
Introduction: Diabetic foot (DF) is among the most prevalent complications affecting individuals with diabetes. In Salamanca, 25,631 individuals are enrolled in the Diabetes Care Service, with only 3.06% undergoing a foot…
- Conditions
- Primary Health Care, Diabetes, Diabetic Foot
- Trial name
- NCT06250049
- Testing
- Diabetic foot care protocol, Group education sessions for patients and/or caregivers
- Where
- Spain
- Volunteers
- 25,631 people, healthy volunteers welcome
- Sponsor
- Sanidad de Castilla y León
Platelet-Derived Growth Factor, Diabetic Foot
Evaluation of the Safety Follow-up of Becaplermin or Placebo Gel Following Treatment of Chronic, Full Thickness Diabetic Ulcers
The purpose of this study is to retrospectively evaluate the safety of sterile becaplermin gel compared with sterile placebo gel treatment 12 months or more after the last dose was administered in 1 of 2 double-blind trials…
- Conditions
- Platelet-Derived Growth Factor, Diabetic Foot, Neoplasms
- Trial name
- NCT00740922
- Volunteers
- 563 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Skin Ulcers, Sickle Cell Anemia
Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers
OBJECTIVES: I. Compare the efficacy of local care alone vs local care plus arginine butyrate in terms of healing rate in patients with refractory sickle cell ulcers. II.
- Trial name
- NCT00004412
- Testing
- Arginine Butyrate, Standard local care dressing
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Susan P. Perrine
Diabetic Foot
Bacteriological Study of Diabetic Foot and Antibiotic Sensitivity Pattern in Eastern India
The pattern of organism causing diabetic foot infection are presumed to vary from location to location depending on the antibiotic prescription practice, geographical locations, environmental variations and therapeutic…
- Trial name
- NCT01351701
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Sun Valley Hospital, Guwahati
Diabetic Foot Ulcer
Evaluating Plantar Foot Pressure in a Novel Diabetic Offloading Device
The impacts from diabetes are both patient related and healthcare based. Offloading is recognised as the priority treatment for healing neuropathic and neuro-ischaemic plantar foot ulcers.
- Trial name
- NCT04336176
- Testing
- PulseFlow DF boot, Usual standard of care
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Leeds
Diabetic Foot
Cost-effectiveness Evaluation of Two 10% Urea Creams in Patients With Diabetic Foot Syndrome
Randomised, double-blind, cost-effectiveness clinical trial of two 10% urea creams purchased in pharmacies and supermarkets in patients with diabetic foot syndrome.
- Trial name
- NCT05588258
- Testing
- Participants were given the 10% urea cream purchased in pharmacy or supermarket as appropriate after randomisation and their foot skin quality was assessed by validated questionnaire.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Diabetic Foot Ulcer
Orthotic Treatment of Diabetic Foot Ulcers
The United States Department of Veterans Affairs spends an estimated $1.5 billion a year on healthcare for patients with diabetes. The prevalence and complications of diabetes increase with age.
- Trial name
- NCT05094037
- Testing
- Removable cam walker boot, Counseling
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Charcot Joint, Diabetic Foot
Characterizing and Diagnosis's of the Charcot Foot (Charcot Osteoarthropathy) in Diabetic Patients
The condition Charcot foot has been known in more than 130 years, and yet there still remains a large effort to find the cause, diagnostic and medical treatment of the condition.
- Trial name
- NCT00157222
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Diabetic Foot Ulcer, Diabetes Complications
Characteristics of Diabetic Foot Ulcer Patients
This study examines the demographic, clinical, and laboratory characteristics of patients with diabetic foot ulcers admitted to 5 Azar Hospital, Gorgan, in 2024.
- Trial name
- NCT07188337
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Golestan University of Medical sciences