Clinical trials: Ulcer, Leg
Leg Ulcer, Compression; Vein
Haemodynamics Variations of Transcutaneous Oxygen in Patient With Areterio-venous Leg Ulcers Under Venous Compression
Arterio-venous leg ulcers are real problems when it comes to public health because it has a major cost and leads to social and professional handicap.
- Trial name
- NCT03725111
- Testing
- venous compression
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Caen
Lower Limb Ulcers
A Comparison of Automatic ABPI vs Manual ABPI Device Scores
The aim of the study is to compare the Ankle Brachial Pressure Index (ABPI) scores of two devices. The two devices that will be compared are the MESI MD ABPI automatic device and the Huntleigh Dopplex manual device.
- Trial name
- NCT06557538
- Testing
- Automatic Ankle Brachial Pressure Index device assessment, Manual Ankle Brachial Pressure Index assessment
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- University of Southampton
Venous Leg Ulcer
Cyanoacrylate Closure for Treatment of Venous Leg Ulcers
Venous leg ulcers (VLUs) are a common wound with significant morbidity and cost, and suboptimal therapeutic options. VLUs result from chronic venous insufficiency, including venous reflux and post-thrombotic syndrome.
- Trial name
- NCT04011371
- Testing
- Cyanoacrylate closure
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Amputations, Diabetes
Clinical Trial of Footwear in Patients With Diabetes
A Seattle VA study indicated lower extremity ulcers preceded 84% of diabetic amputations. Nearly half of the events that ban the causal chain leading to ulcers and amputation were initiated by ill-fitting footwear.
- Conditions
- Amputations, Diabetes, Lower Extremity Ulcers
- Trial name
- NCT00032864
- Sponsor
- US Department of Veterans Affairs
Chronic Foot Ulcers
DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes
A randomized versus placebo trial designed to evaluate the clinical and humoral effects of 4 months of vildagliptin on healing of chronic ulcers in type 2 diabetes.
- Trial name
- NCT01472432
- Testing
- vildagliptin
- Where
- Italy
- Volunteers
- 106 people
- Sponsor
- University of Campania Luigi Vanvitelli
Diabetic Foot Ulcer
The Feasibility of a Facebook Group-based Program for Foot Self-management Support of Adults With Diabetes in Canada
The primary objective of this study is to examine the feasibility of a Facebook group-based program to support adults with diabetes in their foot self-care and prevention of foot ulcers. The sub-objectives are: 1.
- Trial name
- NCT04395521
- Testing
- Diabetic foot self-management support
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Helen Obilor
Diabetes Mellitus, Diabetic Foot
Educational Interventions on Diabetic Foot Care
Diabetes mellitus currently affects 463 million people worldwide. One of the most serious complications of diabetes is the diabetic foot.
- Trial name
- NCT04811989
- Testing
- Instructive video on diabetic foot care, Informative leaflet with real-time guided reading, Informative leaflet to read at home
- Where
- 2 sites in Portugal
- Volunteers
- 71 people
- Sponsor
- University of Minho
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01154374
- Testing
- MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Skingenix, Inc.
Diabetic Foot Ulcers
Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers
A Multicenter, Prospective, Randomized Controlled Comparative Parallel Study To determine the safety and effectiveness of EpiCord as compared to standard of care (SOC) therapy for the treatment of chronic, non-healing diabetic…
- Trial name
- NCT02844660
- Testing
- EpiCord, Standard of Care
- Where
- 13 sites in United States
- Volunteers
- 130 people
- Sponsor
- MiMedx Group, Inc.
Venous Leg Ulcer (VLU), Compression Bandages
A Randomized Non-Inferiority Study of Mepi™ Press 2 vs UrgoK2® for Compression Therapy in Venous Leg Ulcers
Venous leg ulcers (VLUs) account for approximately 70% of all lower limb ulcers and affect an estimated 0.032% to 1% of the population in Western countries, corresponding to approximately 265,000 to 650,000 individuals in France.
- Trial name
- NCT07600489
- Testing
- Compression bandage system (Mepi™ Press 2), Compression bandage system (UrgoK2®), Wound Dressing Material
- Where
- 8 sites in France
- Volunteers
- 386 people
- Sponsor
- Molnlycke Health Care AB
Venous Leg Ulcer
Combined Electromagnetic Field and a Plantar Resistance Exercise With Venous Leg Ulcer
The purpose of this study will investigate the effects of combined electromagnetic field and a plantar resistance exercise therapy versus electromagnetic field on healing of venous leg ulcer .
- Trial name
- NCT05410613
- Testing
- electromagnetic field and a plantar resistance exercise, Pulsed electromagnetic field, usual care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mona Mohamed Taha
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Chronic Skin Ulcer, Diabetic Foot Ulcer
Comparison of Platelet-Rich Plasma Dressing Versus Normal Saline Dressing for Chronic Non-Healing Ulcers
This randomized controlled trial will compare platelet rich plasma dressing with normal saline dressing for the treatment of chronic non healing cutaneous ulcers, including diabetic foot ulcers, venous leg ulcers, pressure…
- Trial name
- NCT07420868
- Testing
- Platelet Rich Plasma Dressing, Normal Saline Dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Multan Medical And Dental College
Diabetic Foot Ulcer
Effect of Virtual Reality on Pain, Anxiety and Vital Signs During Diabetic Foot Care
This study aims to determine the effects of a virtual reality (VR) intervention on pain level, state anxiety, and vital signs during foot care in individuals with diabetic foot ulcers.
- Trial name
- NCT07586423
- Testing
- VR, Standard Diabetic Foot Care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Malatya Turgut Ozal University
Diabetes Mellitus
Assessing Diabetic Foot Ulcer Microcirculation With High-frequency Contrast Enhanced Ultrasound
The objective of this observational study is to investigate and validate the utility of high-frame-rate ultrasound imaging technology for dynamic observation of the blood perfusion process at the site of ulcer wounds in…
- Trial name
- NCT06309082
- Testing
- Amputation, Debridement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Ischemic Foot Ulcers
The Role of Percutaneous Angioplasty in Ischemic Leg Ulcer Healing
The aim of our study was to evaluate the technical and clinical effectiveness of PTA in the management of ischemic foot ulcers. All consecutive patients presenting with a foot ulcer at the outpatient Vascular surgery clinic of…
- Trial name
- NCT03057080
- Testing
- Percutaneous transluminal angioplasty (PTA)
- Volunteers
- 161 people
- Sponsor
- University of Crete
Diabetes Type I, Diabetes Type II
Feasibility Study of DermGEN for Diabetic Foot Ulcer Treatment
The purpose of this clinical trial is to perform a limited pilot study to determine the safety and feasibility of DermGEN in the treatment of non-healing diabetic foot ulcers (DFU). This will be a one-arm prospective study.
- Trial name
- NCT02184455
- Testing
- DermGEN
- Where
- 2 sites in Canada
- Volunteers
- 11 people
- Sponsor
- Dr. Paul F. Gratzer
Diabetic Foot, Pedal Ulcers
Randomized, Prospective Evaluation of the Toad Brace in Plantar Ulcer Off-loading and Healing
The TOAD Medical Corporation Brace is a novel device that completely off-loads the foot and has been shown to heal ulcers at a rapid rate in preliminary experience in patients with plantar ulcers.
- Trial name
- NCT02052817
- Testing
- Optimal Medical Therapy Debridement + Toad Brace, Optimal Medical Therapy - Debridement
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Toad Medical Corporation
Foot Ulcer, Diabetic
The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals With Diabetic Foot Ulcers
The rise in diabetes incidence has led to a corresponding increase in diabetes-related complications. Diabetic foot ulcers, a severe consequence of diabetes, have substantial impacts on patients, the social environment, overall…
- Trial name
- NCT06023810
- Testing
- Watson's human care theory-based motivational interviewing method
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Okan University
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