Clinical trials: Underage Drinking
Adolescent Alcohol Use
Hybrid Type 1 Trial of a Parent-Based Intervention Addressing Social Media and Adolescent Alcohol Use
The central goal of this application is to conduct a Hybrid Type 1 effectiveness-implementation randomized controlled trial to test the comparative effectiveness of an alcohol and social media parent-based intervention (PBI)…
- Trial name
- NCT07664644
- Testing
- Combined Alcohol and Social Media PBI and PFI, Alcohol and Social Media PBI, Power of Parents
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Use Disorder
Enhancing the Effects of Alcohol Treatment With Lamotrigine
This study will help determine the tolerability and efficacy of the mood-stabilizing anticonvulsant lamotrigine in youth with alcohol use disorder.
- Trial name
- NCT04770493
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brown University
Binge Drinking, Underage Drinking, Drinking and Driving, Alcohol-Related Harms
Evaluation of Global Smart Drinking Goals Initiative
This study will evaluate effects of a multi-component, population-level intervention on alcohol use and related harms in six intervention cities relative to six matched comparison cities.
- Trial name
- GSDG (NCT03262259)
- Testing
- GSDG multi-component intervention
- Where
- United States
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- HBSA
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Substance-Related Disorders, Underage Drinking
Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students
The current study aims to test the efficacy of a family communication-based, novel, adaptable, and resource-efficient substance misuse preventive intervention for parents/guardians of pre/early adolescents (grades 5-7).
- Conditions
- Substance-Related Disorders, Underage Drinking, Drug Use
- Trial name
- NCT03925220
- Testing
- The SUPPER Project, Improving nutrition and physical activity among youth
- Where
- United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Tufts University
Heavy Drinking, Driving Under the Influence
Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care
Our goal is to conduct a large multi-site randomized controlled trial (RCT) of a promising computer-facilitated Screening and clinician Brief Intervention (cSBI) system designed for delivery by pediatric primary care clinicians…
- Conditions
- Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
- Trial name
- ASPIRE (NCT04450966)
- Testing
- Computer-facilitated Screening and Brief Intervention
- Where
- 3 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Alcohol Use Disorder
N-Acetylcysteine for Adolescent Alcohol Use Disorder
This is a 8-week randomized, placebo-controlled trial testing the effects of N-acetylcysteine (NAC), on a platform of weekly evidence-based brief alcohol intervention for 120 adolescents with alcohol use disorder (AUD).
- Trial name
- NCT03707951
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Medical University of South Carolina
Alcohol Drinking
Businesses That Care - Zacatecas
The purpose of this study is to develop and implement a community-based prevention initiative to prevent youth alcohol use and abuse in Zacatecas, Mexico.
- Trial name
- NCT04166162
- Testing
- Brief Intervention Motivational Interviewing (BIMI) Intervention, Tomando Buenas Decisiones (TBD) Intervention, Social Development Strategy (SDS) Intervention
- Where
- Mexico
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- University of Miami
Alcohol Abuse, Risk Behavior
Computerized Screening and Brief Physician Advice to Reduce Teen Drinking
The goal of this project is to adapt a computerized Screening and Brief Advice (SBA) protocol that has demonstrated efficacy in reducing underage drinking among adolescent primary care patients and then to test it in a multi-site…
- Trial name
- NCT00849589
- Testing
- Computerized screening and brief physician advice, Computerized SBA with technological extenders
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Underage Drinking
Norms Re-education to Promote Engagement in Parent-based Interventions
A randomized controlled trial (RCT) will be conducted to evaluate both the short-term and long-term efficacy of innovative, incentive-free parent-based interventions (PBIs) designed to reduce underage drinking on college…
- Trial name
- NCT06871982
- Testing
- PNF+ PBI, SNMC+ PBI, PH+ PBI
- Where
- United States
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Dating Violence, Dating Abuse
A Brief Intervention
This randomized controlled trial (RCT) study is a small scale test of the feasibility and preliminary efficacy of a brief motivational interview-style intervention.
- Trial name
- NCT01632176
- Testing
- Brief, motivational interview and one booster session
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston University
Alcohol Misuse
Project U Connect - Optimizing Brief Alcohol Intervention for Underage Drinkers in the ER
The Emergency Department (ED) setting is a unique point of access for reaching underage drinkers (age 14-20). With the aid of computer technology, this study will screen underage drinkers in the ED and fully test promising…
- Trial name
- NCT01051141
- Testing
- Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
- Where
- United States
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alcohol Drinking, Control
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
- Trial name
- NCT03238300
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Underage Drinking
Facilitating Adolescent Self-Change for Alcohol Problems
This present multi-site investigation compares a voluntary brief intervention for adolescent alcohol problems to an educational comparison condition.
- Trial name
- NCT01690026
- Testing
- Motivation interviewing based brief intervention, Standard Intervention
- Where
- 3 sites in United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol Use, Adolescent
Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems
Intervention for mild severity alcohol use among U.S. teens is crucial, as alcohol is the most commonly used substance in this age group, yet few receive the necessary interventions.
- Conditions
- Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
- Trial name
- NCT06593652
- Testing
- Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
- Where
- United States
- Volunteers
- 615 people
- Sponsor
- Indiana University
Adolescent Alcohol Use
Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care
Alcohol use is prevalent in U.S. adolescents and contributes to adverse health outcomes in this population. Care for adolescent alcohol use is lacking in most pediatric primary care settings (PPC).
- Trial name
- PCORIMINDSET (NCT07059078)
- Testing
- Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training
- Where
- 13 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Johns Hopkins University
Underage Drinking, Driving Under the Influence
Project MADD - NIH Underage DUI and Ride
Project MADD was designed to attempt to curb the alarming trends related to drunk driving and to move the field forward by testing a brief parent-intervention's ability to change adolescents' drinking, impaired driving, and…
- Conditions
- Underage Drinking, Driving Under the Influence, Drinking, Teen
- Trial name
- NCT03506880
- Testing
- MADD Materials, Surgeon General Materials
- Where
- United States
- Volunteers
- 2,352 people, healthy volunteers welcome
- Sponsor
- Penn State University
Underage Drinking
Digitally Prompted Parenting: A Text Message Parent-Based Alcohol Intervention for Incoming College Students
This pilot randomized controlled trial (RCT) will evaluate both the feasibility and efficacy of Digitally Prompted Parenting (DPP), a text-message based parent intervention (tm-PBI) designed to prevent and reduce alcohol use…
- Trial name
- NCT06861660
- Testing
- Digitally Prompted Parenting, Active Control
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Alcohol Drinking
Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms
This study will help to determine whether the medication, topiramate, reduces alcohol use among adolescents with alcohol dependence.
- Trial name
- IMPACT (NCT01641445)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brown University
Substance Use
Primary Connections for Youth and Families
The goal of this clinical trial is to compare a standard adolescent-only approach to substance use screening, brief intervention, and referral to treatment to a in primary care settings.
- Trial name
- PCYF (NCT05964010)
- Testing
- Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI)
- Where
- United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University