Clinical trials: Upper Extremity Paralysis
Hemiplegic Cerebral Palsy
Virtual Reality With Mirror Therapy on Upper Limb Function
The goal of this clinical trial is to address the effect of (Virtual Reality) and (Mirror Therapy) together on upper limb function in hemiplegic Cerebral Palsy children , male or female ranged between 3 to 10 years of age .
- Trial name
- NCT06728475
- Testing
- virtual reality, mirror therapy, virtual reality with mirror therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Cerebral Palsy
Whole Body Vibration in Rehabilitation of Spastic Cerebral Palsy
Spasticity is one of the most common features in children with cerebral palsy (CP) and is evident in the majority of CP types such as hemiplegia, diplegia, quadriplegia, etc.
- Trial name
- WBV (NCT06077136)
- Testing
- whole body vibration, standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- University of Hail
Cerebral Palsy
The Effect of Sensory Integration Therapy on Upper Extremity Functions, Trunk Control and Balance in Children With Cerebral Palsy
In children with cerebral palsy, the interactions of the sensory systems, musculoskaletal system and central nervous system are damaged.
- Trial name
- NCT04802551
- Testing
- Sensory integration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Izmir Bakircay University
Unilateral Cerebral Palsy
HEMImprove 1.0 in Children and Adolescents With Unilateral Cerebral Palsy
This study aims to evaluate the effectiveness and usability of HEMImprove 1.0, a gamified mobile application designed to improve upper limb motor function in adolescents with unilateral cerebral palsy.
- Trial name
- HEMImprove-APP (NCT07041944)
- Testing
- HEMImprove APP, exercises to upper limb
- Volunteers
- 36 people
- Sponsor
- University of Castilla-La Mancha
Sports Physical Therapy
Effect of Plyometric Exercises on Upper Extremity Function in Children With Unilateral Cerebral Palsy
Plyometric training includes muscle contraction that moves rapidly from the eccentric to the concentric phase of movement while using proper biomechanics.
- Trial name
- NCT05313607
- Testing
- Designed physical therapy, Occupational therapy, Conventional Therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy
Constraint-Induced Movement Therapy and Action Observation Training in Children With Unilateral Cerebral Palsy
A randomized, controlled, and evaluator-blinded trail will be carried out comparing CIMT with or without AOT on sensorimotor outcome in children with unilateral CP aged 5 to 12 years.
- Trial name
- NCT03256357
- Testing
- Constraint-induced movement therapy, Action observation training
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- KU Leuven
Spastic Cerebral Palsy (sCP)
Rhythmic Stabilization Versus Ball Balancing
Spastic Cerebral Palsy (CP) is the leading cause of upper motor neuron syndrome (UMN) in children. The primary factors contributing to motor behavior disorders in these children are impairments in motor control and muscle…
- Trial name
- NCT06673849
- Testing
- Rhythmic Stabilization, Ball Balancing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Hemiplegia, Hemiplegic Cerebral Palsy
Actigraphs for Detection of Asymmetries
In hemiplegia quantitatively measurement of the asymmetry in the use of upper limbs could overcome the limitation of many outcome measures in which scores are dependent on the experience and training of the therapist.
- Trial name
- NCT03054441
- Testing
- Actigraph
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Spastic Hemiplegic Cerebral Palsy
The Effect of Mirror Therapy on Cerebral Re-organization, Functional Motor Skills, and Quality of Life in Hemiplegic Cerebral Palsy
The purpose of this study is to investigate brain reorganization, functional motor development, level of daily living activity and quality of life of upper extremity mirror therapy in children with spastic hemiplegic cerebral…
- Trial name
- NCT03612128
- Testing
- control group, intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Hacettepe University
Cerebral Palsy
Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Children With Cerebral Palsy
Cerebral Palsy (CP) is a major cause of impairments in child population. This disease justifies an intensive and prolonged multidisciplinary rehabilitation which can be optimised by robotics.
- Trial name
- NCT01700153
- Testing
- Robotic-assisted therapy, Classical therapy
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Spastic Hemiplegic Cerebral Palsy
Modified Constraint-Induced Movement Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is defined as a non-progressive lesion of the developing foetal or infant brain and causes variety of motor, sensory and cognitive impairments.
- Trial name
- NCT04064788
- Testing
- Consecutive Modified Constraint-Induced Movement Therapy, Traditional physiotherapy, Intermittent Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy (CP)
The Effects of Intensive Physiotherapy in Children With Spastic Cerebral Palsy
The aim of this study is to investigate the effects of a 2-week Neurodevelopmental Treatment (NDT)-based intensive physiotherapy program with active participation on postural control and selective motor control of the lower and…
- Trial name
- NCT07350096
- Testing
- Neurodevelopmental Therapy, Conventional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Cerebral Palsy
Evaluation the Feasibility and Effects of Kinect-based Computer Games as UE Training Tool in Cerebral Palsy Children
The purpose of this study is to design and evaluation the feasibility, effects of Kinect-based Computer Games as Upper Extremity Training Tool in Children with Cerebral Palsy.
- Trial name
- NCT02364245
- Testing
- Kinect, Traditional OT(30 Mins), Traditional OT(60 Mins)
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hereditary Spastic Paraplegia Type 50
Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.
Phase 3, open-label study to assess the efficacy and safety of a single lumbar intrathecal administration of MELPIDA in individuals with Hereditary Spastic Paraplegia Type 50 (SPG50).
- Trial name
- SPG50 (NCT06692712)
- Testing
- MELPIDA
- Where
- 2 sites in United States, Spain
- Volunteers
- 24 people
- Sponsor
- Elpida Therapeutics SPC
Cerebral Palsy
Efficacy of New Protocols in the Treatment of Upper Limb Dysfunctions in Patients With Cerebral Palsy
Cerebral palsy (CP) is the most common childhood motor disability. Weakness, spasticity, and loss of dexterity are the major problems in patients with CP.
- Trial name
- NCT02039284
- Testing
- SES, VCT, VRCIT
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chang Gung Memorial Hospital
Hemiplegia, Spastic
Motor Learning Approaches From Working on a Vertical Surface in Hemiplegic Children's Upper Limb Motor Skills
Working on a vertical surface is one of the best activities children can do to make themselves more successful in many areas as an infant which builds all those foundational skills required for the all-important task of…
- Trial name
- NCT05596513
- Testing
- motor learning and occupational therapy, Motor Learning Approaches From Working on a Vertical Surface
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Omnya Samy Abdallah Ghoneim
Cerebral Palsy
Effects of Hippotherapy on Functionality in Children With Cerebral Palsy
The purpose of this clinical review is to investigate the effect of hippotherapy in improving upper limb functionality in children with cerebral palsy. The main question it aims to answer is The questions are as follows: 1.
- Trial name
- NCT06550258
- Testing
- Equine-assisted therapy, Traditional Pediatric Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Cerebral Palsy, Diplegia
Effect of Upper Extremity Functional Skills on Quality of Life and Participation of the Children With Cerebral Palsy
Cerebral palsy (CP) is a movement and posture disorder accompanied by sensory, perception, cognition, communication and behavioral disorders that cause activity limitations by causing various non-progressive disorders of the…
- Conditions
- Cerebral Palsy, Diplegia, Upper Extremity Dysfunction, Quality of Life
- Trial name
- CP (NCT05194319)
- Testing
- All assessments of children (Demographic information, upper extremity skills, quality of life and participation levels)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanko University
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Hemiplegic Cerebral Palsy
Electromyography Biofeedback Training Versus Mirror Therapy on Muscle Activity, Range of Motion and Function of Upper Limb in Children With Hemiplegia
One of the main motor control issues in hemiplegic CP is spasticity, which affects the flexor muscles of the upper limb. This spasticity causes the limb to adopt a flexed posture, limiting the range of motion and contributing to…
- Trial name
- NCT07818616
- Testing
- Neurotrac Simplex electromyography biofeedback device, Mirror, a designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University