Clinical trials: Upper Extremity Paralysis
Cerebral Palsy
Comparative Effects of Myofascial Stretch and Contract-relax in Children With Spastic cp
Cerebral palsy (CP) is primarily a neuromotor disorder that affects the development of movement, muscle tone and posture.It is one of the three most common lifelong developmental disabilities, the other two being autism and…
- Trial name
- NCT06292507
- Testing
- MYOFASCIAL STRETCH, CONTRACT-RELAX TECHNIQUE
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Stroke Rehabilitation, Hemiplegia
The Effectiveness of Upper Extremity Isokinetic Strengthening in Post-stroke Hemiplegia
This randomised controlled study will investigate the effectiveness of isokinetic strengthening on the upper extremity functionality and strength in post-stroke hemiplegic patients.
- Trial name
- NCT03834311
- Testing
- isokinetic strengthening, exercise band strengthening
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Cukurova University
Spastic Cerebral Palsy (sCP)
Rhythmic Stabilization Versus Ball Balancing
Spastic Cerebral Palsy (CP) is the leading cause of upper motor neuron syndrome (UMN) in children. The primary factors contributing to motor behavior disorders in these children are impairments in motor control and muscle…
- Trial name
- NCT06673849
- Testing
- Rhythmic Stabilization, Ball Balancing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Stroke, Hemiplegia
Virtual Reality-Based Mirror Therapy and FES-Cycling in Stroke Rehabilitation
This randomized controlled, assessor-blinded study aimed to compare the effects of virtual reality-based mirror therapy (VRBMT) and functional electrical stimulation-assisted cycling (FES-cycling) when combined with conventional…
- Conditions
- Stroke, Hemiplegia, Upper Extremity Impairments
- Trial name
- NCT07666308
- Testing
- Conventional Rehabilitation, Virtual Reality-Based Mirror Therapy, Functional Electrical Stimulation-Assisted Cycling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Hemiplegic Cerebral Palsy
A Study on Safety of tDCS One-shot in UCP
The study aims to evaluate the safety and the feasibility of transcranial Direct Current Stimulation (tDCS) session in children and young adults with Unilateral Cerebral Palsy (UCP).
- Trial name
- NCT03137940
- Testing
- real tDCS
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- IRCCS Fondazione Stella Maris
Hemiplegia, Spasticity, Muscle
Investigation of the Effects of Upper Extremity Botulinum Toxin Application on Forearm Muscle Thickness and Motor Recovery in Patients With Hemiplegia
In this study, we aimed to examine the effects of the botulinum toxin (BoNT) application on muscle thickness and motor recovery in stroke patients.
- Trial name
- NCT07083752
- Testing
- Botulinum toxin application
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy, Stroke
Feasibility of the Portable YouGrabber System
The aim of the study is to determine the feasibility of the portable version of the YouGrabber® system in children with central motor disorders.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- YouGrabber (NCT02368223)
- Testing
- YouGrabber
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Children's Hospital, Zurich
Paralysis, Spinal Cord Injury
Restoring Arm and Hand Function With Non-invasive Spinal Stimulation
This study is to determine if non-invasive electrical stimulation of the spinal cord can help improve hand and arm function in people with paralysis who suffered a cervical spinal cord injury.
- Trial name
- NCT01906424
- Testing
- Transcutaneous Electrical Spinal Cord Stimulation
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- NeuroEnabling Technologies, Inc.
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Stroke, Hemiplegia
Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation
The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical stimulation (EES) of the spinal…
- Trial name
- Stroke-BSI (NCT07610850)
- Testing
- ARC-BSI Stroke system
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Tetraplegia, Plegia
Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity
The cervical spine is most commonly injured, accounting for 53.4% of spinal injuries. More than 40% of all spinal injuries occur at either C4, C5 or C6 levels leading to variable loss of function in the upper extremities.
- Conditions
- Tetraplegia, Plegia, Paresis, Cervical Spinal Cord Injury
- Trial name
- NCT01579604
- Testing
- Nerve reconstruction
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Cerebral Palsy (CP), Diplegic Cerebral Palsy
Effect of Intensive Segmental Trunk Training on Upper Extremity Function and Seated Postural Stability in Children With Spastic Diplegic Cerebral Palsy
The goal of this randomized controlled trial is to evaluate whether intensive segmental trunk training (ISTT) can improve upper extremity function and seated postural stability in children aged 4-12 years with spastic diplegic…
- Conditions
- Cerebral Palsy (CP), Diplegic Cerebral Palsy, Trunk Mobility, Upper Extremity Function
- Trial name
- NCT07692087
- Testing
- Intensive Segmental Trunk Training, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebral Palsy
Efficacy of New Protocols in the Treatment of Upper Limb Dysfunctions in Patients With Cerebral Palsy
Cerebral palsy (CP) is the most common childhood motor disability. Weakness, spasticity, and loss of dexterity are the major problems in patients with CP.
- Trial name
- NCT02039284
- Testing
- SES, VCT, VRCIT
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic
Functional Benefits of Multisite Surgery for the Upper Limb of Children With Cerebral Palsy
The aim of the study is to investigate the impact of individualized multisite neuro-orthopedic surgery of the upper limb in children with Cerebral Palsy on unilateral functional capacities and bimanual performance.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic, Infantile Hemiplegic Cerebral Palsy
- Trial name
- NCT04395729
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Upper Extremity Spasticity, Quadriplegic Cerebral Palsy
ICF-Based Evaluation of the Upper Extremity in Children With Quadriparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder characterized by abnormalities in muscle tone, movement, and motor skills resulting from permanent, non-progressive damage to the developing brain before, during, or after…
- Trial name
- NCT06585397
- Testing
- Grup 1
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Acıbadem Atunizade Hospital
Cerebral Palsy, Upper Extremity Dysfunction
The Effect of Upper Extremity Strengthening on Functionality, Muscle Strength and Trunk in Children With Cerebral Palsy
Cerebral Palsy (CP) is an activity limitation, movement and posture deficiencies in early stage of life. In 80% of these children, upper extremity (UE) dysfunctions are observed, which leads to loss of quality of life, resulting…
- Conditions
- Cerebral Palsy, Upper Extremity Dysfunction, Upper Extremity Functions, Muscle Strength
- Trial name
- NCT05115695
- Testing
- traditional physiotherapy approach, muscle strengthening exercise/Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Hereditary Spastic Paraplegia Type 50
Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.
Phase 3, open-label study to assess the efficacy and safety of a single lumbar intrathecal administration of MELPIDA in individuals with Hereditary Spastic Paraplegia Type 50 (SPG50).
- Trial name
- SPG50 (NCT06692712)
- Testing
- MELPIDA
- Where
- 2 sites in United States, Spain
- Volunteers
- 24 people
- Sponsor
- Elpida Therapeutics SPC
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Cerebral Palsy
Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy
The purpose of this study will employ clinical assessment tools to examine the effects of modified constraint-induced therapy (mCIT) on the more affected upper extremity of children with cerebral palsy.
- Trial name
- NCT01643239
- Testing
- Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm, Hospital-based mCIT, Hospital-based TR
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Sports Physical Therapy
Effect of Plyometric Exercises on Upper Extremity Function in Children With Unilateral Cerebral Palsy
Plyometric training includes muscle contraction that moves rapidly from the eccentric to the concentric phase of movement while using proper biomechanics.
- Trial name
- NCT05313607
- Testing
- Designed physical therapy, Occupational therapy, Conventional Therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University