Clinical trials: Urinary
Urinary Tract Infections
HD5 Levels in Catheter Versus Bag Urine Specimens in Young Children for the Diagnosis of UTI
Urinary tract infections (UTIs) are a common cause of bacteremia and serious bacterial infections in young children (2-24 months of age).
- Trial name
- NCT03163394
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Le Bonheur Children's Hospital
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug may kill more tumor cells.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00022633
- Testing
- gemcitabine hydrochloride, paclitaxel
- Where
- 92 sites in United States
- Volunteers
- 65 people
- Sponsor
- SWOG Cancer Research Network
Cancer, Bladder
Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer
Differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) is a cornerstone in the treatment plans.Therefore, this study will try to evaluate the sensitivity and reliability of…
- Trial name
- NCT05324033
- Testing
- multiparametric MRI on the bladder, diagnostic cystoscopy +/- TURBT
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Helwan University
Fever, Respiratory Tract Infections
A Retrospective, Blinded Validation of a Host-response Based Diagnostics
This is a retrospective, blinded, external validation study of a novel in-vitro diagnostic (IVD) assay that will include samples that were previously collected from febrile pediatric patients.
- Conditions
- Fever, Respiratory Tract Infections, Urinary Tract Infections, Gastroenteritis
- Trial name
- PATHFINDER (NCT01911143)
- Where
- 2 sites in Israel
- Volunteers
- 600 people
- Sponsor
- MeMed Diagnostics Ltd.
Recurrent Urinary Tract Infection
GAG Replacement vs URethral DIlAtatioN
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women.
- Trial name
- GUARDIAN (NCT03861260)
- Testing
- Rigid cystoscopy with urethral dilatation, Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
- Where
- United Kingdom
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Obstetric Fistula, Fistula
Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management
The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3)…
- Conditions
- Obstetric Fistula, Fistula, Fistula, Urinary, Fistula, Vaginal
- Trial name
- COPE (NCT05444504)
- Testing
- Cup, Cup+
- Where
- 3 sites in Ghana, Kenya
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Urinary Incontinence, Stress
Transvaginal Tape (TVT) Secur Versus TVT Randomised Controlled Trial (RCT)
This randomized multi-centre trial will recruit women with stress urinary incontinence who need surgical treatment for their condition.
- Trial name
- NCT00685217
- Testing
- TVT Secur (Gynecare), TVT (Gynecare)
- Where
- 4 sites in Canada
- Volunteers
- 74 people
- Sponsor
- University of Calgary
Sickle Cell Nephropathy
Clinical Utility of Urinary N-Acetyl-β-D-Glucosaminidase (NAG), Kidney Injury Molecule-1 (KIM-1), and Diffusion-Weighted Renal MRI for the Early Detection of Sickle Cell Nephropathy in Children
To evaluate the diagnostic performance of urinary N-acetyl-β-D-glucosaminidase (NAG) and kidney injury molecule-1 (KIM-1) Biomarkers for detection of early onset of Sickle Cell Nephropathy in children under HU therapy
- Trial name
- sickle nephro (NCT07785752)
- Testing
- Hydroxy Urea
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urinary Tract Infection (Diagnosis)
Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria
The aim of this study is to compare between effect of empirical antibiotic prophylaxis versus enhanced prophylactic measures on rate of urinary tract infection after Flexible ureteroscopy in Children.
- Trial name
- NCT07229755
- Testing
- Ceftriaxone (Rocephin®), Levofloxacin
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Diseases
Urinary Catheter Self-care Management
It is important for healthcare professionals to be sensitive to the needs of patients undergoing urinary catheterization. Patients and their relatives should be educated, guided and supported by nurses and other healthcare…
- Trial name
- NCT06179238
- Testing
- Education, without patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Overactive Bladder
Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic therapy.
- Trial name
- NCT00780832
- Testing
- Dietary Caffeine reduction, Anticholinergic medication
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- IWK Health Centre
Bladder and Bowel Dysfunction
Bladder and Bowel Dysfunction in Children
Background: Bladder and bowel dysfunction (BBD) is characterized by lower urinary tract symptoms accompanied by bowel complaints. BBD is a common condition in childhood.
- Trial name
- NCT05318365
- Testing
- Polyethylene Glycol 3350, Urotherapy
- Where
- 3 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Renal Insufficiency
Association Between COVID-19 and UTIs Caused by ESBL Organism in Infants
Urinary tract infections (UTIs) in infants and young children are one of the most common bacterial infections, usually febrile illness without source, frequently due to Enterobacteriaceae, mainly Escherichia coli.
- Trial name
- ABCUCEOI (NCT05630326)
- Testing
- comparing, prevalence, assessment, association
- Where
- Qatar
- Volunteers
- 5,600 people
- Sponsor
- Hamad Medical Corporation
Prostate Cancer
Primary Prostatic Lymphoma on a 66 Year-old Male in Mexico.
A 66-year-old male known case of diabetes and hypertension presented to the urology clinic with a 2-month history of lower urinary tract symptoms (LUTS), particularly poor flow, sense of incomplete bladder emptying, dysuria and…
- Trial name
- NCT07134504
- Where
- Mexico
- Volunteers
- 1 people
- Sponsor
- Instituto Mexicano del Seguro Social
Bladder Exstrophy
EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS
The purpose of this study is to evaluate the effectiveness and safety of a minimally invasive surgical procedure with ACT (Adjustable Continence Therapy) balloons implantation for the treatment of urinary incontinence in children…
- Trial name
- ACT (NCT04935918)
- Testing
- ACT
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Infantile Colic, Constipation - Functional
Bowel And Bladder Function in Infant Toilet Training
The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age.
- Conditions
- Infantile Colic, Constipation - Functional, Bladder Dysfunction, Toilet Training
- Trial name
- BABITT (NCT04082689)
- Testing
- Assisted Infant Toilet Training
- Where
- 6 sites in Sweden
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Urinary Bladder, Neurogenic, Urodynamics
Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing
The investigators have developed a novel pressure monitoring device that hooks to standard urinary catheters. The investigators will be testing how the pressure measurements recorded with this device compare to the gold standard…
- Trial name
- NCT03456089
- Testing
- Urodynamics Testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher Cooper
Urinary Tract Infections, UTI
Abdominal Ultrasonography in Urinary Tract Infection - When and Why?
Urinary tract infection (UTI) in a child may be the first symptom of congenital anomaly of the kidneys and the urinary tract (CAKUT). Thus, imaging diagnostics are warranted in children with first episode of UTI.
- Trial name
- NCT03270540
- Where
- Poland
- Volunteers
- 65 people
- Sponsor
- Medical University of Warsaw
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