Clinical trials: Urinary Lithiasis
Tamsulosin, Extracorporeal Shock Wave Lithotripsy
The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis
The aim of this study is to evaluate the clinical efficacy and safety of MET after ESWL in pediatric urolithiasis.
- Conditions
- Tamsulosin, Extracorporeal Shock Wave Lithotripsy, Stone, Kidney, Stone, Urinary
- Trial name
- NCT05759767
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Stone;Renal
Flexible Ureteroscopy Versus Mini-Percutaneous Nephrolithotomy for Treatment of Renal Stones
Management of nephrolithiasis is evolving rapidly, and various minimally-invasive urological procedures are currently available for treating patients with renal stones, including extracorporeal shockwave lithotripsy (ESWL)…
- Trial name
- NCT03932370
- Testing
- Flexible ureteroscopy, mini-Percutaneus nephrolithotomy
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urinary Calculi, Benign Prostatic Hyperplasia
Flexiva Pulse Registry
To obtain post-market safety and efficacy data for FlexivaTM Pulse High Power Single-Use Laser Fibers during lithotripsy and soft tissue procedure of holmium laser enucleation of the prostate (HoLEP).
- Trial name
- NCT05027971
- Testing
- Flexiva Pulse High Power Single-Use Laser Fibers
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Boston Scientific Corporation
Kidney Stone
Evaluation of Emergency Computed Tomography in Suspected Renal Colic. This is an Observational Retrospective Study Aimed to Evaluate Emergency Computed Tomography in Patients at the Emergency Department in Helsingborg, Sweden, With Suspected Acute Renal Colic.
The goal of this observational study is to learn more about diagnostics in patients with suspected acute renal colic at the emergency department.
- Trial name
- NCT06805149
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Region Skane
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pediatric Urinary Lithiasis
Stepwise Shock Wave Lithotripsy in Pediatric Urolithiasis
To evaluate and compare the results of conventional and stepwise shock wave lithotripsy treatment modalities in pediatric urinary lithiasis.
- Trial name
- NCT01807260
- Testing
- Shock wave lithotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- TC Erciyes University
Stone, Kidney
Clinical Efficacy of Mini-PCNLversus RIRS for the Management of Upper Urinary Tract Calculus (1-2.5 cm)
The goal of this [ type of study:]prospective randomized clinical trial. The main question is to compare the outcomes of mini-percutaneous nephrolithotomy (m-PCNL) and retrograde intrarenal surgery (RIRS) in treating upper…
- Trial name
- NCT06031103
- Testing
- mini-PCNL procedure, RIRS procedure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pediatric Bladder Stones, Bladder Calculi
Vacuum-Assisted Mini-Percutaneous Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones
This prospective randomized pilot study will compare vacuum-assisted mini-percutaneous cystolithotripsy with standard transurethral cystolithotripsy for the treatment of bladder stones in children.
- Conditions
- Pediatric Bladder Stones, Bladder Calculi, Pediatric Urolithiasis
- Trial name
- VAMPCL-Ped (NCT07614880)
- Testing
- Vacuum-Assisted Mini-Percutaneous Cystolithotripsy, Transurethral Cystolithotripsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
RENAL CALCULI
Safety and Efficacy of Herbmed Plus in Patients withRenal Calculi
More specifically, the present invention relates to a 'Herbal Preparation' that is useful for Treatment of Renal calculi Reduction in the stone size \& surface area The expulsion of stone Decreased need of…
- Trial name
- HerbmedPlus (NCT01355341)
- Testing
- HERBMED PLUS
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amai Charitable Trust
Nephrolithiasis
Is CYP24A1 Heterozygosity a Risk Factor for Nephrolithiasis?
Biallelic loss-of-function variants in CYP24A1 have been identified as a common genetic cause of autosomal recessive hypercalcemia (ARH, ORPHA 300547, 1 in 80,000 live births), characterized by low PTH (parathyroid hormone)…
- Trial name
- HETEROCYP (NCT07201701)
- Testing
- Supplementary blood samples for PBMC analysis at V2
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Urolithiasis
Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain
STUDY OBJECTIVE: This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of acute flank pain.
- Trial name
- NCT01318187
- Testing
- paracetamol, morphine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Pamukkale University
Pediatric Urolithiasis, Extracorporeal Shock Wave Lithotripsy
Optical Motion Capture-Assisted Ultrasound for Pediatric ESWL
The incidence of pediatric urinary system stones has shown an upward trend in recent years, and Extracorporeal Shock Wave Lithotripsy (ESWL) has become one of the most important minimally invasive treatments for pediatric upper…
- Conditions
- Pediatric Urolithiasis, Extracorporeal Shock Wave Lithotripsy, Optical Motion Capture, Ultrasound Localization
- Trial name
- NCT07299032
- Testing
- ESWL with Optical Motion Capture-Assisted Ultrasound Localization, ESWL with Conventional Ultrasound Localization
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Urinary (Renal or Ureteral) Stones
Comparison Between Two Shock Wave Regimens for Treating Urinary Stones
In order to check if a reduction in the frequency and total number of shocks delivered during extracorporeal shockwave lithotripsy (SWL) results in a great number of stone-free patients,the investigators compared two different…
- Trial name
- NCT01222325
- Testing
- extracorporeal shockwave lithotripsy (SWL)
- Where
- Brazil
- Volunteers
- 302 people
- Sponsor
- University of Sao Paulo General Hospital
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Hypercalciuria; Idiopathic, Nephrolithiasis
Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria
The investigator's objective is to compare and evaluate the impact of nutritional treatment vs. pharmacological treatment (hydrochlorothiazide) in bone mineral density in children with idiopathic hypercalciuria.
- Trial name
- HIC (NCT03951558)
- Testing
- Diet for calciuria prevention, Hydrochlorothiazide
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Kidney Stones, Percutaneous Nephrolithotomy
Paravertebral Versus Caudal Block in Pediatric PCNL
To compare the efficacy of Ultrasound guided thoracic paravertebral block versus ultrasound guided caudal epidural block in pediatric patients undergoing percutaneous nephrolithotomy
- Trial name
- NCT05012215
- Testing
- Paravertebral, Caudal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Cystinuria
Cystine Capacity Clinical Study (CysCap)
The purpose of this study is to determine whether urinary cystine capacity, an assay used to measure the amount of cystine in the urine, can be used to predict stone recurrence in patients with cystinuria.
- Trial name
- NCT02120105
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University