Clinical trials: Vaccination Pain
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Children's Distress During Flu Vaccination
Reducing Children's Distress Towards Flu Vaccinations
Millions of children in North America receive an annual flu vaccination, many of whom are at risk of experiencing severe distress. Children frequently use technologically advanced devices such as computers and cell phones.
- Trial name
- NCT01529021
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pain, Injection Site Reaction
Safety of Pediatric COVID-19 Vaccination
This is a prospective, observational study. During the study, children and adolescents (ages ≥ 5 to < 16) will be followed post administration of mRNA COVID-19 vaccines.
- Conditions
- Pain, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05157191
- Testing
- Observational
- Where
- 5 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Duke University
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Infant, Pain
Kangaroo Care Reduces Infant Pain Caused By Vaccination
The aim of this randomized controlled study determine the effect of KMC on pain in infants during vaccination.
- Conditions
- Infant, Pain, Kangaroo Mother Care, Nursing
- Trial name
- NCT04596137
- Testing
- İnfant pain management
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Pain
Effectiveness of Helfer Skin Tap Technique and ShotBlocker Technique
The purpose of this study is to examine the effectiveness of the Helfer Skin Tap Technique and the ShotBlocker Technique in reducing pain in babies receiving intramuscular vaccination.
- Trial name
- NCT06246266
- Testing
- Helfer Skin Tap Technique group, ShotBlocker Technique group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pain
Reduction of Pain in Childhood Vaccination in the Primary Care Nurse Vaccination Consultation
Non-randomized study with control group (CG) with the objective of analyzing the non-pharmacological analgesic efficacy of the "Painless Vaccine" protocol for the reduction of pain during vaccination in the population aged 2…
- Trial name
- NoVacPain (NCT06004258)
- Testing
- Painless Vaccination
- Where
- Spain
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen Macarena
Pain, Anxiety
Effects of Mother-Sung Lullabies on Infant Pain and Maternal Anxiety
Childhood pain can cause long-term and psychologically harmful effects. Music can reduce pain and anxiety. This study aimed to investigate the effects of the mother-sung lullaby during vaccine administration on vaccine-induced…
- Trial name
- NCT04692584
- Testing
- The Lullaby Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Pain
The Effect of ShotBlocker on Pain and Satisfaction During Measles-Rubella-Mumps Vaccination
Objective The aim of this study was to evaluate the effects of ShotBlocker administration during measles-mumps-rubella (MMR) vaccination on infants' pain level and mothers' satisfaction. Method.
- Trial name
- NCT06762938
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain, Fear
The Effect of the Helfer Skin Tap and Buzzy Application on Vaccination Pain, Fear and Crying Duration
To minimize the pain and discomfort during vaccination, one of three different methods will be used. One method involves using 'Buzzy,' a small, bee-shaped device that provides vibration and a cooling sensation; another involves…
- Conditions
- Pain, Fear, Crying
- Trial name
- NCT07749235
- Testing
- Bee Buzzy, Helfer Skin TAp
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ege University
Immunization
Prenatal Education About Infant Immunization Pain Management
There are numerous pain management strategies available for the management of infant immunization pain. The majority of infants, however do not benefit from these interventions, which causes them to suffer pain unnecessarily.
- Trial name
- NCT01707212
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Infants, Immunization
A Study of Two Injection Techniques to Reduce Pain in Infants Undergoing Immunization
Immunization injections are a significant source of pain for infants. Tactile stimulation (rubbing/applying pressure) may be an effective and feasible pain-relieving intervention - it is cost neutral, and has been shown to be…
- Conditions
- Healthy Infants, Immunization, Pain Management
- Trial name
- NCT01601197
- Testing
- Tactile stimulation
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Acute Pain
Improving Parental Soothing by Video
This study sets out to compare the effectiveness of a parent pain management coaching video that is 5-minutes in length. The investigators will be comparing an active-video to a placebo-video of equal length (and identical…
- Trial name
- NCT01826383
- Testing
- Active-Video
- Where
- 2 sites in Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- York University
Multisensory Stimulation
The Effect of Multisensory Stimulus Method on Pain and Physiological Parameters in Infants
This study aimed to investigate the impact of employing the multi-sensory stimulation technique by both the mother and the nurse on the pain and physiological responses of infants aged 2-6 months during vaccination.
- Trial name
- NCT06291519
- Testing
- Multi-sensory Stimulation Method-Mother Applying the Method to the Baby, Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby, Breastfeeding Applied Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain From Immunization
Reducing Pain in Four- to Six-month Old Infants Undergoing Immunization Using a Multi-modal Approach
The aim of this study is to answer the following question: In healthy infants aged four to six months undergoing routine immunization for diphtheria, tetanus, acellular pertussis, inactivated poliovirus and Haemophilus influenzae…
- Trial name
- NCT00954499
- Testing
- Tactile stimulation added to Standard care, Standard care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Procedural Pain, Pain-related Fear
Distraction Cards Versus Emotion-Regulation Toy Squeezing During Intramuscular Vaccination in Preschool Children
This single-center, parallel-group, randomized experimental study will compare the effects of two active non-pharmacological interventions - distraction-card use and emotion-regulation toy squeezing - on procedural pain and…
- Trial name
- NCT07669961
- Testing
- Distraction-Card Group, Emotion-Regulation Toy-Squeezing Group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Mersin University
Procedural Pain
A Test of the Effectiveness of a Device and Distraction for Pediatric Immunization Pain
The hypothesis of this study is that distraction cards used by the caretaker along with a vibrating cold pack placed proximal to the site of immunization will decrease the pain of routine pediatric immunizations when compared to…
- Trial name
- NCT01152489
- Testing
- Device: Buzzy
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- MMJ Labs LLC
Pain
Thermal Analgesia in Newborns
Newborns routinely experience pain associated with invasive procedures such as blood sampling, immunization, vitamin K injection, or circumcision.
- Trial name
- NCT00740298
- Testing
- sucrose, warmth
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain Due to Childhood Vaccination
Distraction and Vibration for Minimizing Pain During Childhood Vaccination
Vaccine pain control is one of the actions suggested to support the delivery of vaccines that are on a vaccine schedule, since pain and anxiety associated with vaccines are among the main reasons why children and their parents…
- Trial name
- NCT03540589
- Testing
- Buzzy specific vibration device, Distraction
- Where
- Brazil
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospital Nossa Senhora da Conceicao
Vaccination Pain Management
Rotavirus vs. Sucrose for Vaccine Injection Pain
This randomized trial will compare the analgesic effectiveness of oral rotavirus vaccine to sugar water for reducing vaccine injection pain in infants.
- Trial name
- NCT02174705
- Testing
- Sucrose, Rotavirus
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anna Taddio