Clinical trials: Vaccination Pain
Pain, Intramuscular Injection
The Effect of ShotBlocker on Injection Pain
Shotblocker is an effective approach to reduce injection pain. Generally, injection pain has been studied in children, but reducing injection pain in adults is an important issue.
- Trial name
- NCT05495542
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bornova No. 25 Mevlana Family Health Center
Child, Only
The Effect of the Helper Skin Tap Technique and Buzzy® During Vaccination
Aim: This randomised controlled experimental study was conducted to determine the effect of Helfer Skin Tap Technique and Buzzy® application on the pain level during measles-mumps-rubella-mumps (MMR) vaccine injection in…
- Trial name
- NCT06312228
- Testing
- Helfer Skin Tap, Buzzy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Immunization
Testing Educational Materials in a Paediatric Setting
Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain.
- Trial name
- NCT01713322
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke Sequelae, Chronic Pain
Transcraneal Magnetic Stimulation for Treatment of Non-nociceptive Pain in Chronic Diseases
Background: Chronic non-nociceptive or nociplastic pain and neurological sequelae following stroke are associated with substantial functional impairment and reduced quality of life.
- Conditions
- Stroke Sequelae, Chronic Pain, Fibromyalgia, Long COVID19
- Trial name
- FATMAGPAIN (NCT07888673)
- Testing
- Transcraneal Magnetic Stimulation (rTMS)
- Where
- 2 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Hospital Donostia
Syncope, Vasovagal
Presyncope (Syncope) Prevention Study
This study was a prospective, randomized clinical trial that was conducted in adolescents (10 through 14 years of age) receiving at least one recommended intramuscularly administered vaccine to evaluate the efficacy and…
- Trial name
- PS^2 (NCT04772755)
- Testing
- Buzzy® and Electronic Game
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Duke University
Vaccination Reaction, Vaccination Pain
CARD for Community Pharmacy Vaccinations
To integrate CARD in community pharmacy-led vaccinations and document impact on vaccine clients and pharmacy staff.
- Conditions
- Vaccination Reaction, Vaccination Pain, Community Pharmacy
- Trial name
- NCT06098703
- Testing
- CARD (Comfort Ask Relax Distract)
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain, Quality of Life
Simultaneous RZV and aIIV4 Vaccination
The overall aim of the study is to compare the safety of simultaneous Zoster Vaccine Recombinant, Adjuvanted (RZV) (SHINGRIX®) and Quadrivalent Influenza Vaccine, Adjuvanted (FLUAD®) versus simultaneous Zoster Vaccine…
- Conditions
- Pain, Quality of Life, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05007041
- Testing
- FLUAD® Quadrivalent, Fluzone® High-Dose Quadrivalent, SHINGRIX®
- Where
- 2 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain, Anxiety
Leveraging on Immersive Virtual Reality to Reduce Pain and Anxiety in Children During Immunization in Primary Care
Paediatric immunization is often associated with significant fear and anxiety among children and their parents. Their distress can greatly affect their future adherence to the immunization schedule and the acceptance of…
- Trial name
- NCT04748367
- Testing
- Virtual Reality Headset
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SingHealth Polyclinics
Procedural Pain
Parent Targeted Interventions in Vaccination Pain Management of Infants
The overall aim of this study is to investigate the feasibility, acceptability, preliminary effectiveness and sustainability of parent-targeted interventions for pain management during vaccination of infants.
- Trial name
- NCT03968432
- Testing
- MIAS&Q, Be Sweet to Babies Videos and Pamphlet
- Where
- Canada
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Vaccination
Virtual Reality vs. Standard-of-Care for Comfort During Immunizations in Children
Children need routine immunizations which can be a painful procedure associated with pain and anxiety. This is particularly true of children visiting the children's hospital to visit relatives during flu season.
- Trial name
- NCT03693469
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Procedural Pain, Child, Only
Effect of Acupressure on Interventional Pain in Infants
This study will be conducted to investigate the effect of acupressure, to be applied to the GallBladder (GB) 31 "Fengshi" acupuncture point before the vaccinations, on interventional pain caused by the vaccinations in infants.
- Trial name
- NCT05166551
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Breast Feeding
Non-Pharmacological Methods for Reducing Pain During Vaccination in Infants
Pain management in infants is a medical responsibility of all members of the healthcare team, and nurses hold a privileged role in this regard.
- Conditions
- Pain, Breast Feeding, Maternal Behavior
- Trial name
- NCT06886412
- Testing
- Maternal Holding Intervention Group, Breast Feeding Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Fear of Pain, Fear
Effect of Using Virtual Reality Goggles on Fear and Pain Level During Vaccination in Children
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using Virtual Reality Glasses reducing fear and pain during routine vaccination in children.
- Conditions
- Fear of Pain, Fear, Virtual Reality, Pain
- Trial name
- NCT06560320
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Musculoskeletal Pain, COVID-19
Muscular and Joint Symptoms in COVID-19 Patients: Insights From Syria
Observation study, shows the relation between musckeloskeletal symptoms with during and post Covid-19 infection, by asking participants questions about there age,job,which vaccination covid participants took, residual area…
- Trial name
- NCT06328595
- Where
- Syria
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Pain
Rapid Injection Technique Without Aspiration
This experimental, single-blind, randomized controlled trial study was conducted to compare the effect of the rapid injection technique without aspiration on pain level in the vaccination for the young adult students.
- Trial name
- NCT03723421
- Testing
- Rapid Injection Group Without Aspiration, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Pain
Thermal Analgesia in Newborns
Newborns routinely experience pain associated with invasive procedures such as blood sampling, immunization, vitamin K injection, or circumcision.
- Trial name
- NCT00740298
- Testing
- sucrose, warmth
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Individual Satisfaction, Pain Management
The Effect on Pain and Satisfaction of Two Different Non-Pharmacological Methods Used During Coronavirus (Covid-19) Vaccination
The aim of this study was to determine the effect on pain and satisfaction during the administration of Covid-19 vaccination of two different non-pharmacological methods: squeezing a stress ball and placing Buzzy® on the…
- Trial name
- NCT05514262
- Testing
- The stress ball, The Buzzy® device
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pain
Reduction of Immunization Discomfort in Children
A combination of topical anesthetic, plastic arm gripper, visual focusing task and hypnotic suggestions will reduce the discomfort associated with immunization of pre-kindergarten aged children.
- Trial name
- NCT00720824
- Testing
- Topical anesthetic and hypnotic distraction, Office routine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Berberich, F. Ralph, M.D.
Procedural Pain, Nursing Caries
The Effect of Mechanical Vibration and Helfer Skin Tap Technique on Procedural Pain in Infants During Vaccination
This study will be conducted to determine the effect of mechanical vibration and Helfer Skin Tap technique applied during intramuscular vaccinations on procedural pain level, crying time and procedure time in healthy infants.
- Conditions
- Procedural Pain, Nursing Caries, Pain, Acute
- Trial name
- NCT06454812
- Testing
- Mechanical vibration, Helfer skin tap technique (HSTT)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Pain, Fatigue
Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascular Disease
The coronavirus SARS-CoV-2 causing COVID-19 was pandemic since 2020. Vaccination is one of the most important measure to control the outbreak. The countries of the world started the vaccination since December, 2020.
- Conditions
- Pain, Fatigue, Headache, Myalgia
- Trial name
- NCT05033613
- Testing
- heart rate、arrhythmia、blood pressure、central body temperature (ear temperature) and blood oxygen saturation level.
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital