Clinical trials: Validation Study
Chest Trauma
Evaluating Validity of Clinical Criteria for Requesting Chest X-Rays in Trauma Patients
The purpose of this study is to identify the clinical criteria for requesting a chest x-ray in a patient with blunt trauma and its findings such as clinical signs with a high sensitivity could be used in a larger study to codify…
- Trial name
- NCT01134744
- Where
- 2 sites in Iran
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Maternal Behavior
Midwife-led Continuity and Satisfaction With Care - an Observational Case-Control Study in Palestine
This study investigate if a midwife-led continuity model of care in Palestine, had impact on rural women's satisfaction with care through the continuum of antenatal, intrapartum and postnatal period.
- Trial name
- NCT03863600
- Testing
- Midwife-led continuity of care
- Where
- Palestinian Territories
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Oncology
Validation of the GMFM-88 Scale and of the FAAP-O Scale in Pediatric Patients Affected by Cancer
The primary objective of this study is to validate the Gross Motor Function Measure Scale-88 (GMFM-88) on the Italian pediatric cancer population.
- Trial name
- FAAP-O (NCT04862130)
- Where
- 10 sites in Italy
- Volunteers
- 217 people
- Sponsor
- Associazione Italiana Ematologia Oncologia Pediatrica
Cardiopulmonary Bypass
Validation of Near Infrared Spectroscopy (NIRS) During Heart-Lung Bypass in Children
Non-invasive assessment of blood flow to organs has long challenged clinicians. Recently, near infrared spectroscopy (NIRS) has been recognized as a methodology that may achieve this goal.
- Trial name
- NIRS (NCT00745394)
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Genotyping Techniques
Spartan Cube CYP2C19 Method Comparison Study
The aim of the study is to demonstrate concordance (percent agreement) between results produced by the Spartan CYP2C19 system and bi-directional sequencing.
- Trial name
- NCT04473586
- Testing
- Spartan Cube CYP2C19 System
- Where
- Canada
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.
Asthma in Children
Leo Study Unstable Asthma
This is a prospective, observational study to investigate the agreement of the Leo device signal derivation with gold standard asthmatic testing in recently exacerbated asthmatic children.
- Trial name
- NCT05308277
- Testing
- Leo device monitoring
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- ResMed
Necrotizing Enterocolitis
A Biologic Validation of Biomarkers of Progressive NEC & Sepsis
Necrotizing enterocolitis (NEC) is a severe, sometimes life-threatening inflammation of the intestine that occurs most often in premature babies.
- Trial name
- NEC (NCT00588718)
- Where
- United States
- Volunteers
- 740 people
- Sponsor
- R. Lawrence Moss
Respiratory Rate
Sensor Validation Study - Quality Assurance
The respiratory rate is an important parameter in clinical medicine. It is defined as the number of breaths per minute. Currently this is measured at the bedside in clinical practice by counting the breaths, however the gold…
- Trial name
- NCT03306537
- Testing
- RespiraSense Respiratory Rate Monitor
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- PMD Solutions
Healthy
AQUAPed: Validation Study of AQUA© Questionnaire Modified for Childhood
The AQUA© questionnaire developed in 2008 is a validated tools for the screening of allergic diseases in adult athletes. The objective of the present study is to develop and validate a modified version of the AQUA© questionnaire…
- Trial name
- AQUAPed (NCT03286894)
- Where
- Italy
- Volunteers
- 1,264 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Electrolyte Disorder, Arrhythmia
Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting
The goal of this study is to compare the performance of a novel Point-of-Care Testing (POCT) dry electrolyte analyzer (P1) with the Nova Stat Profile pHOx Ultra Analyzer System (Nova) in an acute care setting.
- Conditions
- Electrolyte Disorder, Arrhythmia, Stroke
- Trial name
- NCT06726460
- Testing
- Nova Stat Profile pHOx Ultra Analyzer System(Nova), Novel POCT dry electrolyte analysis system(P1)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhujiang Hospital
Rectal Cancer, LARS - Low Anterior Resection Syndrome
Comparison of Six Different Machine Learning Methods With Traditional Model for Low Anterior Resection Syndrome After Minimally Invasive Surgery for Rectal Cancer -- Development and External Validation of a Nomogram : A Dual-center Cohort Study
Following thorough screening based on inclusion and exclusion criteria, patients from the two sizable medical centers were split up into two cohorts for this study.
- Trial name
- NCT07267767
- Testing
- nCRT, BMI, Distance from AV
- Volunteers
- 3,500 people
- Sponsor
- Northern Jiangsu People's Hospital
Dermatitis, Nevus
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
This study will evaluate whether digital photography is a reliable tool for diagnosing hand rashes, psoriasis and unusual moles.
- Conditions
- Dermatitis, Nevus, Psoriasis
- Trial name
- NCT00005781
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Cancer Institute (NCI)
Polyp of Colon
Artificial Intelligence (AI) Validation Study for Polyp Detection
Interventional prospective multicenter study: Polyp detection by an automated endoscopic tool as second observer during routine diagnostic colonoscopy
- Trial name
- NCT04378660
- Testing
- Artificial intelligence for polyp detection
- Where
- Belgium
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Nurse-Patient Relations, Professional Role
The Relationship Competences Guiding Tool
Aim: The aims of this study are: (1) to present the development, content validation and implementation study of the Relationship Competences Guiding Tool (RCGT); (2) to show some examples of how each of the items of the guide may…
- Conditions
- Nurse-Patient Relations, Professional Role, Narration
- Trial name
- NarratUN (NCT05528523)
- Testing
- Writing a clinical narrative
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Celiac Disease in Children
Validation of a New Innovative Method for Specific Marker Detection in Celiac Disease
Celiac disease (CD) is a common auto-immune disorder induced by gluten ingestion in genetically susceptible individuals (HLA-DQ2/DQ8).
- Trial name
- NCT06324539
- Testing
- Diagnostic Test: Rapid Intestinal anti-TG2 Assay
- Where
- 4 sites in Italy
- Volunteers
- 332 people
- Sponsor
- IRCCS Burlo Garofolo
Concussions, PCS
Predicting Persistent Postconcussive Problems in Pediatrics (5P)
Concussion, a mild traumatic injury common in children and adolescents, is a complex pathophysiological process affecting the brain.
- Trial name
- 5P (NCT01873287)
- Where
- 9 sites in Canada
- Volunteers
- 3,063 people
- Sponsor
- Children's Hospital of Eastern Ontario
Healthy Nurses, Educational Activities
The Study Focuses on Training Newly Employed Nurses With Two Groups Interventional (Simulation Training) & Control (Brochure) Group Using BLS -AHA 2020 Using Simulation, the Test Includes Pre-test & 2 Post-test Surveys to Assess Knowledge, Practice & Confidence Level.
The general objective of this study is to develop, validate and evaluate the effectiveness of simulation in basic life support training (SBLST) among newly employed nurses in Jordanian governmental hospitals; the study design is…
- Trial name
- BLS-NEN-HCP (NCT06001879)
- Testing
- Simulation in basic life support training (SBLST), standard treatment by using an AHA-BLS 2020 brochure
- Where
- Jordan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- yousef Shukry Mohammad Abu-Wardeh
Pediatrics, Neurological Abnormality
Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE)
The American Academy of Pediatrics defines infants at risk as those with preterm birth, special health care needs, family risk factors, and those at risk of early death.
- Conditions
- Pediatrics, Neurological Abnormality, Neurodevelopment Outcome
- Trial name
- BRIEF-HINE (NCT07182474)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Suicidal Ideation, Self-Injurious Behavior
Youth Suicide and Self-Harm Intervention: Clinical and Biological Outcomes Study
The goal of this clinical trial is to develop and evaluate youth-focused intervention programs for suicide and self-harm that are tailored to the psychological, developmental, and cultural characteristics of Korean adolescents…
- Conditions
- Suicidal Ideation, Self-Injurious Behavior, Suicide, Attempted
- Trial name
- SHIELD (NCT07395752)
- Testing
- Self-Harm Intervention and Education for Long-term Development (SHIELD) Program, General Mental Health Education
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine
Cystic Fibrosis (CF), CFTR-related Disorders
A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis
Sometimes it is very difficult to tell if someone has cystic fibrosis (CF), especially when they have rare CF genes. Without this certainty, they are unlikely to get the correct treatment so their health may be affected.
- Trial name
- ADVANCE-CFTR (NCT07402434)
- Testing
- Rectal Biopsy, Rectal biopsy taken opportunistically during endoscopy procedure for other reasons., Blood test for CFTR Genotyping
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust