Clinical trials: Validation Study
Scoliosis
Use of the Scolioscan for Quantitative Evaluation of Spinal Deformity - A Validity Study on Patients With Scoliosis
The purpose of the study is to investigate the validity of Scolioscan for quantitative assessment of curve severity in scoliosis using x-ray radiographs as the gold standard.
- Trial name
- NCT02581358
- Testing
- Scolioscan (Ultrasound imaging system)
- Where
- China
- Volunteers
- 952 people
- Sponsor
- Chinese University of Hong Kong
Acute Appendicitis
TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods
Acute appendicitis is the most common abdominal surgical emergency in children and a frequent cause of pediatric emergency department visits.
- Trial name
- TACTILE (NCT07479849)
- Testing
- Score-based appendicitis risk classification in teleconsultation
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Angers
Surfactant Deficiency Syndrome Neonatal, Respiratory Distress Syndrome in Premature Infant
Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment - Validation Study
The aim is to re-validate a FTIR spectroscopy test for measuring lung maturity/Respiratory Distress Syndrome (RDS) before conducting a RCT using this test to guide surfactant treatment of preterm infants.
- Trial name
- FAST2 (NCT05615428)
- Testing
- LS-ratio
- Where
- 3 sites in Denmark
- Volunteers
- 68 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intubation, Pediatric, Intubation; Difficult or Failed
Validation of the POGO Score for Classification of Videolaryngoscopy in Children - Post-hoc Analysis of the PeDiAC Study
It has been assumed that the percentage of glottic opening (POGO) score might enhance the classification of videolaryngoscopic tracheal intubation by offering a more objective rating of glottic exposure but studies in children…
- Conditions
- Intubation, Pediatric, Intubation; Difficult or Failed, Airway Management, Airway Complication of Anesthesia
- Trial name
- POGO-KIDS (NCT07115407)
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Volunteers, Study Focus: Blood Pressure Measures
Valid-B.Well BP25 Study
Prospective, single-center, single-arm, open, comparative, validation of a commercialized device, repeated measures accuracy study designed in accordance with the requirements of the ISO 81060-2:2018 AAMI/ESH/ISO Universal…
- Trial name
- NCT07340957
- Testing
- Blood pressure measurement
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- B.Well Swiss AG
Tumor, Malignancy
Validation Study of Pediatric Patient-Reported Outcomes
Survivors of childhood cancer often suffer treatment-related toxicities, including chronic health conditions, high symptom burden and emotional distress, and decremented functional status and quality of life.
- Trial name
- NCT03229837
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- St. Jude Children's Research Hospital
Soft Tissue Sarcoma, Osteosarcoma
Huntsman Biopsy Study
Bone and soft tissue sarcomas are currently classified based upon light microscopy supplemented by immunohistochemistry, but within many if not all of these tumor histologic types, considerable heterogeneity exists not only in…
- Trial name
- NCT00615329
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- State University of New York - Upstate Medical University
Kidney Failure, Acute, Renal Insufficiency
Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery
People who undergo coronary artery bypass grafting (CABG) or heart valve surgery may experience acute kidney injury (AKI) after their surgery.
- Trial name
- NCT00774137
- Where
- 8 sites in United States, Canada
- Volunteers
- 1,550 people
- Sponsor
- Yale University
Female Pelvic Examination
A Study to Test a New Pelvic Examination Assessment Tool
The purpose of this study is to show that a new assessment tool for pelvic examination is valid and reliable.
- Trial name
- PEAT (NCT01725581)
- Testing
- Observed Structured Assessment Tool in Pelvic Examination
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Vestibular Migraine
Health Belief Model Scale Development for Disability and Abilities in Vestibular Migraine Patients
Vestibular migraine (VM) is a neurological condition characterized by recurrent episodes of dizziness, imbalance, and migraine-related symptoms. Individuals' responses to health problems are influenced by their health beliefs.
- Trial name
- NCT07469748
- Testing
- Vestibular Migraine Education / Awareness Session
- Where
- Turkey (Türkiye)
- Volunteers
- 213 people
- Sponsor
- Istanbul Aydın University
Phenylketonuria (PKU) and Hyperphenylalaninemia
PheCheck™ Validation Study
The goal of this observational study is to evaluate the performance of the PheCheck™ test for the rapid detection of phenylalanine (Phe) from a fingerstick sample, in patients 1 year or older with phenylketonuria (PKU) or…
- Trial name
- NCT07551921
- Testing
- PheCheck, Dried Blood Spot Cards.
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Aptatek BioSciences, Inc
Visceral Leishmaniasis
Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation Study
Visceral leishmaniasis (VL) or kala azar is a neglected tropical disease(NTD) caused by protozoan parasites of the Leishmania donovani complex that are transmitted by phlebotomine sand flies.
- Trial name
- NCT06118749
- Testing
- Antigen detection Rapid Diagnostic Test prototype
- Where
- Kenya
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Motor Development, Infant, Premature, Diseases
Peabody Developmental Motor Scale-2 in 0 - 24 Months in Turkey
This study is the determination of the Turkish version of the Peabody Developmental Motor Scale-2 and its Turkish validity reliability in infants age between 0 - 24 months and to spread its use for evaluation in early…
- Trial name
- NCT04886310
- Testing
- Peabody Developmental Motor Scale II (PDMS-2)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ondokuz Mayıs University
Scleroderma
Cross-cultural Adaptation and Validation of the Localised Scleroderma Quality of Life Instrument (LoSQI) in Juvenile Localised Scleroderma (JLS)
This international study adapts and validates the Localised Scleroderma Quality of Life Instrument (LoSQI) for children with JLS, a rare condition causing hardened skin and tissue.
- Trial name
- LoSQI (NCT07908108)
- Where
- 33 sites in Argentina, Brazil and 17 more
- Volunteers
- 272 people
- Sponsor
- Istituto Giannina Gaslini
Pediatric Cancer
Cross-cultural Adaptation and Validation of the P-CIN for Chinese Pediatric Oncology Patients
The goal of this study was to conduct a cross-cultural adaptation of the P-CIN into the Chinese context, assess its psychometric properties, and determine the cut-off value of CIPN among Chinese pediatric oncology patients.
- Trial name
- NCT07053579
- Where
- 2 sites in Hong Kong
- Volunteers
- 313 people
- Sponsor
- The Hong Kong Polytechnic University
Hemoglobin, Cerebral Oxygenation
Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics
This study will enroll children and young adults who are scheduled to undergo planned heart surgery or a heart catheterization procedure while under general anesthesia.
- Conditions
- Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
- Trial name
- NCT07706140
- Testing
- Noninvasive hemoglobin monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Validation
Validity and Feasibility of Newborn Bed Monitoring Device - a Clinical Pilot Study
The aim of this clinical pilot study is to evaluate the validity, acceptability and usability of the newborn bed monitoring device among newborns, parents and healthcare professionals in hospital environment.
- Trial name
- NCT06679127
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Anna Axelin
ACL - Anterior Cruciate Ligament Deficiency
AI-Based Video Assessment of Anterior Knee Laxity
This prospective observational validation study aims to evaluate the accuracy and reliability of artificial intelligence-based video analysis for quantifying anterior knee laxity.
- Trial name
- AI-LAX (NCT07833605)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ASL Lecce
Coronavirus
Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry
Researchers are creating a real time COVID-19 registry of current ICU/hospital care patterns to allow evaluations of safety and observational effectiveness of COVID-19 practices and to determine the variations in practice across…
- Trial name
- COVID-19 (NCT04323787)
- Testing
- observational
- Where
- 4 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Mayo Clinic
Esophageal Cancer
Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus
RATIONALE: Questionnaires that measure quality of life may improve the ability to plan treatment for patients who have cancer of the esophagus.
- Trial name
- NCT00003321
- Testing
- psychosocial assessment and care, quality-of-life assessment
- Where
- 10 sites in Australia, France and 6 more
- Volunteers
- 370 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC