Clinical trials: Validation Study
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Measure Accuracy of Respiratory Rate
Respiratory Rate Validation Study
The purpose of this study is to conduct a Respiratory Rate accuracy validation on pediatrics population comparing the Gabi SmartCare Gabi Band to the Reference, an FDA cleared End Tidal Carbon Dioxide monitor (GE Datex- Ohmeda)…
- Trial name
- NCT05856422
- Testing
- Respiratory rate measure based on PPG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Athletic Injuries
Validity of an Upper Extremity Physical Performance Test Battery in Healthy Athletes
This project comprises two studies; a cross-sectional study and a prospective study. 1. The cross-sectional study aims to develop and validate a new sport-specific test battery (PROMs, analytical and physical performance tests)…
- Trial name
- VAL_PPT_H (NCT06153121)
- Testing
- Physical performance test - Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), Physical performance test - modified Closed Kinetic Chain Upper Extremity Stability Test (m-CKCUEST), Physical performance test - Seated Seated Single Arm Shot Put Test (SSASPT)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Ghent
Affective; Reaction, Pregnancy Related
Developing and Validating Digital Affective Patient Experience/Outcome Measure
The aim of the research project is to develop and validate a new digital measure of affective patient experience in maternal care.
- Conditions
- Affective; Reaction, Pregnancy Related, Validation Studies
- Trial name
- ETVa (NCT03337321)
- Where
- Finland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Post-stroke Depression
Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke
Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive…
- Trial name
- NCT07294274
- Testing
- Group patients based on whether they have been diagnosed with PSD.
- Where
- China
- Volunteers
- 488 people
- Sponsor
- Min Su
COVID-19
Bioaerosol Sampling Device (BSD) Clinical Study
The goal of this clinical trial is to learn about the bioaerosol sampling device (BSD) and how it can sample patient bioaerosols (breath) and patient's nares for the detection of COVID-19 viral particles in patients seeking to be…
- Trial name
- NCT06047067
- Where
- 6 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Cantor BioConnect, Inc.
Typhoid Fever
Commercial Typhoid Tests Validation Trial
Typhoid fever (typhoid) is an enteric bacterial infection caused by Salmonella enterica serovar Typhi (Salmonella Typhi; S. Typhi).
- Trial name
- NCT04801602
- Testing
- Rapid diagnostic tests
- Where
- 2 sites in Kenya, Pakistan
- Volunteers
- 3,091 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
CDKL5, CDKL5 Deficiency Disorder
International CDKL5 Clinical Research Network
Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments…
- Conditions
- CDKL5, CDKL5 Deficiency Disorder, CDD
- Trial name
- ICCRN (NCT05558371)
- Testing
- No intervention.
- Where
- 9 sites in United States, Australia
- Volunteers
- 1,000 people
- Sponsor
- University of Colorado, Denver
Fall Prevention
Validation Study of the Speedy Meyer Fall Scale for Determining the Fall Risk of the Paediatric Patient
Fall prevention is an essential element in ensuring safe care for paediatric patients. The first step in building a risk reduction programme is the adoption of an assessment tool to identify those most at risk at an early stage.
- Trial name
- NCT06311409
- Where
- 3 sites in Italy
- Volunteers
- 332 people
- Sponsor
- Meyer Children's Hospital IRCCS
Syncope
NICE Guideline 'Red Flags' to Predict Serious Outcome After Transient Loss of Consciousness
This study is designed to evaluate the accuracy of the National Institute for Health and Clinical Excellence (NICE) guideline 'red flags' to identify patients at high risk of short term serious outcome when presenting in the…
- Trial name
- NCT01498471
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intracranial Pressure
Validation of Non-Invasive Intracranial Pressure Estimation Using CPMX3 in the Periorbital Vein: A Feasibility Study in Pediatric Patients
Intracranial pressure (ICP) monitoring is indicated in a wide range of neurological diseases. The combination of a linear ultrasound array with an integrated pressure sensor into a single handheld probe (ICP Probe) enables the…
- Trial name
- VENUS-ICPxP (NCT07550361)
- Testing
- CPMX3 measurement
- Where
- United States
- Sponsor
- Compremium AG
Neurological Disorder
A Reliability and Validity Study: Urdu Version of Rivermead Extended Activities of Daily Life
The goal of this study is to translate and culturally adapt Rivermead Extended Activities of Daily Life into the Urdu language and to evaluate its reliability and validity in the Pakistani neurological rehabilitation population.
- Trial name
- NCT05425186
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Congenital Heart Diseases, Cardiac Diseases
An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function
This project aims to evaluate a new cardiac MRI technique called the Free-Running Framework (FRF), which could simplify and accelerate the process of acquiring cardiac images.
- Trial name
- FAST-CMR (NCT07613398)
- Where
- 20 sites in United States, Australia and 8 more
- Volunteers
- 300 people
- Sponsor
- Matthias Stuber
Anorectal Malformations
Baylor Continence Scale Validity in Anorectal Malformation
The aim of this study is to evaluate the validity and reliability of the Baylor Continence Scale in Turkish-speaking children diagnosed with anorectal malformations.
- Trial name
- NCT07029984
- Testing
- Baylor Continence Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Izmir Bakircay University
Low Anterior Resection Syndrome, Radiotherapy
Development and Validation of The Post-RT LARS Prediction Model (PORTLARS)
Bowel dysfunction is common after a restorative rectal cancer resection. Neoadjuvant radiotherapy is an influential factor that impairs bowel function and quality of life.
- Conditions
- Low Anterior Resection Syndrome, Radiotherapy, Rectal Cancer
- Trial name
- PORTLARS (NCT05129215)
- Testing
- Questionnaire
- Where
- China
- Volunteers
- 901 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Obstructive Sleep Apnea
Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.
The goal of this observational study is to characterize the performance of the SleepView+ home sleep test system for the evaluation of moderate to severe obstructuve sleep apnea (OSA) in adult and pediatric patients (ages 12 and…
- Trial name
- NCT07476313
- Testing
- SleepView+
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beacon Biosignals
Postoperative Complications
Derivation and Validation of the Extended Care (Ex-Care) Model II
The goal of this study is to develop a novel surgical risk stratification tool designed to adults operated in Brazil. The main question it aims to answer is: •Is the Extended Care (Ex-Care) II model a good tool to assess the risk…
- Trial name
- Ex-CareII (NCT05796024)
- Where
- Brazil
- Volunteers
- 107,372 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Coronary Artery Disease
Validation of a Vital Signs Monitoring Wristband
Today, continuous monitoring of vital signs remains a challenge since it generally requires the patient to be connected to multiple wired sensors, which restricts patient mobility in the intra-mural setting and complicates home…
- Trial name
- MULTI-VITAL (NCT05566886)
- Testing
- Continuous measurement of photoplethysmography at the wrist
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Corsano Health B.V.
The Study Focuses to Find the Intrarater Reliability, Test-retest Reliability and Validity of 10 Meters Walk Test Among Middle School Going Children
Reliability and Validity of 10 Meters Walk Test Among Children
Timed Motor Function Tests (TMFTs) determined the walking abilities of an individual. During Covid-19 pandemic direct observation may not be feasible to record Timed motor function in children.
- Trial name
- NCT05314452
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Patient Safety, Intraoperative Complications
Validation Study of ClassIntra®
Whereas there are several validated systems for reporting postoperative complications, there are only a few and not prospectively validated systems for reporting intraoperative complications.
- Conditions
- Patient Safety, Intraoperative Complications, Postoperative Complications, Risk Management
- Trial name
- ClassIntra® (NCT03009929)
- Testing
- Observational study
- Where
- 18 sites in United States, Australia and 10 more
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Basel, Switzerland