Clinical trials: Vascular Function
Congenital Heart Disease, Pulmonary Hypertension
MRI and Computational Simulation Cardiology Study
The purpose of this study is to (1) quantify cardiovascular anatomy and physiology using magnetic resonance imaging under both resting and exercise conditions in patients who have congenital heart disease and in age-matched…
- Trial name
- NCT03149341
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Hypertension, Pre-Hypertension
Modifying Dietary Behavior in Adolescents With Elevated Blood Pressure
The purpose of this study is to examine the long term effects of a 24-week clinically-based behavioral nutrition intervention emphasizing the DASH diet compared to routine nutrition care on changing diet quality, blood pressure…
- Trial name
- DASH-4-Teens (NCT00585832)
- Testing
- DASH-4-Teens, Routine Care
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Cincinnati
Persistent COVID-19, Quality of Life
Vascular Structure, Vascular Function and Vascular Aging in Adults Diagnosed With Persistent COVID
The ICOPER study aims to analyze the structure, vascular function, vascular aging and determining factors in 300 adults diagnosed with Persistent Covid in the field of Primary Health Care.
- Conditions
- Persistent COVID-19, Quality of Life, Lifestyles, Arterial Stiffness
- Trial name
- ICOPER (NCT05819840)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Lymphedema, Lymphatic Disorders
Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders
The purpose of this study is to demonstrate the feasibility of near-infrared fluorescence imaging in subjects with acquired or hereditary lymphedema, in subjects with lipidema and other lymphovascular disorders and in normal…
- Conditions
- Lymphedema, Lymphatic Disorders, Lipedema, Vascular Malformation
- Trial name
- NCT00833599
- Testing
- NIRFLI with ICG
- Where
- 3 sites in United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke
After stroke, patients frequently suffer from arm or hand weakness. There are numerous rehabilitation methods to stimulate recovery, amongst which mirror therapy (MT).
- Trial name
- MT (NCT02949609)
- Testing
- Mirror Therapy, Control Therapy
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Geneva
Cardiovascular Diseases, Heart Diseases
Mental Stress, Autonomic Function, and Heart Disease
To examine the vagal, vascular sympathetic, and mechno-structural components of baroreflex regulation in coronary artery disease (CAD) patients and healthy age-matched controls during rest and acute laboratory stress.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005524
- Sponsor
- Hebrew SeniorLife
Hypotension, Fontan Physiology
The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology
The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures.
- Trial name
- NCT04463394
- Testing
- Vasopressin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Healthy, Hypercholesterolemia
The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic Patients
A layer of cells called the endothelium line the walls of blood vessels. These cells produce substances that control the tone of blood vessels and thus control blood flow through the vessel.
- Conditions
- Healthy, Hypercholesterolemia, Hypertension
- Trial name
- NCT00001742
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stroke
Effect of Segmental Muscle Vibration on Upper Extremity Functional Ability Post Stroke
Background and objective: Upper extremity functional impairments are common consequences post stroke. The aim of this study was to investigate the influence of Segmental muscle vibration (SMV) application along with supervised…
- Trial name
- NCT03419793
- Testing
- segmental vibration device, physical therapy exercises
- Volunteers
- 37 people
- Sponsor
- University of Rome Tor Vergata
Diabetes Mellitus, Type 1
Influence of Vitamin D on Vascular Function in Adolescents and Young Adults With Type 1 Diabetes
The purpose of this study is to study the role of low vitamin D levels on the health of blood vessels or vascular function in adolescents and young adults with type 1 diabetes.
- Trial name
- NCT01103817
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- The Hospital for Sick Children
Coronary Artery Disease, Type 2 Diabetes Mellitus
Arginase Inhibition in Ischemia-reperfusion Injury
The present project is designed to test the hypothesis that arginase contributes to endothelial dysfunction induced by ischemia-reperfusion in patients with coronary artery disease.
- Trial name
- NCT02009527
- Testing
- N-hydroxy-nor-arginine, NaCl
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Brain Tumor, Brain Pathology
Can we Use Resting-state fMRI and CSD Fiber Tractography for Presurgical Mapping?
This prospective study aims to investigate and validate the use of resting-state functional MRI (rs-fMRI) and high angular resolution diffusion imaging (HARDI), specifically constrained spherical deconvolution (CSD) tractography…
- Conditions
- Brain Tumor, Brain Pathology, Epilepsy, Vascular Malformations, Brain
- Trial name
- NCT06040580
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Coronary Disease
Hostility and Coronary Risk--Role of Weak Vagal Function
To determine whether deficient vagal antagonism of sympathetic nervous system (SNS) actions on the heart contributed to increased coronary heart disease risk in hostile persons.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00005337
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Trephined Syndrome, Sinking Skin Flap Syndrome
Prevalence of Trephined Syndrome After Decompressive Craniectomy
Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy.
- Conditions
- Trephined Syndrome, Sinking Skin Flap Syndrome, Traumatic Brain Injury, Stroke
- Trial name
- TS (NCT03186157)
- Testing
- Decompressive craniectomy, Cranioplasty
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Geneva
Stroke
Rehabilitation Team Functioning and Patient Outcomes
The purpose of the study is to determine if 1. Rehabilitation staff can be trained to work better together as a team; and 2. Better team work improves patient outcomes.
- Trial name
- NCT00237757
- Testing
- Information feedback
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- US Department of Veterans Affairs
Subacute Stroke, Balance Deficits
Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients
This study examines how Inspiratory Muscle Training (IMT) combined with the Abdominal Drawing-In Maneuver (ADIM) affects balance, gait, and breathing in stroke patients.
- Trial name
- NCT06838871
- Testing
- Inspiratory Muscle Training (IMT) with Abdominal Drawing-In Maneuver (ADIM) training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Sahmyook University
Stroke
Effect of Qigong on Balance, Fall Efficacy, Wellbeing of People With Stroke in Hong Kong
The purpose of this study is to compare the effects of qigong practice with fitness exercise on balance, fall-efficacy, physical functions, psychological wellbeing and quality of life of stroke survivors.
- Trial name
- NCT02999464
- Testing
- Qigong, Fitness exercise
- Where
- Hong Kong
- Volunteers
- 58 people
- Sponsor
- The Hong Kong Polytechnic University
Peripheral Arterial Disease, Claudication
Effects of Passive Muscle Stretching on Vascular Function and Symptoms of PAD
Patients with peripheral arterial disease often have walking impairment due to insufficient oxygen supply to lower extremity skeletal muscle.
- Trial name
- NCT03288181
- Testing
- Muscle Stretch
- Volunteers
- 13 people
- Sponsor
- Tallahassee Research Institute, Inc.
Cystic Fibrosis
Fitness, Body Composition, Physical Activity and Sleep Patterns in People With Cystic Fibrosis on Modulator Therapy.
Cystic fibrosis (CF) is the most common inherited condition in the United Kingdom, affecting approximately 10,837 people. It is well recognised that regular exercise is clinically important for people with CF.
- Trial name
- Understand-CF (NCT05857709)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
End-Stage Renal Disease
Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis
Adiponectin, an adipose tissue derived protein, with anti-inflammatory properties that is secreted from adipose tissue, is associated with insulin resistance.
- Trial name
- NCT00155363
- Testing
- conventional artificial kidney (AK) vs. high flux AK
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital