Clinical trials: Ventilated Patients
Mechanically Ventilated Children Admitted to the Pediatric Intensive Care Unit
Impact of Sedation Practices on Clinical Outcomes Among Mechanically Ventilated Children
evaluate the impact of sedation adequacy on clinical outcomes in mechanically ventilated children admitted to the pediatric intensive care unit (PICU).
- Trial name
- ISPMVC (NCT07821268)
- Testing
- no need
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yasmine Ahmed Abdelrahman
Pneumothorax
Heart Rate Variability in Pneumothorax
Changes in heart rate variability in anesthetized, ventilated patients undergoing tension pneumothorax for thoracoscopic cervical sympathectomy
- Trial name
- NCT03537417
- Testing
- for thoracoscopic ablation of cervical sympathetic chain
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Respiratory Insufficiency
Assessing Diaphragm Muscle Inactivity in Mechanically Ventilated ICU Patients
Background: Mechanical ventilation is a life saving intervention in patients with acute respiratory failure, for instance, due to infection or trauma.
- Trial name
- DIVIP (NCT02434016)
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Unity Health Toronto
Fluid Therapy, Vasopressor Therapy
Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients
The goal of this woldwide observational study is to investigate various aspects of fluid and vasopressor therapy in critically ill invasively ventilated patients.
- Conditions
- Fluid Therapy, Vasopressor Therapy, Critical Illness, Invasive Ventilation
- Trial name
- PRoFLUID (NCT05968066)
- Where
- Netherlands
- Volunteers
- 2,508 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pain, Pediatric ALL
Validation of the ANI in Perpubescent Patients in Pediatric Intensive Care Unit.
The ANI monitor is a medical device allowing to measure the response of the autonomic nervous system to a painful stimulus. In the pediatric population under general anesthesia, the ANI score can detect failure of locoregional…
- Trial name
- ANI-EP (NCT04913038)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Nurse's Role, Bispectral Index
Nurse-Led BIS-Guided Sedation Protocol in Pediatric Intensive Care
Pediatric intensive care sedation is traditionally based on subjective clinical scales. Bispectral Index (BIS) monitoring provides an objective EEG-based assessment of sedation depth.
- Conditions
- Nurse's Role, Bispectral Index, Pediatric Sedation
- Trial name
- NCT07252024
- Testing
- BIS-Guided Sedation Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Intensive Care Units, Pediatric, Anesthetics, Inhalation
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
The goal of a pilot study is to test a study plan to see if it is appropriate for a larger study. This study plan is looking at whether the use of inhaled sedatives (medications that help people be calm and sleep) can reduce…
- Conditions
- Intensive Care Units, Pediatric, Anesthetics, Inhalation, Mechanically Ventilated, Critically Ill Children
- Trial name
- ABOVE (NCT05867472)
- Testing
- Isoflurane Inhalant Product
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Otitis Media
Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy
The purpose of this study is to compare the difference in effect of three clinically common methods of providing pain medication during surgery for ventilating tubes placed for recurring ear infections.The methods are fentanyl…
- Trial name
- NCT01244126
- Testing
- Intranasal fentanyl, morphine IM, IV morphine
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Baylor College of Medicine
Acute Brain Injury, Post-neurosurgical Status
High-Flow Nasal Cannula After Extubation in Acute Brain Injury
Patients with acute brain injury after neurosurgery are at increased risk of extubation failure after removal of the endotracheal tube.
- Conditions
- Acute Brain Injury, Post-neurosurgical Status, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07664085
- Where
- Vietnam
- Volunteers
- 285 people
- Sponsor
- Bach Mai Hospital
Coronavirus, ARDS, Human
External Dead Space in Ventilated COVID-19 Patients
The objective is to investigate the efficacy of volumetric capnography to detect changes in dead space, CO2 elimination and shape factor parameters before and after disconnection of external dead space in ventilated COVID-19…
- Trial name
- NCT04424082
- Testing
- Removal of dead space filter
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Hemodynamic Instability
Pulse Pressure Variation Helps to Predict Fluid Responsiveness in Patients Ventilated With Low Tidal Volumes
Objective: To determine the value of pulse pressure variation (ΔRESPPP) to predict fluid responsiveness in patients ventilated with low tidal volumes (VT), and to investigate whether a lower ΔRESPPP cut-off point should be used…
- Trial name
- NCT01569308
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mechanical Ventilation Complication
Mechanical Ventilator Weaning in Chronically Ventilated Patients
Mechanical ventilation is a commonly used life-saving hospital procedure for patients with severe breathing difficulty. Some patients have difficulty separating from the ventilator and need to be removed gradually.
- Trial name
- NCT06976554
- Testing
- weaning
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, Los Angeles
Respiration, Artificial
Feasibility of Ventilation Detection Via Standard Defibrillator Pads in Mechanically Ventilated Pediatric Patients
This study is a prospective, observational case series of a convenience sample of mechanically ventilated pediatric patients in the Pediatric ICU, Progressive Care Unit and Operating Room at the Children's Hospital of…
- Trial name
- Vent Detection (NCT00628875)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital of Philadelphia
Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections
Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients
Given the possible prognostic relationship between exhaled breath condensate pH and clinical symptoms, it is quite plausible that exhaled breath condensate pH can prove useful in the intensive care unit.
- Conditions
- Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections, Pneumonia, Acute Lung Injury
- Trial name
- NCT00429637
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Virginia
Pediatric Acute Respiratory Distress Syndrome (PARDS), Pediatric Respiratory Diseases
IPV and Lung Compliance in Invasively Ventilated Children
The goal of this observational study is to determine if Intrapulmonary Percussive Ventilation (IPV) improves lung compliance in children receiving conventional invasive mechanical ventilation.
- Conditions
- Pediatric Acute Respiratory Distress Syndrome (PARDS), Pediatric Respiratory Diseases, Lung Compliance
- Trial name
- NCT06836050
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health