Clinical trials: Ventilation
Anxiety
Respiratory Dysregulation and Breathing Training in Anxious Outpatients
This study will explore respiratory dysregulation in anxious outpatients and examine the effect of breathing training with biofeedback for those anxious patients.
- Trial name
- NCT00108277
- Testing
- Breathing Training-Raise CO2, Breathing Training- Lower CO2
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cough, Tracheal Extubation
Extubation in Pediatric Patients: Proactive or Passive?
Smooth extubation process can reduce the complications in recovery time. This study aimed to investigate what is the better time to extubation when children is breathing spontaneously and adequately: waiting until children have…
- Trial name
- NCT04432701
- Testing
- proactive extubation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Obstructive Sleep Apnea, Malocclusion
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
This research aims to provide pediatric patients with polysomnography (a sleep study) before and after orthodontic treatment to determine if the extraction of upper premolars for treating excessive overjet results in an increase…
- Trial name
- NCT04946201
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohamed Bazina
Respiratory Distress Syndrome In Premature Infants
Successful Extubation and Noninvasive Ventilation in Preterm ≤ 1500g Terms
Noninvasive ventilation has been used in preterm newborn with respiratory distress syndrome in an attempt to assist failure extubation.
- Trial name
- NCT02396693
- Testing
- NIPPV, Bubble NCPAP, Ventilator NCPAP
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Mechanical Ventilation Complication, Pneumonia
Mechanically Ventilated Children and Pacifiers
Mechanical ventilation is a life support system developed to support or restore normal lung functions. Children who are connected to mechanical ventilator, separation from family in intensive care environment, getting away from…
- Conditions
- Mechanical Ventilation Complication, Pneumonia, Bronchiolitis
- Trial name
- NCT05566184
- Testing
- Modified pacifier
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Premature Birth
ADMA and Mechanical Ventilation in Preterm Infants
The purpose of this study is to study the relation between mechanical ventilation and ADMA concentrations at birth.
- Trial name
- NCT00460044
- Volunteers
- 35 people
- Sponsor
- Amsterdam UMC, location VUmc
Respiratory Distress Syndrome
A Multi-center Trial to Determine if Curosurf® Reduces the Duration of Mechanical Ventilation in Very Preterm Infants
The purpose of this study is to see if a medication called Curosurf can reduce the length of time that small premature babies with Respiratory Distress Syndrome (immature lungs) or RDS, stay on the ventilator, as compared to the…
- Trial name
- NCT01709409
- Testing
- Curosurf-Group1, BLES-group 2
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Ottawa Hospital Research Institute
Cough
Efficacy & Tolerability of a Specific Plantain,Thyme and Honey Cough Syrup vs Placebo in Child Cough Due to Common Cold
Cough is a life saving reflex, therefore it is important, especially in pediatrics, to calm cough spells without sedating the reflex.
- Trial name
- NCT02486835
- Testing
- Cough syrup for adults and children
- Where
- 4 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Clalit Health Services
Premature Birth, Respiratory Distress Syndrome, Newborn
Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants
Strategies to prevent lung injury, facilitate lung development, and to support the preterm infant's capacity to breathe are decisive.
- Trial name
- NCT04333563
- Testing
- CPAP, NIV NAVA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Respiration
Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care
The purpose of this study is to study whether neurally adjusted ventilatory assist (NAVA) provides advantages over current methods in detecting patients own breathing efforts in pediatric and neonatal ventilatory care.
- Trial name
- NCT00893087
- Testing
- Triggering mode of the ventilator, Triggering method of the ventilator
- Where
- Finland
- Volunteers
- 18 people
- Sponsor
- University of Oulu
Tonsillitis Chronic, Tonsillitis Recurrent
The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
- Conditions
- Tonsillitis Chronic, Tonsillitis Recurrent, OSA - Obstructive Sleep Apnea
- Trial name
- NSAIDs (NCT07035314)
- Testing
- Dexamethasone, NSAIDs, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Cerebral Palsy
The Effects of Protocolized Breathing Exercises on Pulmonary Function in Adolescents With Cerebral Palsy.
This multicenter randomized controlled pilot trial evaluates whether an 8-week protocolized breathing exercise program improves pulmonary function and quality of life in adolescents and young adults with cerebral palsy.
- Trial name
- NCT07873593
- Testing
- Protocolized breathing exercises
- Where
- Hungary
- Volunteers
- 360 people
- Sponsor
- Semmelweis University
Respiratory Insufficiency, Respiratory Failure
Cross-over Comparison of the V60 System to Other Bi-Level Noninvasive Ventilators
The purpose of this study is to compare a new noninvasive ventilator to existing ventilators already used for patient care.
- Trial name
- NCT00817804
- Testing
- Use of the V60 Mask Ventilator
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Respironics, California, Inc.
Respiratory Function Tests，Heart Function Tests, Cardiopulmonary Function
Xiangya Cardiopulmonary Health and Disease Cohort
Xiangya Cardiopulmonary Health and Disease Cohort (XY-CPHDC) is a non-intervention study grounded in real-world data. It is designed as a bidrectional clinical cohort combined retrospective and prospective design, in order to…
- Trial name
- XY-CPHDC (NCT06972784)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
ECMO Outcomes, Respiratory Failure (Pediatric Patients)
ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under…
- Conditions
- ECMO Outcomes, Respiratory Failure (Pediatric Patients), Malignancies, Hematologic, Solid Tumor Malignancies
- Trial name
- NCT07712835
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Respiratory Distress Syndrome (ARDS)
Turning Ratios Into Prognosis: Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as Powerful Predictors of ARDS in Pediatric Burn Patients: A Prospective Evaluation
The aim of this study is to evaluate the role of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as predictors for development of ARDS in pediatric burn patients.
- Trial name
- NCT07414056
- Testing
- Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Breathing Stop
Carbon Dioxide (CO2) Measurement With a CO2/O2 Guedel Airway
This trial compares capnographic signals using a modified CO2/O2 Guedel airway with a CO2/O2 nasal cannula without and with oxygen supply in sedated children aged 4 - 24 months.
- Trial name
- NCT03637257
- Testing
- modified Guedel airway
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obstructive Sleep Apnea, Cleft Palate
Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate
The craniofacial abnormalities found in infants and children with cleft palate (CP) lead to increased risk of obstructive sleep apnoea (OSA).
- Trial name
- SLUMBRS2 (NCT04478201)
- Testing
- back sleep positioning, side sleep positioning
- Where
- 11 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- Manchester University NHS Foundation Trust
Acute Respiratory Distress Syndrome (ARDS)
The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial
What is the effect of early high frequency oscillation (HFO) versus a lung-protective conventional ventilation (CV) strategy (using HFO only as rescue therapy), on all-cause hospital mortality among patients with severe early…
- Trial name
- OSCILLATE (NCT01506401)
- Testing
- SensorMedics 3100B High Frequency Oscillatory Ventilator, Lung Protective Ventilation
- Where
- 38 sites in United States, Canada and 3 more
- Volunteers
- 548 people
- Sponsor
- Canadian Critical Care Trials Group
ROHHAD, Rapid-Onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation
International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation (ROHHAD) Registry
The Center for Autonomic Medicine in Pediatrics (CAMP) has collaborated with doctors from around the world to build the first International ROHHAD (Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic…
- Trial name
- NCT03135730
- Testing
- ROHHAD
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Ilya Khaytin
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