Clinical trials: Ventriculoperitoneal Shunt
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Hydrocephalus, Shunt Malfunction
Role of Endoscopic Third Ventriculostomy in Management of Malfunctioning Ventriculoperitoneal Shunt
The aim of this study is to analyze our experience in management of malfunctioning ventriculoperitoneal shunt by using endoscopic third ventriculostomy (ETV).
- Trial name
- NCT06341946
- Testing
- Endoscopic third ventriculostomy
- Volunteers
- 30 people
- Sponsor
- Sohag University
Idiopathic Normal Pressure Hydrocephalus
A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus
In treating idiopathic normal pressure hydrocephalus with a shunt there is always a risk of underdrainage or overdrainage. The hypothesis is tested whether treatment of patients with an adjustable valve preset at the highest…
- Trial name
- NCT01570257
- Testing
- lowering of the performance level of an adjustable Strata valve in a ventriculoperitoneal (VP) shunt for treating idiopathic normal pressure hydrocephalus
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Erasmus Medical Center
Ventriculoperitoneal Shunt, Trans Fontanelle US
Insertion of Frontal Ventricular Catheter of VP Shunt in Congenital Hydrocephalus Guided by Trans Fontanelle Ultrasound
The Aim of This Study Is To Evaluate The Role Of Ultrasound In Decreasing Rate Of Proximal Obstruction In Frontal VP Shunt
- Conditions
- Ventriculoperitoneal Shunt, Trans Fontanelle US, Congenital Hydrocephalus
- Trial name
- NCT06664372
- Testing
- Trans fontanelle US Guided VP Shunt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cerebrospinal Fluid Shunts, Ventriculoperitoneal Shunt
Ceftaroline Diffusion Into Cerebrospinal Fluid of Children
Ceftaroline fosamil is an intravenous (IV) drug that belongs to a group of antibiotics called cephalosporins . Antibiotics are drugs used to treat infections.
- Trial name
- NCT02600793
- Testing
- Ceftaroline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Basim Asmar
Hydrocephalus
Study of Shunt Flow Under Different Valve Settings Using a Wireless Sensor
Hydrocephalus is commonly treated with a cerebrospinal fluid (CSF) shunt, a device that drains excess fluid from the brain. However, shunts can stop working over time, and determining whether fluid is flowing through a shunt can…
- Trial name
- NCT07679035
- Testing
- Rhaeos Shunt Monitoring System (RSMS), ShuntCheck III
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Rhaeos, Inc.
Communicating Hydrocephalus
Third Ventriculostomy Versus Shunt for Children With Hydrocephalus
Ventriculoperitoneal shunts are the standard of care for patients with communicating hydrocephalus, but they have a high failure rate - up to 40% fail within 1 year and 50% fail within 2 years.
- Trial name
- NCT01801267
- Testing
- Endoscopic third ventriculostomy (ETV), Ventricular shunt
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Hydrocephalus
Noninvasive Intracranial Pressure and Hydrocephalus Patients
Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries.
- Trial name
- NCT02404740
- Testing
- Pulse oximetry
- Volunteers
- 163 people
- Sponsor
- University of Colorado, Denver
Signs or Symptoms of Shunt Failure
The Use of Shunt Tap in Assessing Ventriculoperitoneal (VP) Shunt Malfunction
The objective of the study is to test the sensitivity and specificity of a shunt tap to predict shunt failure.
- Trial name
- NCT00205088
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Hydrocephalus
A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor
Hydrocephalus is commonly treated with a cerebrospinal fluid (CSF) shunt, a device that drains excess fluid from the brain. However, shunts can stop working over time, and determining whether fluid is flowing through a shunt can…
- Trial name
- NCT07815314
- Testing
- Rhaeos Shunt Monitoring System (RSMS), ShuntCheck III
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Rhaeos, Inc.
Intraventricular Hemorrhage, Premature Infants
Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome
Intraventricular hemorrhage and its resultant post-hemorrhagic hydrocephalus are significant risk factors for the development of neurodevelopmental delays in preterm infants.
- Trial name
- NCT00957840
- Testing
- NIRS, aEEG, and CSF concentration of biomarkers
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Utah
Hydrocephalus in Children
The Effect of Education Given to Parents of Children With Ventriculoperitoneal Shunt on Their Anxiety and Self-efficacy
This study aims to evaluate the effect of tele-education given to parents of children with ventriculoperitoneal shunt on their anxiety and self-efficacy.
- Trial name
- NCT06313879
- Testing
- Tele-education and Counseling Program
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Pamukkale University
Developing the ABEP-H, Determining the Effect of ABEP-H
The Effect of an Avatar-Based Education Program on Shunt Complications and Parents' Knowledge and Care Skills
Hydrocephalus is a common childhood neurosurgical disease. Ventriculoperitoneal (VP) shunt is usually used in the treatment of hydrocephalus. However, VP shunt may have some complications.
- Trial name
- NCT05370131
- Testing
- Avatar-Based Education Program in Hydrocephalus (ABEP-H)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hydrocephalus in Children
Precision Surgery for Pediatric Hydrocephalus: VPS vs. ETV With ML-Guided Prediction
Study type: Multicenter retrospective cohort study with prospective validation Primary purpose: To determine whether an individualized, imaging-guided treatment algorithm Ventriculoperitoneal shunt (VPS) vs endoscopic third…
- Trial name
- VPS ETV ML (NCT07330206)
- Testing
- MRI-Guided Precision Shunt or ETV Strategy
- Where
- China
- Volunteers
- 800 people
- Sponsor
- West China Hospital
Hydrocephalus, Normal Pressure, Ventriculomegaly, Cerebral
Volumetrics and Proteomics in Shunted Normal Pressure Hydrocephalus
Idiopathic normal pressure hydrocephalus (=iNPH) is a condition with disturbed circulation of cerebrospinal fluid (=CSF) causing symptoms such as balance and gait disorders, urinary incontinence and cognitive impairment in…
- Conditions
- Hydrocephalus, Normal Pressure, Ventriculomegaly, Cerebral, Shunt; Complications, Hydrocephalus Acquired
- Trial name
- LiNPH (NCT04785560)
- Testing
- Initial shunt setting post-operatively of the Certas Plus shunt valve.
- Where
- Sweden
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Hydrocephalus
HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants
Hydrocephalus is a potentially debilitating neurological condition that primarily affects babies under a year of age and has traditionally been treated by inserting a shunt between the brain and the abdomen.
- Trial name
- ESTHI (NCT04177914)
- Testing
- Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization (ETV+CPC), Ventriculoperitoneal Shunt
- Where
- 21 sites in United States, Canada
- Volunteers
- 165 people
- Sponsor
- University of Utah