Clinical trials: Vesicoureteral Reflux
Urinary Tract Infections
Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a Previous Urinary Tract Infection
Our hypothesis is that long-term antimicrobial prophylaxis does not reduce the recurrence of infection and the risk of appearance of kidney scars in children with a documented previous upper UTI.
- Trial name
- NCT00156546
- Testing
- antibiotic to reduce the recurrence of infection
- Where
- 16 sites in Italy
- Volunteers
- 660 people
- Sponsor
- University of Padova
Urologic Diseases, Urogenital Disease
VR to Reduce Pain and Anxiety During GU Scans
This study aims to test the effectiveness of virtual reality (VR) in reducing pain and anxiety in children undergoing voiding cystourethrograms (VCUG) at Children's Hospital Los Angeles (CHLA).
- Conditions
- Urologic Diseases, Urogenital Disease, Vesico-Ureteral Reflux
- Trial name
- NCT04251988
- Testing
- Oculus Go VR
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Pediatric Urology
Diagnostic Performance of PIC Cystogram vs VCUG in Children
The goal of this interventional diagnostic clinical trial is to evaluate and compare the diagnostic effectiveness of PIC cystography and voiding cystourethrography (VCUG) for the detection of vesicoureteral reflux (VUR) in…
- Trial name
- NCT07334821
- Testing
- PIC cystography, VCUG
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tarik Emre Sener
Vesicoureteral Reflux
DVD-Based Training Program in Self-Hypnosis for Children
The proposed study is designed to utilize a self-hypnosis DVD home-training program for parents to use with their children to teach self-hypnosis techniques for inducing relaxation and hypnotic analgesia.
- Trial name
- VCUG (NCT01483105)
- Testing
- DVD Self-Hypnosis Training Program
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Pyelonephritis, Renal Scars
A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux
The aim of this study is to assess the effectiveness of antibiotic prophylaxis in preventing pyelonephritis and in avoiding the appearance of new scars in a sample of children under 36 months with vesico-ureteral reflux (VUR).
- Trial name
- NCT00382343
- Testing
- Sulfamethoxazole/trimethoprim
- Where
- 7 sites in Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS Burlo Garofolo
Vesicoureteral Reflux
Parent Education and Medical Play: A Comparison of Psychological Preparation Strategies for Voiding Cystourethrogram
Hypothesis: The use of parent education and medical play will be able to reduce patient discomfort with potential uncomfortable medical procedures.
- Trial name
- NCT01578291
- Testing
- Parental information, Play therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Johns Hopkins University
Vesicoureteral Reflux
Midazolam Effect in Children Undergoing Voiding Cystourethrogram (VCUG)
The purpose of this research is to validate the common administration of oral midazolam to children prior to voiding cystourethrogram (VCUG) to see if this will significantly decrease children's anxiety and make the experience…
- Trial name
- NCT00894465
- Testing
- midazolam
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Vesicoureteral Reflux (VUR), Urinary Tract Infection
Polyacrylate Polyalcohol Copolymer for Vesicoureteral Reflux
Endoscopic correction of VUR has gained its popularity due to its less invasiveness, associated low morbidity and short hospital stay.
- Trial name
- NCT01926353
- Where
- Philippines
- Volunteers
- 25 people
- Sponsor
- St. Luke's Medical Center, Philippines
Vesicoureteral Reflux
Determination of Voiding Patterns of Children With Vesicoureteral Reflux
Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.
- Trial name
- NCT00186199
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Vesico-Ureteral Reflux, Filum Terminale Lipoma
Effects of Parental Holding on Pain Response in Young Children During Cystometry
Cystometry is essential for diagnosis and treatment plans by identifying the causes of lower urinary tract symptoms and objectively evaluating bladder functions in diseases such as neurogenic bladder, voiding dysfunction, and…
- Trial name
- NCT05864131
- Testing
- Lying, Holding
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Vesico-Ureteral Reflux
Clinical Applications of Contrast-Enhanced Ultrasonography in Pediatric Population - Intravesicle Administration
In children, specifically the intravesicle administration to study vesicoureteral reflux in children already catheterized and scheduled for voiding cystourethrogram (VCUG).
- Trial name
- NCT02986477
- Testing
- Contrast Ultrasound
- Sponsor
- Johns Hopkins University
Vesico-Ureteral Reflux
A Prospective Study Comparing the Success Rate of Injection of (DefluxR) Versus (VantrisR) for VUR in Children
Vesicoureteral reflux (VUR) is the most common urologic diagnosis in neonates estimated at 1% of newborns, and 30-45% of the children who present with urinary tract infection (1).
- Trial name
- NCT02271035
- Testing
- Deflux, Vantris
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Vesicoureteral Reflux
Prospective Pediatric Vesicoureteral Reflux Surgery Database
The purpose of this research is to provide a clearer understanding of quality and outcomes for three types of surgical procedures performed at Connecticut Children's for treatment of vesicoureteral reflux.
- Trial name
- NCT01373385
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Connecticut Children's Medical Center
Vesico-Ureteral Reflux
Endoscopic Injection of Dextranomer/Hyaluronic Acid Versus Ureteral Reimplantation In Treatment of Vesicoureteral Reflux
In this study, the investigators aim to compare the outcomes of Dextranomer/hyaluronic acid (Dexell®) and extravesical reimplantation (Lich- Gregoir) procedures for primary vesicoureteral reflux (VUR) grades III and IV in…
- Trial name
- NCT04798443
- Testing
- subureteral endoscopic Injection of Dextranomer/Hyaluronic acid (Dexell), open ureteral reimplantation (Lich-Gregoir)
- Volunteers
- 60 people
- Sponsor
- Elsayed Salih
VUR - Vesicoureteric Reflux
Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
The purpose of this study is to examine the applicability of contrast enhanced voiding ultrasonography in diagnosing vesicoureteral reflux (VUR) in pediatric patients compared to direct isotope cystography.
- Trial name
- NCT06138080
- Testing
- Contrast-enhanced voiding ultrasonography (CEVUS), Direct isotope cystography
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Vesicoureteral Reflux
Phase III Study of Chondrocyte Alginate Gel Suspension in Pediatric Patients With Vesicoureteral Reflux
OBJECTIVES: I. Determine the safety and efficacy of chondrocyte alginate gel suspension in pediatric patients with vesicoureteral reflux. II. Determine the long term efficacy of this treatment regimen in this patient population.
- Trial name
- NCT00004487
- Testing
- chondrocyte-alginate gel suspension
- Volunteers
- 60 people
- Sponsor
- FDA Office of Orphan Products Development
Vesico-Ureteral Reflux
CeVUS With Intravesical Administration of OPTISON TM (Trademark) in Children
In this clinical trial the investigators aim to evaluate the diagnostic feasibility and safety of ceVUS with the intravesical use of OPTISON for vesicoureteral reflux detection and urethral imaging in children.
- Trial name
- ceVUS (NCT02204917)
- Testing
- OPTISON
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kassa Darge
Vesicoureteral Reflux, Renal Hypodysplasia, Nonsyndromic, 1
Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract
The exact role of urinary tract infection in the appearance of chronic kidney disease is unclear. Children with congenital malformations of kidney and urinary tract have the higher risk of impairment of renal function.
- Conditions
- Vesicoureteral Reflux, Renal Hypodysplasia, Nonsyndromic, 1, Chronic Kidney Disease
- Trial name
- PREDICT (NCT02021006)
- Testing
- nitrofurantoin, No prophylaxis, Amoxicillin-Potassium Clavulanate Combination
- Where
- Italy
- Volunteers
- 292 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Vesicoureteral Reflux, Urinary Tract Infections
Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)
In this 2-year, multisite, randomized, placebo-controlled trial involving 607 children with vesicoureteral reflux that was diagnosed after a first or second febrile or symptomatic urinary tract infecton, we evaluated the efficacy…
- Trial name
- RIVUR (NCT00405704)
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- 19 sites in United States
- Volunteers
- 607 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Vesicoureteral Reflux
Study of Endoscopic Versus Open Surgery for Urinary Reflux
This study seeks to compare outcomes after anti-reflux surgery (ARS) for correction of low-grade vesicoureteral reflux (VUR). It is a randomized controlled open-label trial of conventional open anti-reflux technique versus…
- Trial name
- STRETCH (NCT00830479)
- Testing
- Anti-reflux surgery, Endoscopic injection
- Where
- United States
- Sponsor
- Boston Children's Hospital