Clinical trials: Vision Disorders
Primary Open Angle Glaucoma
Efficacy of Retinal Nerve Fiber Layer (RNFL) / Ganglion Cell Layer Thickness Ratio by RT-View Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma.
RT-View utilizes spectral domain technology to assess both RNFL and ganglion cell layer thickness. This study aims to correlate visual field defects in patients with glaucoma to both RNFL and ganglion cell layer thickness.
- Trial name
- NCT00773123
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Ocular Complications in AIDS Patients, Such as Fundus Opportunistic Infections, Microangiopathy, and Uveitis
Analysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation
Through a cross-sectional descriptive analysis of ophthalmic consultation of AIDS patients in the past 3 years, the basic characteristics of patients were described according to whether there was fundus change, and the clinical…
- Trial name
- NCT06250881
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhongnan Hospital
Healthy Volunteers Eligible for Study; Drug Being Developed for Allergic Conjunctivitis
Safety Study of Ophthalmic Solution in Healthy, Normal Volunteers
The purpose of this study is to evaluate the safety of R89674 0.25% ophthalmic solution in healthy normal volunteers
- Trial name
- NCT00223951
- Testing
- R89674 (generic name not yet established)
- Where
- 6 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Convergence Insufficiency
Efficacy Of Pencil Pushup Exercise Vs Base Out Exercising Prism's In Patient With Convergence Insufficiency
Convergence insufficiency (CI) is a prevalent binocular vision disorder that leads to symptoms such as eye strain, headaches, and blurred vision during near work.
- Trial name
- NCT06913829
- Testing
- base-out exercising prisms, pencil pushup exercises
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Superior University
Onchocerciasis
Ocular Changes After Ivermectin - (DOLF IVM/Oncho)
The DOLF Ocular Changes after Ivermectin study will investigate the kinetics of O. volvulus microfilaria (Mf) in the eye following treatment with ivermectin.
- Trial name
- NCT03517462
- Testing
- Ivermectin 3Mg Tab
- Where
- Ghana
- Volunteers
- 231 people
- Sponsor
- Washington University School of Medicine
Open Angle Glaucoma and Cataract
RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.
Post-operative cystoid macular oedema (CMO) is a common complication causing visual loss following routine cataract surgery. This complication is more prevalent in eyes with excessive inflammation as they heal from surgery.
- Trial name
- CMO (NCT03292796)
- Testing
- Prostaglandins
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Julie Dawson
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University
Retinopathy of Prematurity (ROP), Prematurity Complications
Retinopathy of Prematurity - Visual Function and Retinal Structure
Children born prematurely may develop a characteristic retinal disease named retinopathy of prematurity (ROP). This disease could lead to retinal detachment and blindness.
- Conditions
- Retinopathy of Prematurity (ROP), Prematurity Complications, Cerebral Visual Impairment, Visual Field Defect
- Trial name
- NCT07427719
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Amblyopia
Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia
To determine whether the success rate with drug treatment (atropine) of amblyopia due to strabismus or anisometropia in patients less than 7 years old is equivalent to the success rate with occlusion (patching) therapy To develop…
- Trial name
- NCT00000170
- Testing
- Atropine, Eye Patch
- Where
- United States
- Volunteers
- 419 people
- Sponsor
- Jaeb Center for Health Research
Visual Impairment
Cell Phone Application for Vision Assessment
The purpose of this study is to evaluate how visual acuity assessed with Peek Acuity (a cell phone application to check visual acuity) among preschool and school-aged children 3 to less than18 years of age (1) compares to the…
- Trial name
- NCT03212222
- Testing
- Peek Acuity, Standard Visual Screening
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Duke University
Glaucoma, Ocular Hypertension
Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertension
The purpose of this study is to evaluate the safety and efficacy of BETOPTIC S and Timolol Gel-forming solution in pediatric patients. Patients will dose with study drug at 8 am and 8 pm daily for twelve weeks.
- Trial name
- NCT00061542
- Testing
- BETOPTIC S (betaxolol HCl), Timolol Gel-forming Solution (TGFS)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Corneal Diseases
Dynamic Light Scattering and Keratoscopy for Corneal Examination
This pilot study will examine the usefulness of a new instrument called the Dynamic Light Scattering (DLS) device for documenting and monitoring changes in the cornea, the front part of the eye where contact lenses are placed.
- Trial name
- NCT00050466
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Glaucoma, Open-Angle, Ocular Hypertension
Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
This is an observational study of Lumigan® 0.01% (bimatoprost) treatment in clinical practice for patients with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).
- Trial name
- NCT01628588
- Testing
- bimatoprost 0.01%
- Where
- Netherlands
- Volunteers
- 854 people
- Sponsor
- Allergan
Glaucoma
AADI Glaucoma Shunt - a Quality Control Study
To prospectively investigate the effect and safety of implantation of the AADI glaucoma tube in eyes with medically intractable glaucoma in the period 2019 to 2020, at the Department of Ophthalmology, Odense University Hospital.
- Trial name
- NCT03850054
- Testing
- AADI glaucoma shunt
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- Odense University Hospital
Myopia
Investigation of the Regulation of Retinal and Choroidal Blood Vessels in Various AL Based on WF SS-OCTA Detection With Changes in Body Position
This prospective observational study aims to understand the effects of different subaxial body positions on choroidal and retinal blood vessel density.
- Trial name
- NCT06587776
- Volunteers
- 60 people
- Sponsor
- Science and Technology Department of Sichuan Province
Myopia
Binocular Peripheral Myopic Defocus Using a Clinical Prototype Device
Kubota Vision Inc. has developed a spectacle-like prototype device which is designed to be used as a light-based therapy to reduce myopia progression.
- Trial name
- NCT05425108
- Testing
- Binocular CP1
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kubota Vision Inc.
Vision Disorders, Vision, Low
Viewing Strategy Training in Children With (Cerebral) Visual Impairment
Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies.
- Trial name
- NCT05600140
- Testing
- Viewing strategy training
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Dutch Visio
Mitochondrial Diseases, Kearns-Sayre Syndrome
Global Registry and Natural History Study for Mitochondrial Disorders
The main goal of the project is provision of a global registry for mitochondrial disorders to harmonize previous national registries, enable world-wide participation and facilitate natural history studies, definition of outcome…
- Conditions
- Mitochondrial Diseases, Kearns-Sayre Syndrome, MIDD, SANDO
- Trial name
- GENOMIT (NCT05554835)
- Where
- 34 sites in Austria, Germany and 1 more
- Volunteers
- 6,000 people
- Sponsor
- LMU Klinikum
One Eye Blindness, Blind Left Eye
Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision
The investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye).
- Conditions
- One Eye Blindness, Blind Left Eye, Blind Right Eye
- Trial name
- NCT06024668
- Testing
- Multiplexing Prism
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary