Clinical trials: Vision Loss
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Visual Rehabilitation, Oddball Design
In-person and Telehealth Visual Rehabilitation for Children With Low Vision
Restorative visual rehabilitation is frequently used to enhance the visual development and function of children with low vision.
- Conditions
- Visual Rehabilitation, Oddball Design, Cerebral Visual Impairment, Passive Visual Stimulation
- Trial name
- NCT06701617
- Testing
- restorative visual rehabitation
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Demographic Profiles, Impairment Certificates
Patients Seeking a Visual Impairment Certificate
This study investigates the prevalence, causes, and demographic characteristics of patients seeking visual impairment certificates at Assiut Ophthalmology Hospital.
- Conditions
- Demographic Profiles, Impairment Certificates, Visual Impairment
- Trial name
- NCT06900855
- Volunteers
- 383 people
- Sponsor
- Assiut University
Retinitis Pigmentosa, Usher Syndromes
Prospective Open Clinical and Genetic Study of Patients With Retinitis Pigmentosa
This study is aimed to characterize Russian population of Retinitis Pigmentosa
- Trial name
- RU-RP (NCT03901391)
- Testing
- Whole Exome Sequencing
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Sensor Technology for Deafblind
Retinitis Pigmentosa, Cone Dystrophy
Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.
Patients with retina dystrophies (retinitis pigmentosa, cone>rods dystrophies, Usher and syndromic) will be correlated with genotype and validate inheritance mode by segregation analysis.
- Conditions
- Retinitis Pigmentosa, Cone Dystrophy, Usher Syndromes, Retina; Dystrophy
- Trial name
- NCT03990727
- Testing
- Retina Analysis-mosaic, Autofluorescence, OCT- 1 micra
- Where
- Mexico
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- MejoraVisionMD
Vision Disability
Assessment of an Augmented Reality Low Visual Aid in Children and Young People With Visual Impairment
Approximately 24,500 children and young people (CYP) in England have a visual impairment (VI). VI refers to a loss of vision that cannot be corrected with glasses or contact lenses. Low vision aids (e.g.
- Trial name
- NCT05201482
- Testing
- SightPlus
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Visual Impairment, Refractive Error
Frequency of Visual Impairment Among School Children and Effectiveness of mHealth Referral Reminder on Uptake of Referral Services
This study tested whether mobile health (mHealth) tools can affect referral uptake among schoolchildren with vision problems.Visual impairment in children often goes untreated in low- and middle-income countries, even when…
- Trial name
- NCT06616051
- Testing
- Multicomponent SMS reminder
- Where
- Pakistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Syed Fawad Mashhadi
Stargardt Disease, Stargardt Macular Dystrophy
A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions
Macular dystrophies are a group of inherited eye conditions that affect the macula. The macula is in the center of the retina, the light sensitive part at the back of the eye.
- Conditions
- Stargardt Disease, Stargardt Macular Dystrophy, Stargardt-like Macular Dystrophy
- Trial name
- DEVOTE (NCT07734064)
- Testing
- ASP2020
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Astellas Institute for Regenerative Medicine
Choroidal Neovascularization (CNV)
Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.
This study was conducted to evaluate the efficacy and safety of 0.5 mg ranibizumab in adult and adolescent patients with visual impairment due to choridal neovascularization (CNV).
- Trial name
- NCT01840410
- Testing
- Ranibizumab
- Where
- 59 sites in Australia, Canada and 19 more
- Volunteers
- 183 people
- Sponsor
- Novartis Pharmaceuticals
Autism Spectrum Disorder, Visual Rehabilitation
Visual Rehabilitation in Children With Autism Spectrum Disorder and Visual Disorders
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication.
- Conditions
- Autism Spectrum Disorder, Visual Rehabilitation, Vision, Social Communication
- Trial name
- NCT07644468
- Testing
- Visual Rehabilitation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- National Taiwan University Hospital
Cortical Visual Impairment
Remote Access: Cortical Visual Impairment
This study aims to compare the efficacy of an in-home telehealth-based intervention to standard care for children with cortical visual impairment and their caregivers and to assess the feasibility and acceptability of an in-home…
- Trial name
- NCT03957980
- Testing
- Occupational therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Visual Pathway Diseases; Neuroimaging
Brain Lesions in Relation to Motor Profiles of Children With Cerebral Visual Impairment.
The overall goal of this research proposal is the early prediction of the emergence of CVI and its characteristics on the basis of neuroimaging data. The different steps that will be taken to achieve this goal will be: 1.
- Trial name
- NCT02480452
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myopia, Visual Fatigue
Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Background: Tea is a universal beverage and one of the most popular drinks around the world. Some cell and animal experiments have pointed out that drinking tea may be related to hypotension, body composition and vision problems…
- Conditions
- Myopia, Visual Fatigue, Blood Pressure, Body Composition
- Trial name
- NCT06570226
- Testing
- hibiscus tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Age-related Macular Degeneration
Visual Remapping to Aid Reading With Field Loss
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
- Trial name
- NCT03848663
- Testing
- Traditional Remapping, Personalized Remapping
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Wolfram Syndrome, Diabetes Mellitus
A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome
Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, diabetes insipidus, optic nerve atrophy, hearing loss, and neurodegeneration.
- Conditions
- Wolfram Syndrome, Diabetes Mellitus, Optic Nerve Atrophy, Ataxia
- Trial name
- NCT02829268
- Testing
- dantrolene sodium
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Healthy
Effectiveness of the Serious Game 'Broodles' for Siblings of Children With Visual Impairment and/or Intellectual Disability
The support for siblings of children with disabilities is scarce and fragmented, even though studies have shown that these siblings can benefit from support.
- Trial name
- NCT05376007
- Testing
- Serious game 'Broodles'
- Where
- Netherlands
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Headache, Urinary Incontinence
Pediatric Patient Experience on a Diagnostic Path
The trial will determine the impact of an information- and education-focused interventions on the anxiety levels, and patients' experiences as well as satisfaction of patients aged 10-14 and their caregivers during the MR…
- Conditions
- Headache, Urinary Incontinence, Growth Deficiency, Visual Impairment
- Trial name
- NCT05199363
- Testing
- Information leaflet, Educational movie, Demonstration
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Children's Memorial Health Institute, Poland