Clinical trials: Visual Disorder
Demyelinating Disease
Pharmacological Recruitment of Endogenous Neural Precursors to Promote Pediatric White Matter Repair: Establishing Correlations Between Visual Outcomes, Saccadic Function and MEG Oscillations in Children With Demyelinating Disorders in Comparison to Healthy Control Children
The neural circuits in our brains require a layer of insulation in order to transmit signals in a rapid and efficient fashion. This insulation is called White Matter and is comprised of a specific type of brain cell called an…
- Trial name
- NCT03010826
- Where
- 2 sites in Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder
Sand Play vs. Cuff Training: Visual-Motor Skills in Autism
This study compares Image-Sand Play Therapy and Tabletop Training with Weighted Cuffs for improving Visual-Motor Integration (VMI) in children with autism.
- Trial name
- NCT06943248
- Testing
- Image-Sand Play Therapy, Table Top Training Program with Weighted Cuff
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Cerebral Palsy, Visual Impairment
Turkish Validity and Reliability of the Visual Function Classification System (VFCS)
Cerebral Palsy (CP) is the most common childhood disorder that occurs with a lesion in the developing infant brain, seen in 2-3/1000 live births.
- Conditions
- Cerebral Palsy, Visual Impairment, Visual Disorder, Cerebral Visual Impairment
- Trial name
- NCT05102955
- Testing
- Observational questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Diabetes Mellitus, Type 1, Monogenic Diabetes
Monogenic Diabetes Misdiagnosed as Type 1
The study has two aims: 1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection. 2.
- Conditions
- Diabetes Mellitus, Type 1, Monogenic Diabetes, Neonatal Diabetes, Maturity-onset Diabetes in the Young (MODY)
- Trial name
- ADDAM (NCT03988764)
- Testing
- None AHT
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Amblyopia, Healthy
Amblyopia and Stereoptic Games for Vision
Amblyopia is the most common developmental vision disorder in children, caused by abnormal visual experience in early life, especially a difference in refraction between the eyes, a misalignment of the eye axes, a combination of…
- Trial name
- AMBER (NCT05114252)
- Testing
- Vivid Vision Home, Refractive error correction
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pawel Matusz, PhD
Loss of Visual Contrast Sensitivity, Near Vision
Visual Performance Following Implantation of Presbyopia Correcting IOLs
The purpose of the current study was to compare the visual performance after bilateral implantation of the Panoptix IOL , or the AT LISA IOL or Tecnis Symfony IOL .
- Conditions
- Loss of Visual Contrast Sensitivity, Near Vision, Visual Impairment
- Trial name
- NCT04907955
- Testing
- phacoemulsification with implantation of presbyopia correcting IOL
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Dar Al Shifa Hospital
Retinitis Pigmentosa
The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis Pigmentosa
The aim of this study is to determine whether 9-cis-beta Caroten rich D. Brdawiil extract is effective in the treatment of retinitis pigmentosa in adolescent patients.
- Trial name
- NCT02018692
- Testing
- Alga Dunaliella Bardawil powder
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Low Grade Glioma, Neurofibromatosis Type 1
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in…
- Conditions
- Low Grade Glioma, Neurofibromatosis Type 1, Visual Pathway Glioma
- Trial name
- NCT03871257
- Testing
- Carboplatin, Magnetic Resonance Imaging, Quality-of-Life Assessment
- Where
- 132 sites in United States, Canada and 1 more
- Volunteers
- 165 people
- Sponsor
- National Cancer Institute (NCI)
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Amblyopia
Evaluation of Amblyopia Protocols Using a Dichoptic Gabor Videogame Program
Interest in developing alternative methods for the treatment of amblyopia (lazy eye) has long been a topic of interest among clinicians and researchers.
- Trial name
- NCT06150391
- Testing
- Visionary: computer exercises using dichoptic Gabor Patches and band-filtered noise masks, Patching
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital de Merida
Bilateral Refractive Amblyopia
Bilateral Refractive Amblyopia Treatment Study
The purpose of this study will be to: Determine the amount of visual acuity improvement with treatment of presumed bilateral refractive amblyopia Determine the time course of visual acuity improvement with treatment
- Trial name
- ATS7 (NCT00305955)
- Testing
- Spectacles
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Jaeb Center for Health Research
Anisometropic Amblyopia, Strabismic Amblyopia
3D Movie Viewing vs Occlusion for Treating Amblyopia in Children
Amblyopia is a common childhood visual disorder that affects vision in one eye and can also impair depth perception (stereopsis).
- Trial name
- VISTA3D (NCT07563946)
- Testing
- 3D Movie Viewing, Occlusion Therapy
- Volunteers
- 56 people
- Sponsor
- Universitat Politècnica de Catalunya
Neurofibromatosis Type 1 (NF1), NF2-related Schwannomatosis
How Can the Experience of Hospital Outpatient Departments be Improved?
This project aims to improve outpatient departments by working with patients and staff to make these spaces more inclusive for people with sensory challenges (it focuses on people with nerve tumour conditions as they are more…
- Trial name
- NCT07818213
- Testing
- Qualitative data collection activities
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Amblyopia
Efficacy of Visual Screening in Ontario
Amblyopia (lazy eye), is the leading treatable cause of vision loss in childhood. Uncorrected refractive errors (ie farsightedness) can lead to difficulties in school.
- Trial name
- NCT02458846
- Testing
- Crowded HOTV Acuity Test, Preschool Randot Stereoacuity Test, Plusoptix Autorefractor
- Where
- Canada
- Volunteers
- 2,597 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Amblyopia, Strabismus
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits.
- Trial name
- NCT04310241
- Testing
- Patching therapy, Glasses
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cognitive Performance, Sleep Quality
The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians
This study aimed to examine the impact of caffeinated chewing gum on the cognitive performance of night-shift emergency physicians in a partially sleep-deprived state.
- Trial name
- NCT06693505
- Testing
- caffeinated chewing gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Renal Fanconi Syndrome, Photophobia
Biomarker for Cystinosis Disease: BioCystinosis (BioCystinosis)
Development of a new mass spectrometry-based biomarker for the early and sensitive diagnosis of Cystinosis disease from the blood
- Conditions
- Renal Fanconi Syndrome, Photophobia, Hypophosphatemia
- Trial name
- BioCystinosis (NCT02837523)
- Where
- 4 sites in Germany, India and 1 more
- Sponsor
- CENTOGENE GmbH Rostock
Ophthalmic Disorders
Co-designing and Evaluating a Real-world Implementation Model for Remote Consultation with Vision Self-testing.
This study aims to involve the public, patients and National Health Service (NHS) staff in co-designing a scalable, inclusive and sustainable implementation model for ophthalmic remote consultation with vision self-testing (the…
- Trial name
- ReVise (NCT05941182)
- Testing
- online questionnaires
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Retinal Detachment, Vitrectomy
Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy
To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up.
- Trial name
- NCT03902795
- Testing
- Microperimetry, M-charts
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin