Clinical trials: Vitrectomy
Proliferative Diabetic Retinopathy
Surgical Outcomes for Proliferative Diabetic Retinopathy by Preoperative Glycemic Control and Renal Function
The surgical outcomes of 25-gauge vitrectomy for proliferative diabetic retinopathy has been evaluated by preoperative glycemic control and renal function
- Trial name
- NCT03522311
- Testing
- Vitrectomy
- Volunteers
- 251 people
- Sponsor
- Kyorin University
Glaucoma Secondary
Treatment of Malignant Glaucoma by Anterior Vitrectomy From Two Different Approaches
To compare the surgical outcomes of treating phacoemulsification with intraocular lens implantation combined with goniosynechialysis (Phaco-IOL-GSL) associated malignant glaucoma (MG), using different incision sites in anterior…
- Trial name
- NCT04172857
- Testing
- anterior vitrectomy combined with hyaloidotomy, zonulectomy and iridectomy
- Volunteers
- 9 people
- Sponsor
- Wenzhou Medical University
Retinal Edema
Suprachoroidal Injection of Triamcinolone Acetonide in Resistant Diabetic Macular Edema, CRVO, Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema Following Pars Plana Vitrectomy
Prospective interventional study on 60 eyes of resistant diabetic macular edema and central retinal vein occlusion that will receive suprachoroidal injection of Triamcinolone Acetonide (SCTA).
- Trial name
- Resistant (NCT04690608)
- Testing
- Triamcinolone Acetonide 40Mg/Ml Inj,Susp_#1
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Rhegmatogenous Retinal Detachment
Healaflow Patch for the Treatment of Rhegmatogenous Retinal Detachment
To report the surgical results of primary rhegmatogenous retinal detachment (RRD) repaired by 27G pars plana vitrectomy (PPV) combined with Healaflow patch and air tamponade, and do not need prone position postoperation.
- Trial name
- NCT03542162
- Testing
- Healaflow
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Dislocated Lens, Pars Plana Vitrectomy
Effectiveness and Safety of 25-Gauge Needle-Assisted Phacoemulsification of Dislocated Intravitreal Lens Nucleus
The goal of this observational study is to learn about the effects of 25-gauge (G) needle-assisted phacoemulsification to remove dislocated intravitreal lens nuclei.
- Conditions
- Dislocated Lens, Pars Plana Vitrectomy, Phacoemulsification, Needle
- Trial name
- NCT06709378
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Changzhou No.2 People's Hospital
Proliferative Diabetic Retinopathy
OCT and OCT-A Afer Diabetic Vitrectomy in PDR
Detection of any structural or vascular changes at the macula after Pars Plana Vitrectomy ( PPV ) in cases with complicated proliferative diabetic retinopathy ( PDR )
- Trial name
- NCT05938491
- Testing
- OCT and OCT-A
- Volunteers
- 30 people
- Sponsor
- Assiut University
Proliferative Diabetic Retinopathy
Efficacy of PreOperative Bevacizumab for Diabetic Eye Disease
Reports of the use of intravitreal bevacizumab (Avastin, Genentech) for the reduction of neovascularization in proliferative diabetic retinopathy have demonstrated significant regression in the number of new vessels.
- Trial name
- NCT01041690
- Testing
- Bevacizumab
- Where
- Egypt
- Volunteers
- 19 people
- Sponsor
- Cairo University
Macular Hole, Retinal Detachment
Effect of Topical Aqueous Suppressants on Intraocular Gas Duration Following Pars Plana Vitrectomy
The purpose of this study is to see if glaucoma eye drops (dorzolamide-timolol) have any effect on the duration of an intraocular gas bubble following pars plana vitrectomy.
- Trial name
- NCT01257698
- Testing
- Dorzolamide 2%-timolol 0.5% topical eyedrops
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mid Atlantic Retina
Epiretinal Membrane
Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal…
- Trial name
- NCT01771939
- Testing
- 25-G vitrectomy and phacoemulsification, phacoemulsification (cataract surgery)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Congenital Cataract
Inflammatory Cytokines in Congenital Cataract After Lensectomy and Anterior Vitrectomy
In this prospective study , a cohort of 58 eyes with congenital cataract from Wenzhou medical university was erolled.33 eyes with congenital cataract was after lensectomy and anterior vitrectomy as post-surger group, 26 eyes…
- Trial name
- NCT04120818
- Testing
- secondary IOL implantation, primary IOL implantation
- Where
- 2 sites in China
- Volunteers
- 59 people
- Sponsor
- yin ying zhao
Epiretinal Membrane, Macular Edema
Dexamethasone Intravitreal Implant After Vitrectomy For Epiretinal Membrane
The purpose of this study is to evaluate the effect of dexamethasone intravitreal implant (Ozurdex) in combination with pars plana vitrectomy and membrane peeling for idiopathic epiretinal membrane (ERM).
- Trial name
- OZURDEX2 (NCT01410201)
- Testing
- Dexamethasone Intravitreal Implant
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Barnes Retina Institute
MicroRNA Expression Profile in Human Vitreous of Various Vitreoretinal Diseases
MicroRNA Expression Profile in Human Vitreous of Patients With Various Vitreoretinal Diseases Requiring Vitrectomy
MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear. Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of patients…
- Trial name
- NCT01674023
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Kyorin University
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Macular Detachment, Macular Retinoschisis
Macular Detachment Associated With Intrachoroidal Cavitation
Evaluation of clinical characteristics and surgical outcome for macular detachment associated with peripapillary intrachoroidal cavitation with or without pathologic myopia.
- Conditions
- Macular Detachment, Macular Retinoschisis, Intrachoroidal Cavitation
- Trial name
- NCT01959724
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Kyorin University
Pediatric Rhegmatogenous Retinal Detachment
Outcomes of Vitrectomy in Pediatric Retinal Detachment With Proliferative Vitreoretinopathy
The aim of this study is to report outcomes of pars plana vitrectomy (PPV) in pediatric retinal detachment (RD) accompanied with proliferative vitreoretinopathy (PVR) as well as complications and factors influencing the final…
- Trial name
- NCT03208205
- Testing
- vitrectomy
- Where
- Poland
- Volunteers
- 14 people
- Sponsor
- Medical University of Lublin
Retinopathy of Prematurity Both Eyes, Retinal Disease
Safety and Efficacy of 18 mm Short Vitrectomy Probe for Pediatric Vitreoretinal Surgeries
This study aims to study the safety and efficacy of using an 18 mm short vitrectomy probe for pediatric vitreoretinal surgeries and to investigate the surgeon's comfort and reliability of using the shorter probe.
- Conditions
- Retinopathy of Prematurity Both Eyes, Retinal Disease, Persistent Fetal Vasculature, Coats Disease
- Trial name
- NCT06520410
- Testing
- Pars plana vitrectomy with a 18 mm short vitrector
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
PDR
A Single-Center Trial of Intravitreous Injections of Macugen (Pegaptanib Sodium) Given at Least 7 Days Before Vitrectomy Secondary To Tractional Retinal Detachment in Proliferative Diabetic Retinopathy
Primary objective of this trial will be to evaluate the safety and efficacy of intravitreal injections of Macugen (pegaptanib sodium) when given at least 7-14 days prior to vitrectomy in subjects with tractional retinal…
- Trial name
- NCT01487070
- Testing
- Macugen (Pegaptanib Sodium)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Retina Institute of Hawaii
Retinal Detachment
Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment.
The investigators compared the incidence of trimming-induced retinal breaks, retinal redetachment rate, and final LogMAR BCVA; between scleral self-indentation and non-indentation during chandelier-assisted peripheral vitrectomy…
- Trial name
- NCT03218371
- Testing
- chandelier-assisted peripheral vitrectomy under air
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Dar El Oyoun Hospital
Corneal Epithelial Defect
The Role of Umbilical Cord Serum Therapy on Improvement of Corneal Epithelial Defect Following Diabetic Vitrectomy
80 diabetic patients underwent vitrectomy and had no history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency will be randomized into two groups (double blind)to evaluate the role of umbilical…
- Trial name
- NCT01168375
- Testing
- conventional therapy plus umbilical cord serum eye drop, conventional therapy
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Rhegmatogenous Retinal Detachment
Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment
The purpose of this research study is to compare the outcomes of pneumatic retinopexy with the outcomes of vitrectomy (with or without scleral buckle) for the management of retinal detachment, in terms of anatomical success…
- Trial name
- NCT01639209
- Testing
- Vitrectomy, Pneumatic retinopexy
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Unity Health Toronto