Clinical trials: Vulnerable Populations
Treatment Adherence
Pilot Study of a Transition Intervention for ALWH
The investigators will conduct a pilot study of a community-based intervention designed to improve outcomes among adolescents living with HIV (ALWH) transitioning to adult HIV care in Lima, Peru.
- Trial name
- PASEO (NCT05022706)
- Testing
- Community-based accompaniment and home visits, Directly Observed Therapy, Monthly Peer Support Groups
- Where
- 3 sites in Peru
- Volunteers
- 30 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Fracture, Influenza Vaccination
Influenza Vaccination Against Infectious Complications and Mortality in Older Adults With Fractures: a Large-scale Retrospective Cohort Study
Background: Both influenza and bone fractures are significant contributors to morbidity and mortality among older adults. This study evaluated the associations between influenza vaccination (IV) and adverse outcomes following…
- Trial name
- NCT07231016
- Where
- Taiwan
- Volunteers
- 561,566 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Covid19
Community Network-driven COVID-19 Testing and Vaccination of Vulnerable Populations in the Central US
This C3 project, Community network-driven COVID-19 testing of vulnerable populations in the Central US, will implement and evaluate a COVID-19 testing and vaccination approach that combines an evidence-based Social Network…
- Trial name
- C3 (NCT04743908)
- Testing
- Social Network Strategy + COVID-19 messaging
- Where
- United States
- Volunteers
- 1,328 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Internet-Based Intervention
Evaluation of the First Pathways Game on Parent-child Interactions and Development for Vulnerable Children
Children's brains develop quickly in the first three years of life and are particularly sensitive to their environment. Adverse experiences, such as exposure to abuse and neglect, can increase children's risk for behavioral…
- Trial name
- NCT04902404
- Testing
- First Pathways Game
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 2
A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston
To improve diabetes self-management outcomes, patients with type 2 diabetes (n=150 - aged 13-84) recruited from St. Vincent Clinic (SVC) and Teen Health Center Inc., Clinics will be randomized using block randomization to receive…
- Trial name
- NCT05097534
- Testing
- iDSMES, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Health Behavior
Ecology of Medical Care - Utilisation of Health Care in Austria
BACKGROUND: A proper understanding of the attitudes towards its own health status and concise estimates concerning the health seeking behavior of the different subgroups of a population are highly desirable.
- Trial name
- ECOHCARE (NCT01261845)
- Where
- Austria
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Breastfeeding, Breastfeeding, Exclusive
Parkdale Infant Nutrition Security Targeted Evaluation Project: Infant Feeding
In Toronto Ontario, the Parkdale Community Health Centre operates a community outreach program entitled Parkdale Parents' Primary Prevention Project (5P's).
- Conditions
- Breastfeeding, Breastfeeding, Exclusive, Infant Nutrition, Vulnerable Population
- Trial name
- PINSTEP-3 (NCT03400605)
- Testing
- Infant feeding questionnaire
- Where
- Canada
- Volunteers
- 203 people
- Sponsor
- University of Toronto
HIV, Hepatitis C
Effects of Motivational Interviewing on Risky Injecting Practices Among Injecting Drug Users (IDUs)
The purpose of this study is to evaluate the effects of a brief motivational intervention in reducing risky injection practices among injecting drug users (IDUs).
- Trial name
- NCT00794391
- Testing
- Motivational interviewing, Educational intervention
- Where
- Canada
- Volunteers
- 219 people
- Sponsor
- Université de Sherbrooke
Cancer Prevention
Getting Ahead for Cancer Control
A new, practical program, entitled Getting Ahead in a Just-Gettin'-By World, provides a novel approach to addressing this previously intractable problem.
- Trial name
- NCT03247634
- Testing
- Getting Ahead in a Just-Gettin'-By World
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Cardiovascular Health, Food Insecurity
Educational Strategy on a Vulnerable Population to Improve Cardiovascular Health and Food Insecurity
The purpose of this study is to demonstrate that an educational program on a healthy lifestyle which increases health literacy could improve long-term health and mitigate food insecurity.
- Conditions
- Cardiovascular Health, Food Insecurity, Healthy Lifestyle, Vulnerable Population
- Trial name
- E-DUCASS (NCT05379842)
- Testing
- Education on a healthy lifestyle and health literacy
- Where
- Spain
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Obesity & Overweight, Vulnerable Families
Evaluation of a Multicomponent Early Intervention for Childhood Obesity Prevention in Vulnerable Families
Childhood obesity is a public health concern. Evidence-based, multicomponent, parenting interventions targeting early childhood and adapted to families' socioeconomic context are needed to prevent childhood obesity.
- Conditions
- Obesity & Overweight, Vulnerable Families, Children, Families With Infants
- Trial name
- Bambú (NCT07529704)
- Testing
- Bambú program
- Where
- 4 sites in Spain
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Helena Vall Roqué
Child Development, Developmental Disabilities
Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening
The purpose of this research study is to test the effectiveness of telephone-based early childhood developmental screening and care coordination, compared to usual care in a primary care pediatrics clinic.
- Conditions
- Child Development, Developmental Disabilities, Ambulatory Care, Screening
- Trial name
- NCT02495025
- Testing
- Telephone-based developmental screening and care coordination
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Breastfeeding, Breast Pumping
Parkdale Infant Nutrition Security Targeted Evaluation Project: Focus Groups & Interviews
In Toronto Ontario, the Parkdale Community Health Centre operates a community outreach program entitled Parkdale Parents' Primary Prevention Project (5P's).
- Conditions
- Breastfeeding, Breast Pumping, Infant Nutrition, Vulnerable Population
- Trial name
- PINSTEP-2 (NCT03305406)
- Testing
- Focus groups, Interviews
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prenatal Community Program, Vulnerable Population
Parkdale Infant Nutrition Security Targeted Evaluation Project: Chart Review
In Toronto Ontario, the Parkdale Community Health Centre operates a community outreach program entitled Parkdale Parents' Primary Prevention Project (5P's).
- Conditions
- Prenatal Community Program, Vulnerable Population, Postnatal Community Program
- Trial name
- PINSTEP-1 (NCT03372408)
- Testing
- Chart review
- Where
- Canada
- Volunteers
- 338 people
- Sponsor
- University of Toronto
Volatile Organic Compounds, Radiography
Tuberculosis Screening in Paraguayan Prisons
Two diagnostic tools for TB screening in high risk groups need additional assessment: the AeoNose™, an 'electronic nose device' for breath sampling, and digital chest X-ray (CXR) with computer aided detection with CAD4TB®…
- Trial name
- Prinose (NCT04407325)
- Testing
- electronic nose device, dig chest Xray with automated readings
- Where
- 2 sites in Paraguay
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Food Insecurity, Vulnerable Populations
Enrollment in and Utilization of the Flex Nutrition Program
The goal of this clinical trial is to learn about the impact of proactive outreach on enrollment into and utilization of the Flexible Services Nutrition Program.
- Conditions
- Food Insecurity, Vulnerable Populations, Nutrition, Healthy
- Trial name
- NCT05972421
- Testing
- High Intensity Proactive Outreach, Low Intensity Proactive Outreach
- Volunteers
- 255 people
- Sponsor
- Massachusetts General Hospital
Pediatric HIV Infection
Evaluating an HIV Risk Screening Tool for Orphans and Vulnerable Children in Tanzania
The goal of the research was to evaluate the performance of items within the Kizazi Kipya (K2) Orphan and Vulnerable Children (OVC) HIV risk screening tool in identifying HIV-positive children, to optimize an HIV screening tool…
- Trial name
- NCT04517760
- Where
- Tanzania
- Volunteers
- 21,080 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Food Insecurity
Nurturing Outreach for Understanding and Reducing Inpatient Security of Health
Food insecurity is the lack of consistent access to the food needed for a healthy life. Food insecurity among families whose child has been hospitalized is a critical problem affecting a large, vulnerable population.
- Trial name
- NOURISH (NCT07010289)
- Testing
- Prepared Meals, Grocery Gift Cards, Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Fig. Impetuous
Based on the Data from the Zhejiang Emergency Center, Explore the Independent and Interactive Effects of the Association Between Meteorological Factors and Air Pollution and the Number of Emergency Personnel, Identify the Relevant Vulnerable Population Characteristics, Sensitive Disease Types
Based on the health data from Zhejiang Emergency Command Center, combined with meteorological, air pollution, land use and socio-economic data of Zhejiang Province, distributional lag nonlinear models, grouped weighted quantile…
- Trial name
- NCT06798987
- Testing
- Meteorological conditions and air pollution
- Where
- China
- Volunteers
- 1,500,000 people
- Sponsor
- Li hengjie
Perinatal Outcomes, Social Determinants of Health (SDOH)
Rhode Island Community-based Maternal Support Services
The purpose of this project is to improve perinatal health outcomes in Rhode Island by bringing together the hospital, community health workers (CHWs), doulas, and community-based organizations to build a service delivery model…
- Conditions
- Perinatal Outcomes, Social Determinants of Health (SDOH), Health Disparity, Minority and Vulnerable Populations, Pregnancy
- Trial name
- RICOMSS (NCT07446374)
- Testing
- Perinatal health screening, Support services
- Where
- 7 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Women and Infants Hospital of Rhode Island