Clinical trials: asthma
Asthma
A Patient-Centered Asthma Management Communication Intervention for Rural Latino Children
The purpose of this research is to develop and evaluate an mHealth communication intervention designed to improve asthma medication adherence amongst rural Latino children in South Carolina.
- Trial name
- NCT04633018
- Testing
- AsthmaMD mobile application, Usual care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Asthma
Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy
Asthma is a growing problem, especially in children. It causes frequent wheezing, shortness of breath, chest tightness, and cough. A cold that is caused by a virus (viral cold) can sometimes make asthma symptoms worse.
- Trial name
- MUPPITS-1 (NCT02502890)
- Where
- 9 sites in United States
- Volunteers
- 208 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Prospective Study of Dietary Factors, BMI, and Risk of Asthma in Children
Asthma is a common illness among children in the United States. While there are many known causes of asthma, including tobacco smoke, pollen, dust, or other allergens, the exact cause of asthma in some individuals remains…
- Trial name
- NCT00454415
- Where
- United States
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma
Clinical Relevance of Small Airways Disease in Severe Asthma Patients Treated With Anti-InterLeukin-5 Therapy
The aim of this research is to investigate the extent and clinical relevance of small airways disease in severe eosinophilic asthma patients treated with anti-IL5/5R therapy.
- Trial name
- SAIL (NCT05706597)
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Frisius Medisch Centrum
Asthma, Bronchial Hyperresponsiveness
The Effect of HFA - Beclomethasone Dipropionate Qvar on Bronchial Hyperreactivity in Preschool Children
Respiratory diseases including Asthma are high prevalent among preschool children. Specific treatment, nowadays, include steroid inhalers and anti leukotrienes.
- Trial name
- NCT01006655
- Testing
- Beclomethasone dipropionate HFA
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Rambam Health Care Campus
Asthma in Offspring
Acid-suppressing Drugs Pregnancy Asthma Offspring Study
The purpose of this study is 1. To estimate the association between prenatal exposure to proton pump inhibitors (PPIs) and the risk of asthma during childhood. 2.
- Trial name
- NCT01787435
- Testing
- Risk of asthma in offspring
- Where
- Spain
- Volunteers
- 10,116 people
- Sponsor
- AstraZeneca
Category 3 Study (Non-interventional Research)
Evaluation of an Environmental Counsellor's Home Stay in Children Treated for Asthma or Allergic Rhinitis Via a Standardized Medical Questionnaire Randomized Controlled Superiority Trial in Parallel Arms, Multicentric (EvalPCE)
Assessment of asthmatic children and children with allergic rhinitis at day 0 and 6 months after a home visit by an environmental consultant via standardized medical questionnaires.
- Trial name
- EvalPCE (NCT04927689)
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Asthma
Acupoint Massage Combined With Ear Point Pressing Beans
Objective: To explore the application effect of acupoint massage combined with ear point pressing beans in the remission stage of asthma.
- Trial name
- NCT06650917
- Testing
- the experiment group were treated acupoint massage combined with ear point pressing beans, the control group were treated with acupoint massage
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hai'an Hospital of TCM001
Asthma
A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
This is a multicenter, randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of subcutaneously administered Xolair as add-on therapy for the treatment of subjects aged 12-75 years old…
- Trial name
- NCT00314574
- Testing
- omalizumab (Xolair), corticosteroids, long-acting beta-agonists
- Volunteers
- 850 people
- Sponsor
- Genentech, Inc.
Asthma
Study to Evaluate the Potential Effect of Benralizumab on the Humoral Immune Response to the Seasonal Influenza Vaccination in Adolescent and Young Adult Patients With Severe Asthma
This is a randomized, double-blind, parallel group, placebo-controlled study designed to investigate the potential effect of a fixed dose of benralizumab administered subcutaneously (SC) on antibody responses following seasonal…
- Trial name
- ALIZE (NCT02814643)
- Testing
- Benralizumab, Seasonal influenza virus vaccine
- Where
- 24 sites in United States
- Volunteers
- 103 people
- Sponsor
- AstraZeneca
Allergic Rhinitis, Asthma
Causal Associations Between Allergic Rhinitis and Asthma
This study investigates the causal relationship between allergic rhinitis and asthma using a bidirectional two-sample Mendelian randomization approach.
- Trial name
- NCT06668974
- Testing
- Mendelian Randomization
- Where
- China
- Volunteers
- 239,607 people
- Sponsor
- Zhibin Xu
Rhinoconjunctivitis With or Without Allergic Asthma
Study to Assess the Safety and Effectiveness of Beltavac® Polymerized With Cat Dander
Non-interventional Study to Assess the Safety and Effectiveness Profile of a SCIT Therapy With Beltavac® Polymerized With Cat Dander in allergic patients
- Trial name
- NCT04207697
- Testing
- Beltavac® Polymerized with cat dander
- Where
- 7 sites in Spain
- Volunteers
- 34 people
- Sponsor
- Probelte Pharma S.L.U.
Sickle Cell Disease, Vitamin D Deficiency
Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether oral vitamin D supplementation can decrease lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Acute Chest Syndrome, Asthma
- Trial name
- NCT01443728
- Testing
- Experimental: Vitamin D3 100,000 IU, Active Comparator: Vitamin D3 12,000 IU
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Gary M Brittenham, MD
Asthma Intermittent, Uncontrolled
Feasibility of an Asthma Online Social Intervention
The goal of this observational study is to test the feasibility and acceptability of an online intervention for people with troublesome asthma in primary care, involving a consultation with a primary care clinician to introduce…
- Trial name
- NCT05829265
- Testing
- A digital social intervention by primary care clinicians.
- Where
- United Kingdom
- Volunteers
- 526 people
- Sponsor
- Queen Mary University of London
Pediatric Asthma
Association Between Activity and PROMIS Pediatric Measures in Children With Asthma
Aim: Determine the association between activity (steps taken) and PROMIS Pediatric measures in order to explore the use of pedometry data to augment PROs in research and clinical care.
- Trial name
- NCT03933540
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Duke University
Infantile Asthma
Non Invasive Evaluation of Bronchial Inflammation in Infants : a Study of the Sputum Cellularity After Hypertonic Saline Induction
Background: Infantile asthma is composed of various phenotypes, however the definition is still based on the clinics. Namely, the infants could be classified as transitory, peristent or late and persistent asthma.
- Trial name
- CYTOASTHME (NCT02245074)
- Testing
- Sputum induction
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Rouen
Allergy, Allergic Asthma
abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies
This is a multicenter, prospective, observational study designed to determine the clinical sensitivity and specificity of the Abionic IVD CAPSULE Allergic Asthma panel performed on Abionic's abioSCOPE device using K3-EDTA…
- Conditions
- Allergy, Allergic Asthma, Allergy to Cats, Allergy to House Dust
- Trial name
- NCT04442932
- Testing
- Blood Collection
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abionic SA
Severe Asthma
Observational Retrospective Study To Characterize and Assess Clinical Outcomes of Patients Receiving Tezepelumab in the Framework Of Use in Special Situations Prior to Commercialisation in Spain
The aim of this study is to provide the first results on the use of tezepelumab under clinical practice conditions in severe asthma patients who participated in the "foreign medication supply" program in Spain.
- Trial name
- T-ROSS (NCT06487065)
- Where
- 14 sites in Spain
- Volunteers
- 33 people
- Sponsor
- AstraZeneca
Asthma
Asthmatuner a Self-management App for Asthma: A Randomized Controlled Multicentre Trial
Primary aim: Evaluating the effect of Asthmatuner on patients´ self-reported asthma control test (ACT/C-ACT)compared with conventional asthma management.
- Trial name
- Asthmatuner (NCT02571309)
- Testing
- Asthmatuner
- Where
- Sweden
- Volunteers
- 77 people
- Sponsor
- Karolinska Institutet
Pediatric Asthma
The Airports, Air Quality, and Asthma (AAA) Study
For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening.
- Trial name
- NCT07047430
- Testing
- Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington