Clinical trials: asthma
Asthma
Safety, Tolerability and Pharmacokinetics of Inhaled Laninamivir Octanoate TwinCaps® DPI in Adults With Chronic Asthma
This is a single centre, randomized, double-blind, placebo-controlled, single ascending dose study, in which the safety and pharmacokinetics of laninamivir octanoate administered by inhalation via the TwinCaps® DPI will be…
- Trial name
- NCT02022761
- Testing
- Laninamivir octanoate
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Biota Scientific Management Pty Ltd
Asthma
Study on BI 54903 (Inhaled Corticosteroid) Administered Once Daily or Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Short Acting Beta-2 Agonist (SABA) Therapy Alone
The aim of this study is to assess and compare efficacy and safety of BI 54903 at doses of very low dose twice daily (b.i.d) and low dose once daily (evening dosing) and placebo over an 12-week treatment period in asthmatic…
- Trial name
- NCT01458886
- Testing
- BI 54903 MD, BI 54903
- Sponsor
- Boehringer Ingelheim
Asthma
A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes
TriMaximize, a non-interventional trial aims to collect prospective, longitudinal data from asthma patients under routine care, for whom their treating physician has decided to prescribe Trimbow®…
- Trial name
- TriMaximize (NCT04902573)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 147 people
- Sponsor
- Chiesi UK
Overweight, Obesity
Enhanced Primary Care and Technology for Children With Chronic Disease
Using technology alongside a pediatric chronic disease specialist and behavior specialist, the investigators are planning to help care for and coordinate the healthcare of children with chronic diseases, particularly childhood…
- Conditions
- Overweight, Obesity, Asthma
- Trial name
- NCT02490566
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Asthma
Dose Finding Trial to Assess the Efficacy and Safety of SOTB07 in Persistent Asthma
This study is a dose finding trial to assess the efficacy and safety of SOTB07 in persistent asthma.
- Trial name
- NCT00936624
- Testing
- SOTB07, montelukast
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- SK Chemicals Co., Ltd.
Acute Respiratory Infection, Asthma Exacerbations
Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations
REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other…
- Trial name
- REMASK (NCT06885229)
- Testing
- FloMask - reuseable face mask
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma
Comparing Salmeterol/Fluticasone Easyhaler and Seretide Diskus (SAIMI)
The purpose of this study is to compare absorption of salmeterol and fluticasone from Salmeterol/fluticasone Easyhaler test products to the commercially available product Seretide Diskus
- Trial name
- NCT03238482
- Testing
- salmeterol-fluticasone
- Where
- Finland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Asthma
A Study of the Safety and Efficacy of Tacrolimus Inhalation Aerosol in Subjects With Persistent Asthma
The purpose of this study is to determine the safety and effectiveness of tacrolimus inhalation aerosol in subjects with persistent asthma.
- Trial name
- NCT00116103
- Testing
- Tacrolimus Inhalation Aerosol
- Where
- 21 sites in United States
- Sponsor
- Astellas Pharma Inc
Asthma
Investigating the Effects of QVM149 on MRI Ventilation Defects
The purpose of this study is to compare treatment with QVM149, an inhaler that contains three types of asthma medications compared to an inhaler that contains two types of asthma medications.
- Trial name
- XPERTT (NCT04206761)
- Testing
- QVM149, High Dose Dual Therapy (ICS/LABA)
- Where
- Canada
- Sponsor
- Dr. Grace Parraga
Allergic Conditions
Efficacy and Safety of LAIS® Mites Sublingual Tablets
Evaluation of the efficacy and safety of SLIT with LAIS® Mites Sublingual tablets compared to standard drug treatment in patients aged over 60 years suffering from house dust mite (HDM) induced allergic rhino-conjunctivitis…
- Trial name
- korLAIS (NCT02277483)
- Testing
- LAIS®
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Moderate to Severe Asthma
PULmonary Stimulation for Asthma Relief
This study aims to assess the safety and efficacy of Pulmonary Neuromodulation in patients suffering from moderate to severe asthma
- Trial name
- PULSAR (NCT07709754)
- Testing
- Spinal Cord Stimulation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Spiro Medical, Inc.
Chronic Rhinosinusitis Without Nasal Polyps, Asthma
Adherence in Global Airways
There is a strong case for treating diseases of both the upper and lower airways (global airways) simultaneously because they share the same inflammatory mechanisms.
- Conditions
- Chronic Rhinosinusitis Without Nasal Polyps, Asthma, Chronic Rhinosinusitis With Nasal Polyps, Chronic Rhinosinusitis (Diagnosis)
- Trial name
- AIR2022 (NCT05553951)
- Testing
- Controlgroup, Intervention
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Christiane Haase
Dental Caries, Periodontal Diseases
Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis
The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline.
- Trial name
- NCT05631197
- Testing
- Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Asthma
Effect of Montelukast on Remodelling Markers in Asthmatic Children
Airway smooth muscle cell layer thickening and sub epithelial fibrosis, key allergen-induced airway remodelling features not modulated by corticosteroids, are reversible by CysLT1 receptor blockade therapy in animals.
- Trial name
- MORACH (NCT00875082)
- Testing
- Montelukast
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Chronic Rhinosinusitis
Validation of the Chinese Version of the Sinus and Nasal Quality of Life Survey (SN-5)
The purpose of our study was to validate the Chinese version of the Sinus and Nasal Quality of Life Survey (SN-5)and correlation with the incidence of pediatric obstructive sleep apnea and asthma.
- Trial name
- NCT04836403
- Testing
- Sinus and nasal quality of life survey questionnaire (SN-5)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Asthma
Assess Bronchodilator Effect and Safety of Two Doses of QVM149 Compared to a Fixed Dose Combination of Salmeterol/Fluticasone in Patients With Asthma.
The purpose of this study is to assess peak FEV1 of two doses of QVM149 compared to a fixed-dose combination of salmeterol/fluticasone (50/500μg b.i.d.) and to characterize the respective 24 hour bronchodilator effect profiles in…
- Trial name
- NCT03063086
- Testing
- QVM149 150/50/80 μg o.d., QVM149 150/50/160 μg o.d., salmeterol/fluticasone FDC 50/500 μg b.i.d.
- Where
- 12 sites in Bulgaria, China and 4 more
- Volunteers
- 116 people
- Sponsor
- Novartis Pharmaceuticals
Hay Fever, Asthma
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
The clinical trial aimes to evaluate multiple large language models in respiratory disease consultations by comparing their performance to that of human doctors across three major medical consultation scenarios.
- Conditions
- Hay Fever, Asthma, Acute Upper Respiratory Infection, Pulmonary Embolism
- Trial name
- EPLLMMRDC (NCT06457269)
- Testing
- Diagnosis by three human doctors, Diagnosis by ChatGPT-3.5 (with search capabilities), Diagnosis by ChatGPT-3.5 (without search capabilities)
- Where
- China
- Volunteers
- 703 people
- Sponsor
- North Sichuan Medical College
Asthma, Pneumonia
PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress
This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress.
- Conditions
- Asthma, Pneumonia, Respiratory Distress Syndrome
- Trial name
- NCT03647397
- Testing
- Photo Electrochemical Oxidation (PECO) for Air Purification
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Molekule
Asthma
Study of FLUTIFORM® VS Seretide® in Paediatric Subjects With Asthma
Study compares the efficacy and safety of FLUTIFORM® with Seretide® in the treatment of mild to moderate persistent asthma in pediatric subjects.
- Trial name
- NCT00475813
- Testing
- FLUTIFORM® (Formoterol fumarate / Fluticasone propionate)
- Where
- 6 sites in Czechia, France and 4 more
- Volunteers
- 211 people
- Sponsor
- Mundipharma Research Limited
Asthma
Concentrations of Formoterol in Blood and Urine
The purpose of the study is to assess the blood and urine concentrations of inhaled formoterol.
- Trial name
- NCT00914654
- Testing
- inhaled formoterol
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
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