Clinical trials: in Kuwait
Ocular Graft Versus Host Disease
Evaluation of the Safety and Effectiveness of omniLenz in Patient With Ocular Graft vs Host Disease
A case series of patients presented with graft versus host disease with ocular involvement . The study recruited a total of 3 patients who were referred to cornea clinic of Farwaniya Hospital, Kuwait between April 2022 and April…
- Trial name
- NCT07066865
- Testing
- omniLenz
- Where
- Kuwait
- Volunteers
- 3 people
- Sponsor
- Farwaniya Hospital
Low Birth Weight, Small for Gestational Age (SGA)
Improving Aspirin Prescription Rates in Outpatient Clinic
Ρrееςlаmpѕia is a syndrome characterised by the new onset of hуреrtеnѕion plus proteinuria, end-organ dysfunction, or both after 20 weeks of gestation. It complicates 3-5% of pregnancies.
- Conditions
- Low Birth Weight, Small for Gestational Age (SGA), Preeclampsia (PE), Prevention &Amp; Control
- Trial name
- NCT06694233
- Testing
- Aspirin prescription on outpatient basis
- Where
- Kuwait
- Volunteers
- 300 people
- Sponsor
- Cairo University
Arrhythmia, Sinus Node Disease
PANORAMA Observational Study
To construct a computerized database of national profiles and epidemiological data on patients wearing Medtronic implantable pacemakers and cardioverter defibrillators (both with or without cardiac resynchronization therapy)…
- Conditions
- Arrhythmia, Sinus Node Disease, Heart Failure, Heart Block
- Trial name
- NCT00382525
- Testing
- Cardiac Rhythm Management device
- Where
- 27 sites in Belgium, India and 4 more
- Volunteers
- 8,586 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Type 1 Diabetes (T1D), Type 1 Diabetes Mellitus (T1DM)
Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes
Type 1 diabetes is becoming more common in Kuwaiti and Arab adolescents. Many young people with this condition struggle to keep their blood glucose levels under control, which can lead to diabetes-related complications and affect…
- Trial name
- NCT06984133
- Testing
- Structured education program
- Where
- Kuwait
- Volunteers
- 128 people
- Sponsor
- Dasman Diabetes Institute
Histopathology, Screening Tool
Improving Outpatient Endometrial Biopsy Results
Pipelle is the most commonly used outpatient endometrial biopsy device. Pipelle endometrial biopsy can diagnose 90% of endometrial cancer cases.
- Conditions
- Histopathology, Screening Tool, Techniques
- Trial name
- NCT06694246
- Testing
- Improving technique, Using hysteroscopy in candidate patients, Analgesia
- Where
- Kuwait
- Volunteers
- 400 people
- Sponsor
- Cairo University
Carcinoma, Non-Small-Cell Lung
A Multicountry, Multicentre, Non-interventional, Retrospective Study to Determine Real-world Treatment Patterns and Associated Outcomes After First Line Osimertinib in Patients With Advanced and Metastatic NSCLC EGFRm in the GCC Region
A Multicountry, Multicenter, Non-interventional, Retrospective Study to determine Real-world treatment patterns and associated outcomes after FIRST LINE Osimertinib in patients with advanced and Metastatic NSCLC harboring…
- Trial name
- TREASURE (NCT06039683)
- Where
- 7 sites in Kuwait, Qatar and 2 more
- Volunteers
- 54 people
- Sponsor
- AstraZeneca
Hemophilia A With Inhibitor
rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A
A chart review study of patients with haemophilia A with inhibitors treated with rFVIIIFc (Elocta®) for immune tolerance induction.
- Trial name
- NCT03951103
- Testing
- rFVIIIFc
- Where
- 18 sites in France, Germany and 6 more
- Volunteers
- 44 people
- Sponsor
- Swedish Orphan Biovitrum
Outcomes of Cyclosporine Eye Drops in Herpetic Keratitis
Clinical Outcomes of Cyclosporine Eye Drops in Management of Herpetic Keratitis
Objective: To compare the additive effect of topical cyclosporine A 0.05% eye drops to prednisolone eye drops, with topical prednisolone acetate 1% eye drops alone in treatment of herpetic stromal keratitis.
- Trial name
- NCT05720715
- Testing
- cyclosporine A 0.05% eye drops
- Where
- Kuwait
- Volunteers
- 30 people
- Sponsor
- Farwaniya Hospital
Sickle Cell Disease
Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India
This is a multicenter, prospective, single-arm observational non-interventional study (NIS), which will be conducted in various countries in the Middle East and India.
- Trial name
- SPOTLIGHT (NCT05020873)
- Testing
- Crizanlizumab
- Where
- 5 sites in Bahrain, Kuwait and 2 more
- Volunteers
- 44 people
- Sponsor
- Novartis Pharmaceuticals
Alveolar Cleft, Alveolar Ridge Cleft
Evaluation of Shell Technique in Secondary Alveolar Cleft Grafting
This study aims to evaluate the sufficiency of Khoury shell technique for reconstruction of alveolar cleft. Khoury technique was carried out using cortical bone shell fixed away from alveolar bone using two micro-screws, which…
- Trial name
- Alveolar cleft (NCT06304376)
- Testing
- Alveolar ridge grafting
- Where
- Kuwait
- Volunteers
- 14 people
- Sponsor
- October 6 University
Diabetic Ketoacidosis
Association of Systemic Immune-inflammation Index and Severity of Diabetic Ketoacidosis in Type 1 Diabetes Mellitus
Diabetic ketoacidosis (DKA) is the most serious metabolic complication of type 1 diabetes mellitus (T1DM). Insulin deficiency and inflammation play a role in the pathogenesis of DKA.
- Trial name
- NCT06251895
- Testing
- DKA protocol
- Where
- Kuwait
- Volunteers
- 241 people
- Sponsor
- Jahra Hospital
Locally Advanced Head and Neck Cancer
Concomitant Immune Check Point Inhibitor With Radiochemotherapy in Head And Neck Cancer
Background: Locally advanced head and neck cancer (HNC) is a challenge as, in spite of initial good control with chemoradiation, the majority of patients fails systemically.
- Trial name
- NCT03532737
- Testing
- Pembrolizumab
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Kuwait Cancer Control Center
Root Canal Obturation, Root Canal Filling
Outcome of SBO With Calcium Silicate Sealer vs WVC With Resin Based Sealer
A single blinded randomized controlled trial. 212 subjects (teeth), 106 in each of the 2 groups will be recruited from the patients referred to Kuwait Board of Endodontics for primary root canal treatment.
- Conditions
- Root Canal Obturation, Root Canal Filling, Sealer-based Obturation, Randomized Clinical Trial
- Trial name
- NCT04753138
- Testing
- TotalFill Bioceramic Sealer, AH+ Sealer
- Where
- Kuwait
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Dermatitis Atopic
A Study to Assess the Disease Control of Moderate to Severe Atopic Dermatitis in Male and Female Participants of Atleast 12 Years Old Receiving Dupilumab Injections in Gulf Countries
Primary objective: To assess the disease control of moderate to severe atopic dermatitis in patients aged 12 years and above treated with dupilumab therapy using Atopic Dermatitis Control Tool (ADCT) after 24 weeks of treatment.
- Trial name
- AD-impaCT (NCT05214326)
- Where
- 3 sites in Kuwait, Saudi Arabia and 1 more
- Volunteers
- 187 people
- Sponsor
- Sanofi
Severe Acute Respiratory Syndrome Coronavirus 2
Treatment Of CORONAVIRUS DISEASE 2019 (COVID-19) With Anti-Sars-CoV-2 Convalescent Plasma (ASCoV2CP)
This treatment protocol is designed to provide convalescent plasma as a therapeutic option for patients diagnosed with and hospitalized for COVID-19 with symptoms ranging from mild to life-threatening.
- Trial name
- NCT04360486
- Testing
- Anti-Sars-CoV-2 Convalescent Plasma
- Where
- 38 sites in United States, Afghanistan and 6 more
- Sponsor
- U.S. Army Medical Research and Development Command
Management of Punctal Stenosis
Topical Cyclosporin A 0.05% Eye Drops for Management of Symptomatic Acquired Punctal Stenosis. A Prospective, Controlled Clinical Study.
A prospective, controlled, interventional clinical study, includes all patients (16 years) with symptomatic epiphora and diagnosed with grade 1 or grade 2 acquired punctal stenosis.
- Trial name
- NCT05771012
- Testing
- 0.05% cyclosporin (Restasis®, Allergan Inc), mini-monoka stent
- Where
- Kuwait
- Volunteers
- 42 people
- Sponsor
- Farwaniya Hospital
Neurodevelopmental Disorders, Cerebral Palsy
Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy
The purpose of this study is to determine the effects of Central Nervous System Stimulants, represented by Methylphenidate and Modafinil, compared to placebo control on motor performance in children with Cerebral Palsy.
- Trial name
- CP (NCT05675098)
- Testing
- Methylphenidate, Modafinil
- Where
- Kuwait
- Volunteers
- 30 people
- Sponsor
- Kuwait University
Cesarean Delivery
Carbetocin Compared To Oxytocin During Cesarean Delivery
As both oxytocin and carbetocin are used daily in obstetric units all over the world, the investigators find it compelling to investigate whether the hemodynamic and myocardial effects of oxytocin and carbetocin are comparable in…
- Trial name
- NCT05758012
- Testing
- oxytocin, Carbetocin
- Where
- Kuwait
- Volunteers
- 260 people
- Sponsor
- Assiut University
Retention, Time
Efficacy and Retention of Sealants Placement Using Two Isolation Systems
The trial aimed to evaluate the sealant retention, patient's preference and chair time needed during pit and fissure sealant placement under two isolation techniques [Dryshield system (DS) and cotton roll isolation (CRI)] in a…
- Conditions
- Retention, Time, Patient Preference
- Trial name
- NCT05749991
- Testing
- Dryshield, Cotton roll isolation
- Where
- Kuwait
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Developmental Dysplasia of the Hip
Do All Patients With Congenital Hip Dysplasia Corrected Operatively Need Physiotherapy
Developmental Dysplasia of the Hip (DDH) is a common condition among young children that could range in severity. in most sever cases, surgical intervention is the best choice to correct the hip abnormality with the aim of…
- Trial name
- NCT05238935
- Testing
- prescribed physiotherapy course
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Ministry of Health, Kuwait