Clinical trials: completed, in Nepal
Domestic Violence, Mental Health
Testing Family Intervention to Address Mental Health and Domestic Violence Among Women
Domestic Violence (DV) is a major public health problem in low- and middle-income countries (LMICs) including Nepal, where women often live in extended, multigenerational households, and violence can be perpetrated by the husband…
- Trial name
- DV-MH (NCT07872228)
- Testing
- Multi-component family intervention
- Where
- Nepal
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Possible
Gender-Based Violence, Intimate Partner Violence
GBV Response Training for Health Assistant Students in Nepal
This study evaluated a six-day Gender-Based Violence (GBV) response training for PCL General Medicine (Health Assistant) students in Nepal.
- Conditions
- Gender-Based Violence, Intimate Partner Violence, Health Professions Education
- Trial name
- GBV-HA-RT (NCT07851883)
- Testing
- Six-Day GBV Response Training (WHO LIVES-based)
- Where
- Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Axon Infotech Research Academy Pvt. Ltd.
UGI Bleed
Comparison of Risk Scores in Upper Gastrointestinal Bleeding
The goal of this prospective observational study is to compare the Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score in predicting outcomes among patients with upper gastrointestinal bleeding (UGIB).
- Trial name
- NCT07819942
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Corneal Ulcer
Village Integrated Eye Workers Trial
VIEW is a community-randomized trial designed to determine whether it is possible to prevent corneal ulcers on a large scale. The study compares the incidence of corneal ulceration between villages in which volunteers are trained…
- Trial name
- VIEW (NCT01969786)
- Testing
- Corneal ulcer prevention program
- Where
- Nepal
- Volunteers
- 223,671 people
- Sponsor
- University of California, San Francisco
Mental Health
Stress Management Training for Nursing Professionals in a Tertiary Care Center in Nepal
The goal of this clinical trial is to learn if stress management programs can help alleviate existing and prevent future symptoms of stress in nursing professionals working in a tertiary care center in Nepal.
- Trial name
- NCT06438016
- Testing
- Stress Management Training
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Dhulikhel Hospital
Post Partum Depression
Sensing Technologies for Maternal Depression Treatment in Low-Resource Settings
In certain low- and middle- income country settings, there is a disproportionate level of untreated postpartum depression that presents both acute and long-term risks to a mother's well-being.
- Trial name
- StandStrong (NCT06253676)
- Testing
- Problem Management Plus (PM+)
- Where
- Nepal
- Volunteers
- 121 people
- Sponsor
- George Washington University
Oral Hygiene, Visually Impaired Persons
Effectiveness of Audio-Tactile Performance Technique With Sing-Along Lyrics on Oral Hygiene Instruction to Visually Impaired Individuals
The goal of this match-pair randomized study is to compare the effectiveness of the standard Audio-Tactile Performance (ATP) technique with a song-based adaptation (ATP/S) in teaching oral hygiene in visually impaired individuals…
- Trial name
- NCT07585448
- Testing
- ATP, ATP with song
- Where
- 2 sites in Nepal
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Laparoscopic Cholecystectomy, Ultrasonography
Ultrasonography vs Intraoperative Laparoscopic Cholecystectomy for Gall Stone Disease
This research is designed to correlate between intraoperative status of gallstone disease patients with their USG findings. The key question it aims to answer is: Does the ultrasonography predict laparoscopic cholecystectomy will…
- Conditions
- Laparoscopic Cholecystectomy, Ultrasonography, Difficult Surgery
- Trial name
- NCT07530874
- Testing
- laparoscopic cholecystectomy
- Where
- Nepal
- Volunteers
- 130 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Internet Addiction Prevention Among Higher Secondary School Students
Effect of TPB-Based Educational Intervention on Preventing Internet Addiction in Students
This quasi-experimental study evaluated a Theory of Planned Behavior-based educational intervention among higher secondary students in Kathmandu, Nepal.
- Trial name
- NCT07504978
- Testing
- Educational Intervention Package based on the Theory of Planned Behavior
- Where
- Nepal
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Manish Rajbanshi
Undernutrition
Enhancing Milk Consumption by Vulnerable Household Members in Rural Nepal
Diet quality is generally poor in rural Nepal, especially among vulnerable household members. Consumption of milk (and other animal source foods [ASF]) could contribute to improvements in diet quality.
- Trial name
- NCT05525429
- Testing
- Nutrition Education
- Where
- Nepal
- Volunteers
- 1,873 people
- Sponsor
- Tufts University
Typhoid Fever
The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial)
Typhoid and paratyphoid (enteric) fever affects more than 11 million children and adults globally each year including 7 million in South Asia.
- Trial name
- ACT-South Asia (NCT04349826)
- Testing
- Azithromycin, Cefixime
- Where
- Nepal
- Volunteers
- 2,150 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Pneumonia, Childhood Pneumonia
Diagnostic Accuracy of Lung Ultrasound for Pneumonia Diagnosis in Children
Chest X-ray is historically being used as an imaging standard to aid to the diagnosis of childhood pneumonia, however, the evidence does not support it as a perfect imaging tool.
- Trial name
- LUS (NCT07331311)
- Testing
- LUS as a chest imaging tool
- Where
- Nepal
- Volunteers
- 320 people
- Sponsor
- Nagasaki University
CBD Stone
Re-use of Ambu aScope During Exploration of the Common Bile Duct for Stones in Low-Resource Settings- a Retrospective Study
Various methods confirm stone clearance during surgical exploration of bile duct, but choledochoscopy is considered the most effective. However, choledochoscopes are expensive and often unavailable in low-resource settings.
- Trial name
- NCT07285447
- Testing
- Ambu aScope for visualization of biliary tree during exploration of CBD for stone
- Where
- Nepal
- Volunteers
- 75 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Gene Therapy, Hemophilia B
Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy
Gene therapy is a paradigm-shifting treatment for hemophilia B patients, particularly in resource-limited countries where factor availability remains low.
- Trial name
- NCT05044845
- Testing
- Interview
- Where
- 6 sites in United States, Nepal and 4 more
- Volunteers
- 150 people
- Sponsor
- St. Jude Children's Research Hospital
Peptic Ulcers
Risk Factors Affecting Mortality in Perforated Peptic Ulcer
Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery…
- Trial name
- NCT07050199
- Testing
- Emergency laparotomy
- Where
- Nepal
- Volunteers
- 85 people
- Sponsor
- Maharajgunj Medical Campus
Keloids
Efficacy and Safety of Intralesional 5-Fluorouracil and Triamcinolone Acetonide in Keloids and Hypertrophic Scars
Pathological scars like keloids and hypertrophic scars (HTS's) cause significant aesthetic, symptomatic and psychological issues to patients. Treatment is challenging with no universally accepted "gold standard" method.
- Trial name
- NCT07034482
- Testing
- Intralesional Triamcinolone 5 mg/ml, Intralesional 5-fluorouracil
- Where
- Nepal
- Volunteers
- 41 people
- Sponsor
- Maharajgunj Medical Campus
Mental Disorder, Depressive Disorder
Reducing Stigma Among Healthcare Providers (RESHAPE-cRCT)
A growing number of trials have demonstrated treatment effectiveness for mental illness by non-specialist providers, such as primary care providers, in low-resource settings.
- Conditions
- Mental Disorder, Depressive Disorder, Anxiety Disorder, Alcohol Use Disorder
- Trial name
- RESHAPE-cRCT (NCT04282915)
- Testing
- Reducing Stigma among Healthcare Providers (RESHAPE), mental health Gap Action Programme
- Where
- Nepal
- Volunteers
- 8,705 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cardiac Surgery, Cardiac Surgery Requiring Cardiopulmonary Bypass
Clinical Outcomes Between Pulsatile and Non-Pulsatile Flow During Cardiopulmonary Bypass
The aim of this prospective, randomized study was to compare clinical outcomes of Pulsatile and non-pulsatile flow during Cardiopulmonary Bypass.
- Trial name
- NCT07009730
- Testing
- Bypassing Agents
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Gallstone
Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis
Subtotal cholecystectomy (STC) is a valuable technique when severe inflammation, fibrosis, or anatomical variations obscure the critical view of safety essential for identifying the cystic duct and artery.
- Trial name
- NCT06969144
- Testing
- cholecystectomy
- Where
- Nepal
- Volunteers
- 1,149 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Surgery With General Anesthesia
Diagnosis and Its Procedural Pattern Among Patients Who Underwent Surgery at Aloha Medical Mission in Dhankuta, 2018
This was a retrospective, cross-sectional study of the Aloha medical mission in 2018, which involved analyzing recorded data on the sociodemographic profiles of patients, diseases, and surgical procedures.
- Trial name
- Diagnosis and (NCT06969157)
- Testing
- Surgery
- Where
- Nepal
- Volunteers
- 225 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.