Clinical trials: in Pakistan
Treatment
Evaluating the Effectiveness of an Adapted-Dialectical Behavior Therapy (A-DBT)
Adapted-Dialectical Behavioral Therapy (A-DBT) Adolescence Manual (Urdu version) An A-DBT Adolescence Urdu version Manual was used consisted of techniques related to mindfulness, emotion regulation, interpersonal effectiveness…
- Trial name
- A-DBT (NCT07883408)
- Testing
- Adapted Dialectical Behavioral Therapy (A-DBT)
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Islamic University, Islamabad
Dental Anxiety in Children, Child Behaviour
Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide Monotherapy
The rationale of this trial is to evaluate whether combining intranasal atomized midazolam with nitrous oxide offers better behavior management leading to successful treatment completion in comparison with using nitrous oxide…
- Trial name
- NCT07876024
- Testing
- Midazolam (Intranasal), Nitrous oxide/oxygen inhalation sedation alone
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Child Development
Effects of Five Stones Pebble Game on In-Hand Manipulation and Hand Writing Skills of School-going Children
This randomized controlled trial will be conducted on 26 school-going children (aged 8-12 years) from The City School and Classic School System, randomly assigned to a traditional play group or an unstructured gameplay group…
- Trial name
- NCT07872293
- Testing
- Five Stones Pebble Game, Unstructured Play Group
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Duchenne Muscular Dystrophy (DMD), Spinal Muscular Atrophy (SMA)
Self-Efficacy Enhancement Among Online Support Group of Primary Caregivers of Children With Neuro Muscular Dystrophy
The goal of this clinical trial is to learn if providing a multicomponent intervention improves the confidence of caregivers of children with DMD or SMA.
- Trial name
- SEE-NMD (NCT07356063)
- Testing
- Multicomponent Intervention
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
No Disease or Condition is Being Studied
French Contrast Versus Oregon Circuit Training in Competitive Football Players
This randomized, two-arm, parallel-group clinical trial is designed to compare French Contrast Training (FCT) with Oregon Circuit Training (OCT) for improving explosive strength, lower-limb power, and agility in competitive…
- Trial name
- FCT-OCT (NCT07865702)
- Testing
- French Contrast Training, Oregon Circuit Training
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Superior University
Maternal Nutrition, Child Nutrition
Climate-Responsive Nutrition, WASH, and Heat Counselling for Maternal and Child Health in Sindh, Pakistan
The goal of this clinical trial is to evaluate whether a climate- and gender-responsive integrated package of nutrition, hygiene (WASH), and heat-adaptation counselling can improve maternal and child health and nutrition outcomes…
- Trial name
- IGNIT3 (NCT07819994)
- Testing
- Training of Lady Health Workers (LHWs), Training of Healthcare Providers (HCPs) at Facilities
- Where
- Pakistan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Fitness
Effects of Rebound Therapy on School Going Children
The study aims to find out if rebound therapy is an effective way to improve children's overall physical fitness in schools.Many children spend long hours sitting in classrooms, which can negatively affect their health and…
- Trial name
- NCT07854587
- Testing
- Physical education activities., Physical education activities with rebound therapy.
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Malaligned Teeth, Crowding
A Prospective , Split-mouth, Clinical Study of Orthodontic Titanium Miniscrews With Machined and Acid-etched Surfaces.
Primary goal of this study to check the stability of miniscrews used in orthodontic treatment in order to evaluate the success of the treatment.
- Trial name
- NCT07662434
- Testing
- miniscrews placement
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Child Development
Effects of Animal Fun Program in Children With DCD.
This randomized clinical trial investigates the effects of animal fun program on motor skills in children with developmental coordination disorder.
- Trial name
- NCT07244055
- Testing
- animal fun program, control group
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Child, Only
Effects of Traditional Game in School Going Children
This randomized controlled trial examines whether regular participation in the traditional game Kho-Kho improves agility and reaction time in school-aged children.
- Trial name
- NCT07440771
- Testing
- KH0-KHO game, free play activity
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pes Planus
Sensorimotor Technique on Navicular Drop in School Going Children
The goal of the study is to determine effects of sensorimotor technique (SMT) program with short foot exercises on navicular drop and foot posture in school going children in both male and female students of age 7-12.
- Trial name
- NCT07576504
- Testing
- sensorimotor technique, short foot exercise
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Neuromuscular Training, Dynamic Balance
Comparative Effects of Advanced Neuromuscular and Dynamic Balance Training Among Hockey Players
This randomized clinical trial aims to compare the effects of advanced neuromuscular training and dynamic balance training on strength, balance, and functional performance among male hockey players.
- Conditions
- Neuromuscular Training, Dynamic Balance, Athletic Performance
- Trial name
- NCT07845968
- Testing
- ADVANCED NEUROMUSCULAR TRAINING, DYNAMIC BALANCE TRAINING
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Artificial Intelligence (AI) in Diagnosis, Decision Making
Training Diagnostic Specialists to Use Artificial Intelligence Safely: The DISCORD-Dx Study
This randomized study evaluated whether a structured reasoning strategy called DISCORD-Dx could help specialist doctors use artificial intelligence (AI) recommendations more safely during diagnostic decision-making.
- Trial name
- DISCORD-Dx (NCT07844889)
- Testing
- DISCORD-Dx Training, Conventional AI-Literacy Training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sara Reza
Dysmenorrhea
Effects of Sacral Release Technique and Lumbar Mobilization in Primary Dysmenorrhea.
The aim of this study is to determine the comparative effects of sacral release technique and lumbar mobilization in pain, symptoms severity and quality of life in primary dysmenorrhea.
- Trial name
- NCT07576231
- Testing
- SACRAL RELEASE TECHNIQUE, LUMBAR MOBILIZATION
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Adult
Effectiveness of AI-Assisted Antibiotic Prescribing
This randomized controlled trial aims to evaluate the impact of providing LLM access to physicians on antibiotic prescribing appropriateness, using a composite outcome instrument, the Antibiotic Prescribing Appropriateness Score…
- Trial name
- NCT07833293
- Testing
- ChatGPT
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Bracket Failure, Bracket Bonding
Comparison of Bond Failure Rate of Orthodontic Brackets Bonded With V-Prep and Resin-Modified Glass Ionomer Cement Versus Conventional Acid-Etch Composite Resin
Ethical approval will be obtained by the FUSH and informed consent will be obtained from individual patients/guardians in writing.
- Conditions
- Bracket Failure, Bracket Bonding, RMGIC, Conventional Bracket Bonding
- Trial name
- NCT07828431
- Testing
- V-Prep and Resin-Modified Glass Ionomer Cement, Conventional Acid-Etch Composite Resin
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Malocclusion of Anterior Teeth, Malocclusion in Children
Patient-Reported Outcomes for Different Orthodontic Thermoplastics Used in Clear Aligners
Clear aligner therapy is an esthetic orthodontic treatment modality that uses removable thermoplastic trays to correct dental alignment.
- Conditions
- Malocclusion of Anterior Teeth, Malocclusion in Children, Malocclusion Class II
- Trial name
- NCT07790315
- Testing
- Device / orthodontic clear aligner material
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Social Media Addiction
Breaking the Cycle of Social Media Addiction: Efficacy of a 4-STEP Training Program in Reducing Cognitive Fatigue, Psychological Distress, Academic Procrastination, and Burnout Among Adolescents
The goal of this clinical trial is to evaluate the effectiveness of the 4-Step Training Program for Social Media Addiction (4-STEP-TPS) in reducing social media addiction, cognitive fatigue, psychological distress, academic…
- Trial name
- 4-STEP (NCT07821502)
- Testing
- 4-STEP-TPS
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Undernutrition
Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Young Children
Nutrition is essential for a child's growth, brain development, and protection from disease. While breastmilk provides the best nutrition for young infants, children older than six months may not get all the nutrients they need…
- Trial name
- NCT07451951
- Testing
- Medium-quantity lipid-based nutrient supplement (MQ-LNS), Small-quantity lipid-based nutrient supplement (SQ-LNS)
- Where
- 2 sites in Pakistan
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- Aga Khan University