Clinical trials: sponsored by University of Pittsburgh
Healthy
Pregnancy 24/7 Offspring Study
There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for…
- Trial name
- NCT07172880
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kara Whitaker
Down Syndrome, ADHD
Evaluating Treatment of ADHD in Children With Down Syndrome
Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children.
- Trial name
- TEAM-DS (NCT04219280)
- Testing
- Quillivant XR
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myotonic Dystrophy, Duchenne Muscular Dystrophy
Biomarker Development for Muscular Dystrophies
Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies.
- Conditions
- Myotonic Dystrophy, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy
- Trial name
- NCT05019625
- Where
- 5 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3
Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb
Spinal cord stimulation (SCS) has shown remarkable efficacy in restoring motor function in people with spinal cord injury by recruiting afferent input to enhance the responsiveness of spared neural circuits to residual cortical…
- Conditions
- Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy 4
- Trial name
- NCT06300996
- Testing
- Spinal Cord Stimulator (Octopolar Medtronic Vectris Leads)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Marco Capogrosso
Feasibility, Diet, Healthy
Super Chef - an Online Program Promoting the Mediterranean Dietary Pattern to Lower Income Families
Given the limited effectiveness of single food group-targeted interventions to enhance child nutrition, a key component of current and future health, innovative approaches are needed.
- Trial name
- NCT05863559
- Testing
- Super Chef: Family Fun in the Kitchen!
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Child Development, Child Language
The Pittsburgh Study Early Childhood
The Early Childhood Collaborative of The Pittsburgh Study is a community-partnered, county-wide implementation of programs for children and families from birth through formal school entry to address real-world challenges that…
- Conditions
- Child Development, Child Language, Child Behavior Problem, Parenting
- Trial name
- TPS-ECC (NCT05444205)
- Testing
- Text4Baby or Bright by Text Referral, Nurture Program Warm Referral, Video Interaction Project
- Where
- 5 sites in United States
- Volunteers
- 2,546 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Violence, Physical, Violence, Non-accidental
Community Resiliency Collective Efficacy Intervention
This study will evaluate, via a cluster-randomized controlled trial, the effectiveness of a community-centered intervention that promotes thriving and resiliency to reduce community violence.
- Conditions
- Violence, Physical, Violence, Non-accidental, Violence, Sexual, Violence, Domestic
- Trial name
- NCT05768217
- Testing
- Community Resiliency Collective Efficacy Intervention (CRCEI), Health Education Sessions
- Where
- United States
- Volunteers
- 4,600 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Asthma, COPD
Acoustic Waveform Respiratory Evaluation
The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.
- Conditions
- Asthma, COPD, Cystic Fibrosis, Ciliary Motility Disorders
- Trial name
- AWARE (NCT06512064)
- Testing
- AWARE
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Indiana University
HIV
SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension
The overall purpose of this SEARCH CAB-LA (Cabotegravir Injectable Suspension) randomized extension study is to determine if adding the option of CAB-LA as a prevention choice using a person-centered dynamic choice HIV (human…
- Trial name
- NCT05549726
- Testing
- Cabotegravir Injectable Suspension, Dynamic Choice Delivery Model, Standard of Care
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Severe Maternal Morbidity, Maternal Death
The Effects of Medicaid Policy Interventions on Severe Maternal Morbidity
The goal of this study is to learn about the effects of Medicaid policy interventions on severe maternal morbidity (SMM) and mortality and maternal health. The main questions it aims to answer are: 1.
- Trial name
- NCT05678699
- Testing
- Medicaid healthcare quality interventions (incentive payment and obstetric bundled payment), Doula, Standard Care
- Where
- United States
- Volunteers
- 10,000,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Adolescent Drinking, Cannabis Use
Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)
Brief motivational interviewing intervention to address alcohol use among diverse teens 12-17.
- Trial name
- NCT06699251
- Testing
- Chat, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RAND
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Violence in Adolescence, Racism
Forging Hopeful Futures to Reduce Youth Violence
This cluster-randomized community-partnered study will examine the effectiveness of a racial-, gender-, and economic-justice focused youth violence prevention program called Forging Hopeful Futures with youth ages 13-19.
- Conditions
- Violence in Adolescence, Racism, Adolescent Behavior, Coping Skills
- Trial name
- FHF (NCT05743478)
- Testing
- Forging Hopeful Futures, Wellness Check-ins
- Where
- 2 sites in United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stuttering, Childhood
Speech Signals in Stuttering
The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children…
- Trial name
- NCT05668923
- Testing
- Speech sound stimulation
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adolescent Relationship Abuse, Sexual and Gender Minorities
Caregiver-Adolescent Dating Violence Prevention Intervention Pilot Trial
This is a pilot clinical trial to test an intervention called FLARE, which is an adolescent relationship abuse prevention program for sexual and gender diverse youth and their trusted adults.
- Trial name
- NCT07718022
- Testing
- FLARE, Resource Guide
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Mental Health Issue
Implementation Science to Improve School Ethos for Mental Health
The objective of the study is to identify the challenges and opportunities existing within the school ethos in implementing evidence-based interventions to improve youth mental health and to identify the most appropriate…
- Trial name
- NCT06488404
- Where
- India
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intimate Partner Violence (IPV), Cultural Diversity
Juntos: A Pilot Test of a Dating Violence Intervention for Latine Families
In this trial, we will be pilot-testing a family-based dating violence prevention program for Latine caregivers and adolescents.
- Conditions
- Intimate Partner Violence (IPV), Cultural Diversity, Prevention, Parent
- Trial name
- NCT06672679
- Testing
- Juntos, Resource guide
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh