Clinical trials: Azithromycin
Urethritis
NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)
This study will look at the safety, effectiveness, and tolerability of combination medications for the initial treatment of non-gonococcal urethritis (NGU). NGU is inflammation of the tube that carries urine from the bladder.
- Trial name
- NCT00322465
- Testing
- Doxycycline, Tinidazole, Azithromycin
- Where
- 4 sites in United States
- Volunteers
- 305 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ivermectin, Hydroxychloroquine
A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh
COVID19 is a worldwide pandemic. Hence SARS-CoV-2 is a novel virus; there is no specific medication against it. Like other countries of the world, Bangladesh is also struggling in the case of treatment of this disease.
- Conditions
- Ivermectin, Hydroxychloroquine, COVID19
- Trial name
- NCT04434144
- Testing
- Ivermectin + Doxycycline, Hydroxychloroquine + Azithromycin
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Upazila Health & Family Planning Officer's (UHFPO) Office, Chakoria, Cox's Bazar
Obesity, Induction of Labor Affected Fetus / Newborn
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity increases the risk of pregnancy complications, including among others puerperal infections and cesarean delivery, and risk rises with increasing body mass index (BMI).
- Trial name
- APPOINT (NCT03801252)
- Testing
- Cefazolin, Azithromycin
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nephrotic Syndrome
Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndrome
To compare efficacy and safety of Azithromycin versus control in children with steroid sensitive nephrotic syndrome
- Trial name
- NCT07320612
- Testing
- Azithromycin and steroids, steroids
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Trachoma
Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma
To assess in children the efficacy and safety of 2 dosing regimens of T1225 1.5% eye drops, in comparison to a reference product, single-dose oral azithromycin (AZM) 20 mg/kg, for the treatment of active trachoma.
- Trial name
- NCT00356720
- Testing
- Azithromycin
- Sponsor
- Laboratoires Thea
Bronchopulmonary Dysplasia
Trial II of Lung Protection With Azithromycin in the Preterm Infant
The hypothesis of this study is that administration of azithromycin to ventilated premature infants will decrease the incidence and severity of BPD.
- Trial name
- NCT00319956
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Hubert Ballard
Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
The objective was to determine if a single 60 mg/kg dose of azithromycin SR was as safe and effective as a 10-day regimen of amoxicillin (45 mg/kg/day, given in divided doses every 12 hours) when used to treat children with strep…
- Trial name
- NCT00643149
- Testing
- amoxicillin, azithromycin SR
- Where
- 46 sites in United States, Canada and 3 more
- Volunteers
- 693 people
- Sponsor
- Pfizer
Trachoma
Azithromycin in Control of Trachoma II
Trachoma is the world's leading cause of preventable blindness. This disease, caused by Chlamydia trachomatis, is endemic in many parts of the developing world.
- Trial name
- NCT00286026
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bronchopulmonary Dysplasia
TINN2: Treat Infection in NeoNates 2
The aim of the TINN2 study is to evaluate the efficacy of azithromycin in prevention of bronchopulmonary dysplasia in preterm neonates.
- Trial name
- TINN2 (NCT02282176)
- Testing
- Azithromycin
- Where
- 16 sites in Belgium, France and 7 more
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Bronchiolitis Obliterans Syndrome
Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation
This study aims to determine whether or not early spirometric detection and management of obstructive lung disease with combined fluticasone/azithromycin/montelukast therapy (FAM) can attenuate declining lung function, prevent…
- Trial name
- NCT03072849
- Testing
- Pulmonary function testing, FAM Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cystic Fibrosis
Continuous Azithromycin in Cystic Fibrosis Patients Beyond Two Years
Azithromycin is an antibiotic currently prescribed continuously in cystic fibrosis patients. It was shown that this treatment taken every day or every week for 12 months, can improve the respiratory state of patients.
- Trial name
- AZITHRO (NCT02803944)
- Testing
- Azithromycin
- Where
- France
- Volunteers
- 2,055 people
- Sponsor
- Hospices Civils de Lyon
Yaws
Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea
The trial that the investigators are proposing is a pilot study to determine the effect of the new WHO-yaws eradication strategy in Lihir Island (population 18,000), Papua New Guinea.
- Trial name
- YESA-13 (NCT01955252)
- Testing
- Azithromycin
- Where
- Papua New Guinea
- Volunteers
- 16,000 people
- Sponsor
- Lihir Medical Centre
Yaws
Comparison of Two Different Doses of Azithromycin for Treatment of Yaws
The study will be a single blinded, randomized, controlled open label non-inferiority phase III, trial with two parallel groups, conducted in Ghana and Papua New Guinea (PNG).
- Trial name
- NCT02344628
- Testing
- Azithromycin
- Where
- 7 sites in Ghana, Papua New Guinea and 1 more
- Volunteers
- 583 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Plasmodium Falciparum Infection
Chloroquine Alone or in Combination for Malaria in Children in Malawi
Malaria is a sickness caused by a germ that can get into a person's body when a mosquito bites them. It can cause fever, headache, body aches and weakness. It can even cause death, especially in children.
- Trial name
- NCT00379821
- Testing
- Atovaquone-proguanil, Artesunate, Azithromycin
- Where
- Malawi
- Volunteers
- 640 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Yaws, Treponema Infection
Single-dose Azithromycin for the Treatment of Yaws
Yaws, an endemic treponematosis and as such a neglected tropical disease (NTD), is currently making a comeback in children in rural areas. Injectable long acting penicillin remains the drug of choice for the treatment of yaws.
- Conditions
- Yaws, Treponema Infection, Neglected Tropical Disease
- Trial name
- NCT01382004
- Testing
- Penicillin-G-benzathine, Azithromycin
- Where
- Papua New Guinea
- Volunteers
- 255 people
- Sponsor
- Lihir Medical Centre
Gonorrhea
Zoliflodacin in Uncomplicated Gonorrhoea
This trial is a multi-center, open label, randomized controlled, non-inferiority phase III trial evaluating the safety and efficacy of a 3 g oral dose of zoliflodacin compared to a combination of a single intra-muscular 500 mg…
- Trial name
- NCT03959527
- Testing
- zoliflodacin, ceftriaxone, azithromycin
- Where
- 17 sites in United States, Belgium and 3 more
- Volunteers
- 1,011 people
- Sponsor
- Global Antibiotics Research and Development Partnership
Pityriasis Lichenoides
Pityriasis Lichenoides Chronica, Role of Streptococcal Infection and Azithromycin
Primary outcome: The primary outcome at end of study (EOS) is to compare the therapeutic efficacy of Azithromycin in the treatment of pityriasis lichenoides chronica (PLC) with that of a well-documented line of therapy namely…
- Trial name
- NCT03831269
- Testing
- Azithromycin, nbUVB
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Severe Acute Malnutrition, HIV
An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM
Malnutrition underlies 45% of child deaths, and has far-reaching educational, economic and health consequences. Severe acute malnutrition (SAM) affects 17 million children globally and is the most life-threatening form of…
- Conditions
- Severe Acute Malnutrition, HIV, Comorbidities and Coexisting Conditions, Child Malnutrition
- Trial name
- Co-SAM (NCT05994742)
- Testing
- Rifampicin, Azithromycin, Isoniazid
- Where
- 9 sites in Kenya, Zambia and 1 more
- Volunteers
- 674 people
- Sponsor
- Queen Mary University of London
Undifferentiated Febrile Illness
Nepal Undifferentiated Febrile Illness Trial
The purpose of the study is to determine whether azithromycin or cotrimoxazole is the best empirical treatment for undifferentiated febrile illness in Nepal
- Trial name
- NUFIT (NCT02773407)
- Testing
- Azithromycin, Co-trimoxazole
- Where
- 2 sites in Nepal
- Volunteers
- 330 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Bronchopulmonary Dysplasia
Azithromycin in the Prevention of Lung Injury in Premature Newborn
The introduction of invasive mechanical ventilation in the treatment of preterm infants works as an adjuvant in the treatment of acute respiratory failure, which has resulted in significantly significant survival rates.
- Trial name
- NCT03485703
- Testing
- Azithromycin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre