Clinical trials: Cholecalciferol
Irritable Bowel Syndrome (IBS), Vitamin D Deficiency
Role of Vitamin D Supplementation in Children With Irritable Bowel Syndrome
This study was designed to determine whether vitamin D supplementation improved symptoms in children with irritable bowel syndrome, a condition associated with repeated abdominal pain and changes in bowel habits.
- Trial name
- NCT07914478
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aziz Bhatti Shaheed Teaching Hospital
Transient Hypercalciuria
Assessing the Impact of a Mode of Vitamin D Supplementation (Sequential Dose vs Daily Dose) on the Incidence of Hypercalciuria in Subjets Aged From 2 to 18 Years
Recommendations for vitamin D supplementation for subjets between 2 and 18 years offer strong sequential doses of vitamin D: 2 times 100 000 units in spaced winter period of 3 months.
- Trial name
- DonneDVit (NCT02975492)
- Testing
- Cholecalciferol sequential dose, Cholecalciferol daily dose
- Where
- 2 sites in France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Iron Deficiency Anemia
Effect of Vitamin D Supplementation Added to Iron Therapy in Children With Iron Deficiency Anemia
This randomized controlled trial will evaluate the effect of two vitamin D3 supplementation regimens, administered in addition to oral iron therapy, on hematological and iron status in children aged 6-60 months with confirmed…
- Trial name
- NCT07892170
- Testing
- Elemental iron, Vitamin D3 2000 IU/day, Vitamin D3 400 IU/day
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Crohn Disease
The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )
The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relapses) and the quality of life, including levels of physical activity, in children diagnosed Crohn's disease…
- Trial name
- ViDiPeC-2 (NCT03999580)
- Testing
- vitamin D3
- Where
- 7 sites in Canada
- Volunteers
- 55 people
- Sponsor
- Jantchou Prevost
Hypovitaminosis D
The Effectiveness of a Weight-dependent Algorithm for Dosing Vitamin D.
Vitamin D is essential for calcium absorption and bone growth, brain development, and immune system function. Vitamin D is produced by the body in response to natural sunlight.
- Trial name
- NCT07876843
- Testing
- Vitamin D3, Calcium, and Vitamin C
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Type 1 Diabetes Mellitus
A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd also known as retogatein compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous…
- Trial name
- DIAGNODE-3 (NCT05018585)
- Testing
- Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Colecalciferol 2000 IU
- Where
- 60 sites in United States, Czechia and 7 more
- Volunteers
- 321 people
- Sponsor
- Diamyd Medical AB
Vitamin D Deficiency
ViDES Trial (Vitamin D Extra Supplementation)
The objective of the study is to compare supplementation with vitamin D at 800 IU/day to usual care for the first 28 days after birth with respect to 25 (OH) vitamin D levels and indicators of likely or plausible effects of…
- Trial name
- NCT05459298
- Testing
- 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The University of Texas Health Science Center, Houston
Vitamin D Deficiency
Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight
The objective of the study is to compare supplementation with vitamin D at 800 IU/day to usual care for the first 28 days after birth with respect to 25 (OH) vitamin D levels and indicators of likely or plausible effects of…
- Trial name
- NCT05694689
- Testing
- 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Vitamin D Deficiency, Breast Milk Collection
Vitamin D Sulfates in Breastmilk
Infants The purpose of this study is to measure breastmilk's vitamin D sulfate nutritional value in infant's saliva and digesta (gut).
- Trial name
- NCT06203041
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Urinary Bladder, Overactive, Overactive Bladder
Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet
The purpose of this clinical trial is to investigate whether adding high-dose vitamin D (2,400 IU daily) to standard medical treatment (solifenacin combined with behavioral therapy) is more effective than standard treatment alone…
- Conditions
- Urinary Bladder, Overactive, Overactive Bladder, Urinary Incontinence, Urge
- Trial name
- NCT06201013
- Testing
- urotherapy, Solifenacin Succinate, Vitamin D3
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Enuresis
Efficacy and Safety of Vitamin D Supplementation Combined With Alarm Therapy in Treating Nocturnal Enuresis
This prospective, randomized, two-arm, parallel-design controlled clinical trial aims to determine whether high-dose vitamin D supplementation combined with alarm therapy improves outcomes in children with primary monosymptomatic…
- Trial name
- NCT06508333
- Testing
- alarm therapy, Vitamin D3
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Xing Liu
Rotaviral Gastroenteritis
Evaluation of the Role of Vitamin D in Reducing the Severity and Duration of Rotavirus Infection in Iraqi Children
The aim of this study is to evaluate the effect of vitamin D supplementation on the clinical outcomes including duration and severity of rotavirus-induced gastroenteritis in children that will be admitted to the hospital.
- Trial name
- NCT07167797
- Testing
- Vitamin D (Cholecalciferol ), Standard treatment for rotavirus
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad
Food Allergy
Can Vitamin D Supplementation in the First Year of Life Prevent Food Allergy in Infants? The VITALITY Trial: Parts 1&2
We report that Australia has the highest prevalence of Immunoglobulin(Ig)E-mediated food allergy in the world, with 10% of infants having challenge-proven food allergy in Melbourne.
- Trial name
- VITALITY (NCT02112734)
- Testing
- Vitamin D
- Where
- Australia
- Volunteers
- 2,739 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Corrosive Injury
Evaluation of the Role of N Acetyl Cysteine and Vitamin D in Improving Outcomes After Corrosive Ingestion
The goal of this clinical trial is to learn if N acetyl cysteine and vitaminD work to improve outcomes after corrosive ingestion in children.
- Trial name
- NCT07229456
- Testing
- N Acetyl Cysteine, Vitamin D (Cholecalciferol ), control group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Sickle Cell Disease, Anemia, Sickle Cell
Daily Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Anemia, Sickle Cell, Anemia, Hemolytic, Congenital, Respiratory Tract Diseases
- Trial name
- ViDAS-2 (NCT04170348)
- Testing
- Daily oral vitamin D3, 3,333 IU, Monthly oral vitamin D3, 100,000 IU
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Diabetes Mellitus, Type 1, Hypoglycemia
Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients
The investigator propose to test the safety and efficacy of a regimen that combines Omega-3 Fatty Acids and Vitamin D in a design that considers timing and duration of administration in relation to their effects and predicted…
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune
- Trial name
- POSEIDON (NCT03406897)
- Testing
- Cholecalciferol, Omega 3 fatty acid
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rodolfo Alejandro
Chronic Kidney Disease, Renal Transplantation
Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.
Vitamin D is not seen anymore only as a phosphocalcic and bone hormone, but also as having an effect on global health (anti-infective, anti-inflammatory, anti-tumour roles and cardiovascular protection).
- Conditions
- Chronic Kidney Disease, Renal Transplantation, Nephrotic Syndrome
- Trial name
- VITATOL (NCT02238418)
- Testing
- Cholecalciferol vial (100 000 UI)
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Hyperbilirubinemia
Effect of Vitamin-D as an Adjuvant to Phototherapy in Reduction of Indirect Serum Bilirubin
The study aimed at filling the gaps by evaluating the effectiveness of vitamin-D as an adjuvant to phototherapy in reduction of indirect serum bilirubin among neonates with exaggerated physiological hyperbilirubinemia.
- Trial name
- NCT07098234
- Testing
- Vitamin D3, Phototherapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Muhammad Aamir Latif
Depressive Symptoms
An Evaluation of the Effect of Vitamin D Supplementation on Depressive Symptoms Among Chinese Early Adolescents
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on depression in Chinese early adolescents with elevated depressive symptoms and vitamin D deficiency.
- Trial name
- NCT06247930
- Testing
- Vitamin D3, Mental health education
- Where
- 2 sites in China
- Volunteers
- 406 people
- Sponsor
- Anhui Medical University
Obesity, Childhood
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries.
- Trial name
- OBEVIDOS (NCT03516968)
- Testing
- Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os
- Where
- 4 sites in France
- Volunteers
- 68 people
- Sponsor
- Hospices Civils de Lyon