Clinical trials: Ibuprofen
Osteoarthritis, Hip, Arthroplasty, Replacement, Hip
Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone…
- Conditions
- Osteoarthritis, Hip, Arthroplasty, Replacement, Hip, Arthritis, Rheumatoid
- Trial name
- NCT00145730
- Testing
- Ibuprofen
- Volunteers
- 1,000 people
- Sponsor
- The George Institute
Hypospadias
Assessment of Postop Hypospadias Pain
One of the most common pediatric urology procedures is hypospadias repair, a surgery to correct curvature of the penis and move the urethral meatus into the glans.
- Trial name
- NCT04423107
- Testing
- Acetaminophen, Ibuprofen, Acetaminophen, Ibuprofen, Oxycodone
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oklahoma
Patent Ductus Arteriosus
Treatment of a PDA With Acetaminophen in Preterm Neonates: Exploring Various Indications
This study will evaluate the use of acetaminophen in preterm infants when a patent ductus arteriosus (PDA) is of concern. We will perform two simultaneous prospective observational studies over a 3 year period.
- Trial name
- NCT03289390
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Albany Medical College
Pain
Postoperative Effects of Chewing Gum, Ibuprofen and Acetaminophen on Pain After Initial Archwire Placement
The purpose of this study is to compare the efficacy of ibuprofen, acetaminophen, chewing gum in reducing orthodontic pain. This study include 81 patients to be classified into 4 groups of 19 each: ibuprofen (400 mg)…
- Trial name
- PECI (NCT03568721)
- Testing
- Ibuprofen, Acetaminophen, Chewing gum
- Where
- Brazil
- Volunteers
- 81 people
- Sponsor
- Rio de Janeiro State University
Hand, Foot and Mouth Disease
A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
The aim of this study is to evaluate the effectiveness and safety of Xiyanping Injection for mild type of hand, foot, and mouth disease.
- Trial name
- NCT01182025
- Testing
- Western therapy, Xiyanping Injection, Xiyanping Injection with western medicine
- Where
- 5 sites in China
- Volunteers
- 360 people
- Sponsor
- The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Mild Ankle Sprain
Mild Ankle Sprain Treatment: Functional Bandaging vs. no Immobilization
Ankle sprains represent a prevalent pathology among the pediatric population that can result in residual effects when treated incorrectly.
- Trial name
- PED_HUIL1223 (NCT06189625)
- Testing
- Control, Functional bandage
- Where
- Spain
- Volunteers
- 113 people
- Sponsor
- Hospital Universitario Infanta Leonor
Otitis Media
The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income Population
Importance: Ear pain is a frequent reason for pediatric visits. Objective: To determine if a program of anticipatory guidance counseling for ear pain at the 12-15 month routine preventive care visit in a predominantly low income…
- Trial name
- NCT02616458
- Testing
- ear pain counseling, language power counseling
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- University of Colorado, Denver
Patent Ductus Arteriosus, Infant, Premature
Ibuprofen vs Expectant Management for hsPDA in Preterm Infants: Retrospective Cohort
This retrospective cohort study compares ibuprofen treatment versus expectant management for hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants.
- Trial name
- IMPACT-PDA (NCT07533721)
- Testing
- Ibuprofen
- Where
- China
- Volunteers
- 541 people
- Sponsor
- Shengjing Hospital
Pediatric Anesthesia, Premedication
Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery
This prospective, three-arm study aims to evaluate the effects of different oral premedication regimens on venipuncture tolerance in pediatric patients undergoing ambulatory surgery.
- Trial name
- NCT07410078
- Testing
- Oral Midazolam Premedication, Oral Midazolam plus Ibuprofen Premedication, Oral Midazolam plus Ketamine Premedication
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Retinopathy of Prematurity, Pain Management
Pain Management During Screening for Retinopathy of Prematurity
Abstract Background: Screening examinations for retinopathy of prematurity (ROP) is critical to reduce ROP-related vision loss, however, the procedure is painful and uncomfortable, and topical anesthetics do not completely…
- Trial name
- NCT04767178
- Testing
- Ibuprofen (Sanofi, Istanbul, Turkey), Paracetamol (GlaxoSmithKline, Istanbul, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul Medeniyet University
Patent Ductus Arteriosus, Extreme Prematurity
Canadian National PDA Treatment Study
Patent ductus arteriosus (PDA) is the most common cardiovascular problem that develops in preterm infants. Persistent PDA may result in higher rates of death, chronic lung disease (CLD), pulmonary hemorrhage, necrotizing…
- Trial name
- CANRxPDA (NCT04347720)
- Testing
- Indomethacin, Ibuprofen, Acetaminophen
- Where
- 22 sites in Canada
- Volunteers
- 1,663 people
- Sponsor
- IWK Health Centre
Juvenile Idiopathic Arthritis
Open-label Safety and Pharmacokinetic Study of DUEXIS® (Ibuprofen and Famotidine) Tablets in Juvenile Idiopathic Arthritis
The primary objective of this Phase 4, multi-center, open-label study is to evaluate the safety and tolerability of DUEXIS in Juvenile Idiopathic Arthritis (JIA) patients aged 10 years to 16 years, 11 months, treated up to 24…
- Trial name
- NCT01563185
- Testing
- 800 mg ibuprofen/26.6 mg famotidine
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Amgen
Aphthous Stomatitis
Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis
The intention of the study is to study the effects of Ibuprofen, Diphenhydramine and Aluminium MgS in decreasing the signs of recurrent aphthous stomatitis (RAS)
- Trial name
- NCT01293968
- Testing
- Ibuprofen, Diphenhydramine and Aluminium MgS, Diphenhydramine and Aluminium MgS
- Where
- 2 sites in Iran
- Volunteers
- 37 people
- Sponsor
- Qazvin University Of Medical Sciences
Reversible Pulpitis, Ibuprofen
Pain Management in Teeth With Reversible Pulpitis
Effective intraoperative pain management is vital in paediatric dentistry, especially during vital pulp therapy (VPT) for reversible pulpitis.
- Trial name
- NCT07114198
- Testing
- Ibuprofen 10 mg/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Inonu University
Back Pain, Scoliosis
Back Pain and Spinal Manipulation in Adolescent Scoliosis
Adolescent idiopathic scoliosis (AIS) affects 2 - 3% of children and adolescents older than 10 years and is of unknown cause. It was initially thought that occurrences of back pain (BP) were similar to the one encounter in…
- Trial name
- NCT02609009
- Testing
- Spinal Manipulation Therapy, Usual Medical Care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Patent Ductus Arteriosus After Premature Birth
Paracetamol Versus Ibuprofen in Premature Infants With Hemodynamically Significant Patent Ductus Arteriosus
Multicentric, double-blind clinical trial, which will evaluate the efficacy of iv paracetamol versus standard treatment with ibuprofen in the closure of patent ductus arteriosus in the preterm newborn.
- Trial name
- IBUPAR (NCT04037514)
- Testing
- Paracetamol, Ibuprofen
- Where
- 4 sites in Spain
- Volunteers
- 133 people
- Sponsor
- Máximo Vento Torres
Pain
Pain and Medical Abortion Among Teenaged Women Compared to Adult Women
In this two-parted study the need and sufficiency of analgesics and experienced pain is compared between teen-aged and adult women undergoing medical termination of pregnancy (MToP)in early pregnancy (under 9weeks of gestation).
- Trial name
- NCT02678897
- Testing
- Oxynorm on-demand, Oxynorm via PCA
- Where
- 2 sites in Finland
- Volunteers
- 242 people
- Sponsor
- Helsinki University Central Hospital
Fever
Adding a Second Drug for Febrile Children Treated With Acetaminophen
Fever is one of the most common symptoms in pediatrics and one of the most common reasons for visits in pediatricians' office and pediatric emergency departments. Many parents consider fever to be the most terrifying symptom.
- Trial name
- NCT00389272
- Testing
- Ibuprofen, acetaminophen
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Hypertension
NSAID Use in Postpartum Hypertensive Women
Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period.
- Trial name
- NCT02902172
- Testing
- Acetaminophen, NSAID
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Patent Ductus Arteriosus
Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus
The purpose of this pilot trial is to study efficacy and safety of simultaneous intravenous (iv) ibuprofen/indomethacin and paracetamol medications in the closure of patent ductus arteriosus (PDA) in preterm infants.
- Trial name
- PAI (NCT03648437)
- Testing
- Paracetamol 10Mg/mL, 0.45% Sodium Chloride, Ibuprofen
- Where
- 4 sites in Finland
- Volunteers
- 22 people
- Sponsor
- University of Oulu