Clinical trials: Omeprazole
Henoch-Schönlein Purpura
Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura
IgA vasculitis is relatively common in children,especially in Asian countries. Abdominal manifestation could be severe, including bleeding, pancreatitis,appendicitis and intestinal intussusception.
- Trial name
- NCT03647852
- Testing
- Methylprednisolone, IVIG, other basic supportive treatment
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- Children's Hospital of Fudan University
H Pylori
Comparison of Omeprazole vs Vonoprazon in Treatment of H Pylori Infection
Current studies have primarily focused on comparing the advantages and disadvantages of P-CAB and PPI drugs, with little comparison between different P-CAB drugs or between regimens with varying drug combinations and treatment…
- Trial name
- NCT07040839
- Testing
- Clarithromycin 500 mg, Amoxicillin 1 g, Omeprazole 40 mg
- Where
- Pakistan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Clostridium Difficile Infection
Effect of Acid Suppression Medication on Pediatric Microbiome
The colonic microbiome is essential in health and disease, and is highly dynamic during the first several years of life. Proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) are widely used in children, but…
- Trial name
- NCT02016820
- Testing
- Omeprazole (suspension), Lifestyle Modification
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
Functional Gastrointestinal Disorders
Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders
Safety and efficacy of FMT in Pediatric Functional Gastrointestinal Disorders
- Trial name
- FGIDs (NCT05753774)
- Testing
- FMT, Conventional drugs
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Biao Zou
Diffuse Large B-Cell Lymphoma (DLBCL), Primary Mediastinal Large B-cell Lymphoma
Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Previously Untreated Aggressive Non-Hodgkin's Lymphoma
5-Drug Combination Chemotherapy with Hematologic Toxicity Attenuation. Etoposide phosphate, prednisone, vincristine sulfate (Oncovin), cyclophosphamide, and doxorubicin hydrochloride (hydroxydaunorubicin)(EPOCH): Etoposide…
- Conditions
- Diffuse Large B-Cell Lymphoma (DLBCL), Primary Mediastinal Large B-cell Lymphoma, Burkitt Lymphoma, Anaplastic Large-Cell Lymphoma
- Trial name
- NCT00001337
- Testing
- Etoposide, Rituximab, Prednisone
- Where
- 5 sites in United States
- Volunteers
- 348 people
- Sponsor
- National Cancer Institute (NCI)
Helicobacter Pylori Infection
ADDITION OF BISMUTH TO THE STANDARD TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION
H pylori is an important cause of chronic gastritis and other complications. There is a decline in eradication rate for H pylori owing to multiple factors including drug resistance.
- Trial name
- NCT03968302
- Testing
- ARM A Triple therapy for helicobacter pylori, ARM B Quadruple therapy for helicobacter pylori
- Where
- Pakistan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
MALT Lymphoma
Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of MALToma
To evaluate the therapeutic effectiveness of H. pylori eradication in stage IE \& IIE-1 primary low-grade B cell lymphoma of MALT of the stomach
- Trial name
- NCT00201422
- Testing
- Omeprazole, Amoxicillin, Clarithromycin
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Health Research Institutes, Taiwan
Prostatic Neoplasm
The Effects of Method of Anaesthesia on the Safety and Effectiveness of Radical Retropubic Prostatectomy
Prostate cancer is one of the most commonly diagnosed neoplasm in men worldwide. The gold standard of therapy is radical prostatectomy, a wide surgical excision of the neoplasm and can be performed either open, laparoscopic or…
- Trial name
- NCT05566405
- Testing
- General Anaesthesia, Combined (Epidural and Spinal) Anaesthesia, Open Retropubic Radical Prostatectomy
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Sismanoglio General Hospital
Omeprazole
Evaluation of the Prophylactic Use of Omeprazole in Patients Admitted to the State Hospital of Américo Brasiliense
Introduction. The prevalence of the use of drugs that act on the gastric system has increased in the population. Omeprazole is an inhibitor of the protons pump and has a widespread use, mainly as a prophylactic to prevent reflux…
- Trial name
- NCT02278432
- Volunteers
- 427 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Barrett Esophagus, Gastroesophageal Reflux
Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus
The purpose of this research study is to assess how safe, effective (how well it works), and tolerable (to put up with) the drug Zegerid is in reducing reflux episodes in patients who have both gastroesophageal reflux disease…
- Trial name
- NCT01129778
- Testing
- Zegerid (proton pump inhibitor), Bravo pH monitoring
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Stanford University
Peptic Ulcer
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
To evaluate if intravenous PPI infusion, when administered prior to endoscopy, hastens resolution of bleeding stigmata and thereby facilitates endoscopic examinations and reduces the need for endoscopic treatment.
- Trial name
- NCT00164866
- Testing
- Omeprazole
- Where
- China
- Volunteers
- 638 people
- Sponsor
- Chinese University of Hong Kong
Peptic Ulcer
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer
Proton Pump Inhibitors (PPI) can prevent the recurrence of peptic ulcer in clopidogrel users.
- Trial name
- NCT01138969
- Testing
- esomeprazole
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Gastreoesophageal Reflux Disease
Pharmacokinetics of Enteral Omeprazole Suspension in Patients With Cerebral Palsy and Mental Retardation
Gastroesophageal reflux disease and reflux-esophagitis are a major chronic problem in most children with cerebral palsy and mental retardation.
- Trial name
- NCT00426595
- Testing
- Administration of omeprazole suspension, omeprazole administered as a multi-unit-pellet system
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- University Hospital, Ghent
Esophageal Atresia, Esophagitis
Management of Esophagitis Following Repair of Esophageal Atresia
The goal of this study is to prospectively evaluate the impact of antacid therapy on esophagitis in children with repaired esophageal atresia.
- Trial name
- NCT03619408
- Testing
- Antacids
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital