Clinical trials: Propranolol, open to volunteers
Infantile Hemangioma (IH)
Abrupt Discontinuation Versus Gradual Tapering of Propranolol in Infantile Hemangioma
Infantile hemangioma is the most common benign vascular tumor in infancy. Oral propranolol is the first-line systemic treatment for infantile hemangiomas requiring therapy.
- Trial name
- PROIHSTOP (NCT07665177)
- Testing
- Abrupt Discontinuation of Propranolol, Gradual Tapering of Propranolol
- Where
- China
- Volunteers
- 110 people
- Sponsor
- West China Hospital
Migraine Disorders
Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine
This randomized controlled trial evaluated whether adding melatonin to propranolol provided better prevention of migraine in children than propranolol alone.
- Trial name
- NCT07743255
- Testing
- Melatonin, Propranolol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Hemangioma
A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma.
- Trial name
- NCT01873131
- Testing
- topical timolol maleate, Pulsed dye laser
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Kaposi Sarcoma
A Study of Propranolol to Treat Kaposi Sarcoma
A clinical study of propranolol for the treatment of Kaposi Sarcoma in children and adults. This study will be an open-label single armed treatment trial that will test the effectiveness and the safety of treating Kaposi Sarcoma…
- Trial name
- NCT05797662
- Testing
- Propranolol
- Where
- 6 sites in Argentina, Brazil and 3 more
- Volunteers
- 25 people
- Sponsor
- AIDS Malignancy Consortium
Infantile Hemangioma
Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma
The main objective of this study was to determine the efficacy of different doses of propranolol in the treatment of ulcerattion infantile hemangioma (IH).
- Trial name
- NCT06798363
- Testing
- propranolol
- Where
- 3 sites in China
- Volunteers
- 32 people
- Sponsor
- West China Hospital
Long QT Syndrome, Hypoglycemia
Frequency of Hypoglycemia in Children With Beta-blocker Treated Long QT-syndrome
The goal of this observational study is to investigate the frequency and characteristics of hypoglycemic episodes in children with long QT syndrome (LQTS) and beta-blocker treatment, specifically those receiving propranolol…
- Trial name
- LQThypo (NCT07233421)
- Testing
- Continuous Glucose Monitoring
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Retinopathy of Prematurity
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity
Extremely premature infants are at risk of developing a potentially blinding eye disease, called retinopathy of prematurity (ROP).
- Trial name
- RoProp (NCT03083431)
- Testing
- Propranolol
- Where
- 3 sites in Germany, Switzerland and 1 more
- Volunteers
- 276 people
- Sponsor
- University of Zurich
Migraine
Comparative Efficacy of Flunarizine and Propanolol in Pediatric Migraine
Flunarizine and propranolol have demonstrated efficacy in reducing migraine frequency across age groups, though evidence in pediatric populations remains limited and inconsistent.
- Trial name
- NCT07354126
- Testing
- Flunarizine, Propranolol
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Muhammad Aamir Latif
Tetralogy of Fallot, Double Outlet Right Ventricle
Beta-blocker Administration for Cardiomyocyte Division
Heart failure is a common long-term complication in patients with congenital heart disease (CHD). Medical treatments to promote regeneration of new healthy heart muscle cells have the potential to provide new heart failure…
- Trial name
- NCT04713657
- Testing
- N-thymidine, Urine Collection, Echocardiogram
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
PTSD
Treatment of Pediatric Post-traumatic Stress Disorder With Memory Reactivation Under the Influence of Propranolol
By age 18, roughly 8% of traumatized youth have met criteria for a diagnosis of PTSD, with numbers rising up to 40% in cases of sexual abuse and assault.
- Trial name
- PPP (NCT04985344)
- Testing
- Propranolol Oral Product, memory reactivation
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Toulouse
Propranolol, Labour Induction
Effects of Oral Propranolol on Induction-Delivery Interval During Induction of Labour With Oxytocin
Prolonged pregnancy could lead to perinatal and maternal complications. Oxytocin has been wildly used for induction of labour, but prolonged labour continued to occur with its attendant sequelae.
- Trial name
- NCT06960850
- Testing
- Propranolol
- Where
- Nigeria
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Intracerebral Hemorrhage, Stroke-Associated Pneumonia (SAP)
An Open-Label, Dose-Escalation Study on the Safety, Tolerability and Preliminary Efficacy for Preventing SAP by Intravenous Pump-Delivered Propranolol in Patients With ICH
This is an open-label, dose-escalation study on the safety, tolerability and preliminary efficacy for preventing stroke-associated pneumonia of propranolol in patients with intracerebral hemorrhage.
- Trial name
- PROCHASE-DoE (NCT07528235)
- Testing
- Intravenous Pump-Delivered Propranolol
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tang-Du Hospital