Clinical trials: sponsored by Aarhus University Hospital
Persistent Physical Symptoms (PPS), Bodily Distress Syndrome
My Symptoms Young - a New Internet-based Programme for Young People With Persistent Physical Symptoms in Primary Care: Exploration of Effect and Health Literacy Characteristics Among Users
The research programme is an ambitious effort aiming to improve overall functioning and quality of life for young people with bodily distress.
- Conditions
- Persistent Physical Symptoms (PPS), Bodily Distress Syndrome, Health Literacy, eHealth Literacy
- Trial name
- NCT07912515
- Testing
- My Symptoms Young - an internet-based self-help programme for young people with persistent physical symptoms
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Aarhus University Hospital
Pediatric Cancer, Cognitive Dysfunction
Engaging Parents in Neuropsychological Rehabilitation for Childhood Cancer Survivors: The ImPACT Program - A Pilot Study
The aim of the present pilot study is to evaluate the feasibility, acceptability, and preliminary efficacy of a novel, context-sensitive neuropsychological rehabilitation intervention for childhood cancer survivors and their…
- Trial name
- NCT05483166
- Testing
- ImPACT
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aarhus University Hospital
Lung Diseases
Investigating Novel Strategies in Pediatric Immune Responses and Microbiome Environment: Comprehensive Lung Disease Investigation in Children.
The INSPIRE CHILD-study is a clinical research project focused on understanding lung diseases in children. The study aims to explore how the presence of certain bacteria, immune responses, and inflammatory markers in the lungs…
- Trial name
- INSPIRE CHILD (NCT06746077)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aarhus University Hospital
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Medial Patellofemoral Dislocation, Medial Patellofemoral Ligament Reconstruction
Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study
The purpose of this project is to investigate the treatment outcome after MPFL reconstruction in children as a treatment for chronic patellar instability, where the superficial part of the quadriceps tendon is fixed to the femur…
- Trial name
- MPFL (NCT06257836)
- Testing
- MPFL-reconstruction
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 1
INfluenza VaccInation To Mitigate typE 1 Diabetes
In a multicenter, prospective, randomized, controlled clinical trial to compare influenza vaccination and placebo in sustaining β cell function in early type 1 diabetes mellitus.
- Trial name
- INVITED (NCT05585983)
- Testing
- Vaxigrip Tetra Sanofi Pasteur Europe
- Where
- 10 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Obsessive Compulsive Behavior
Digital OC Training in Children and Adolescents
The project is an interventional trial that compares digital training programs with varying levels of therapeutic contact. All participating children and adolescents will receive a digital training program following a thorough…
- Trial name
- DOT-Y (NCT07864675)
- Testing
- Digital behavioral training
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital
Acute Lymphoblastic Leukemia
Establishment of a Phamacokinetik Model for Erwinase Pharmacokinetiks: The Aim of This Sub Study is to Optimize Target Trough Attainment While Minimizing High Exposures That Impose Increased Risk of Side Effects Such as Hyperammonemia
The aim of this study is to optimize target trough attainment while minimizing high exposures that impose increased risk of side effects such as hyperammonemia.
- Trial name
- NCT07499349
- Testing
- Erwinase PK-model for children and young adults with ALL
- Where
- Denmark
- Volunteers
- 475 people
- Sponsor
- Aarhus University Hospital
Acute Lymphoblastic Leukaemia - Category
UNDERSTANDING THE T-CELL AND B-CELL RECEPTOR REPERTOIRE IN CHILDREN AND YOUNG ADULTS WITH ANTI-DRUG ANTIBODIES AGAINST PEG ASPARAGINASE
The aim of this sub study is to identify biomarkers in children and young adults with Acute Lymphoblastic Leukemia with hypersensitivity to PEG-asparaginase.
- Trial name
- NCT07499336
- Testing
- Hypersensitivity reaction to asparaginase
- Volunteers
- 45 people
- Sponsor
- Aarhus University Hospital
Tuberculosis (TB), Tuberculosis Infection, Latent
Burden of Tuberculosis Among Pregnant and Postpartum Women in Guinea-Bissau
This study aims to address critical diagnostic and data gaps in tuberculosis (TB) care among pregnant and postpartum women in Guinea-Bissau, a high-burden, resource-limited setting.
- Conditions
- Tuberculosis (TB), Tuberculosis Infection, Latent, Pregnancy, Tuberculosis Diagnosis
- Trial name
- TIPP (NCT07419568)
- Testing
- Enhanced protocol
- Where
- Guinea-Bissau
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Developmental Dysplasia of the Hip
Reliability of Ultrasound Metrics Used in Hip Dysplasia Diagnostics - a Prospective Study
Several measurements are used to evaluate hip dysplasia in hip ultrasound of children. Despite having being used since the 1980s, reliability studies have failed to find acceptable reliaiblity values for the gold standard…
- Trial name
- NCT06233487
- Testing
- Repeat hip ultrasound measurements
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Arthritis, Juvenile, Arthritis, Juvenile Idiopathic
Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric Setting
The proposed study aims to evaluate the effectiveness of hypnotherapy as a non-pharmacological intervention for managing pain and anxiety during needle-related medical procedures in children aged 5 to 17 years.
- Conditions
- Arthritis, Juvenile, Arthritis, Juvenile Idiopathic, Lupus Erythematosus, Systemic, Dermatomyositis, Juvenile
- Trial name
- NCT07349667
- Testing
- Hypnotherapy
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease
Nordic Bifurcation Study. How to Use Drug Eluting Stents (DES) in Bifurcation Lesions?
How to use drug eluting stents (DES) in bifurcation lesions. A strategy of routine stenting of both main vessel and side branch versus a strategy of routine main vessel stenting and optional treatment of side branch.
- Trial name
- BIFI (NCT00376571)
- Testing
- Percutaneous coronary intervention
- Where
- Denmark
- Volunteers
- 413 people
- Sponsor
- Aarhus University Hospital Skejby
Significant Coronary Artery Disease
Coronary Hybrid Revascularisation Study
The purpose of the registry is to assess results of combined operative and catheter based (hybrid procedure) treatment of patients with significant coronary artery disease using essential clinical and angiographic parameters.
- Trial name
- NCT01496664
- Testing
- Combined CABG and PCI
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease
Nordic Bifurcation Stent Technique Study (BIF II)
This is a study of crush- or culotte stenting of bifurcation lesions using drug eluting stents. This is a randomized Nordic multicenter study including 400 patients with angina pectoris with clinical angiographic follow-up.
- Trial name
- BIF II (NCT00292305)
- Testing
- Percutaneous coronary intervention
- Where
- Denmark
- Volunteers
- 425 people
- Sponsor
- Aarhus University Hospital Skejby
Sleep Problems, Insomnia
Sleep and Blankets
Purpose The primary aim of this research project is to evaluate whether a special blanket is an effective intervention for improving sleep among young people aged 16-24 with sleep disturbances.
- Trial name
- SWAN (NCT07181577)
- Testing
- Special blanket, Different special blanket
- Where
- Denmark
- Volunteers
- 672 people
- Sponsor
- Aarhus University Hospital
Tuberculosis
Increased Tuberculosis Case Detection - DiOpTB
As estimated by the WHO 10.6 million new Tuberculosis (TB) cases were identified in 2022- while more than three million went undetected and untreated.
- Trial name
- DiOpTB (NCT06437184)
- Testing
- ODP
- Where
- 2 sites in Ethiopia, Guinea-Bissau
- Volunteers
- 1,584 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Rupture
Comparison of Different Anterior Cruciate Ligament Surgery Techniques in Skeletally Immature Patients.
This cohort study compares to groups of patients with reconstruction of anterior cruciate ligament (ACL). Patients in group 1 had ACL-reconstruction in the years 2001-2010 with a transphyseal drilling technique.
- Trial name
- NCT04644497
- Testing
- ACL-reconstruction
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Patella Subluxation, Patellofemoral Pain Syndrome
Translation, Cross-cultural Validity and Reliability of a Danish Version of the Anterior Knee Pain Scale
The Anterior Knee Pain Scale (Kujala) is a questionnaire designed to assess adults with patellofemoral disorders and is widely used in both anterior knee pain and patellar dislocation patients.The questionnaire is a…
- Trial name
- Kujala-DK (NCT06257862)
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Aarhus University Hospital
Patella Dysplasia
Validity and Reliability of a Danish Version of the Banff Patella Instability Instrument (BPII 2.0-DK)
The Banff Patella Instability Instrument (BPII 2.0) is a disease-specific quality of life questionnaire designed to assess adults with patellar dislocations.
- Trial name
- NCT06257849
- Testing
- BPII 2.0
- Where
- 2 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- Aarhus University Hospital