Clinical trials: sponsored by Odense University Hospital
Respiratory Tract Infections (RTI), Lung Ultrasound
Ultrasound Findings in a Pediatric Population
The purpose of this study is to investigate whether focused ultrasound of the chest can be used in a practical way in children with respiratory symptoms.
- Trial name
- NCT07919613
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Odense University Hospital
Brain Tumor, Pediatric, Cancer-related Fatigue
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Cancer-related fatigue is a common and debilitating late effect in pediatric brain tumor survivors. Currently, evidence-based recommendations to ameliorate this condition are lacking.
- Conditions
- Brain Tumor, Pediatric, Cancer-related Fatigue, Methylphenidate
- Trial name
- EMBRAIN (NCT06905587)
- Testing
- Methylphenidate (MPH)
- Where
- 4 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Milk Allergy
Performance of the Basophil Activation Test in the Diagnosis of IgE-mediated Cow's Milk Allergy in Infants and Evaluation of Hydrolysate Allergenicity.
The goal of this clinical trial is to investigate if the basophil activation test (BAT) represents a safer, faster, and more cost-effective diagnostic modality than the state-of-the art diagnostic work-up (specifik IgE and oral…
- Trial name
- MilkBAT (NCT07900594)
- Testing
- Basophil activation test, quality of life questionnaire
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Food Allergy in Children
Immunotherapy for Curing Toddlers With Severe Food Allergy - a Paradigm Shift From Passive to Active Treatment With Multi-allergen Oral Immunotherapy
The aim is to study whether a multiallergen oral immunotherapy (OIT) strategy with slow up-dosing and low treatment dose against food allergy in young children (0.5-3 years) is safe and effective, a method to cure food allergy…
- Trial name
- INFO-DK (NCT07899359)
- Testing
- OIT multiallergen powder
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Multiple Myeloma in Relapse
Self-administered Subcutaneous Daratumumab in Patients With Multiple Myeloma
The main goal in this open label, phase four, prospective, non-randomized, sponsor-initiated multicenter feasibility study is to evaluate the feasibility and safety of self-administration of subcutaneously (SC) daratumumab in the…
- Trial name
- SCILLA (NCT07191379)
- Testing
- The study intervention is self-administration of SC daratumumab by the patient, thereby changing the administration from an outpatient setting to a home setting.
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Allergy in Children
Long Term Effect of AIT in Children
The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or…
- Trial name
- NCT06421415
- Testing
- Allergen Immunotherapy Extract
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Lung Disease Chronic
Severe Lung Disease in Childhood
Only little information exists about the long term consequences of having severe lung disease in childhood. The patient population is heterogenous and the prognostic markers are few.
- Trial name
- NCT06455800
- Testing
- lung function measurements
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Odense University Hospital
Medical Education in Thoracic Ultrasound
Evidence Based Education in Thoracic Ultrasound
The goal of this cluster randomized controlled trial is to evaluate if a web-based thoracic ultrasound (TUS) training program can effectively educate users non-inferiorly to traditional classroom teaching in physicians and…
- Trial name
- NCT07846228
- Testing
- Web-based Thoracic Ultrasound Training, Class based Thoracic Ultrasound Training
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Congenital Hyperinsulinism (CHI)
Umbilical Cord Glucose
Congenital hyperinsulinism (HI) causes persistent neonatal hypoglycemia that, if untreated, can lead to neurodevelopmental impairments (NDI) such as cognitive delays, cerebral palsy, epilepsy, and blindness.
- Trial name
- Save The Brain (NCT07795047)
- Testing
- For the screening, the interventions will be glucose measurements (and possibly G-BOBH), while follow-up assessments will include Bayley testing, EEG, and MRI.
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease
The DANish COronary DEcalcification (DANCODE) Trial
1. Abstract Introduction Coronary artery calcification (CAC) and especially progression in CAC is a strong predictor of acute myocardial infarction and cardiovascular mortality.
- Trial name
- DANCODE (NCT05500443)
- Testing
- Vitamin K2 (Menaquinone-7)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Odense University Hospital
Hysteroscopy, Assessment Methods in Medical Training
Assessment of Hysteroscopy Skills With a New Assessment Tool
Objective To investigate validity of the hysteroscopy assessment tool (HYSAT) for assessment of competence in a clinical environment.
- Conditions
- Hysteroscopy, Assessment Methods in Medical Training, Medical Education, Diagnostic Hysteroscopy
- Trial name
- NCT07672288
- Testing
- Evaluation score based on assessment tool
- Where
- 2 sites in Canada, Denmark
- Volunteers
- 24 people
- Sponsor
- Odense University Hospital
Physical Disability, Physical Activity
Frame Running for Exercise and Participation for Children and Young People With Physical Disabilities
The goal of this quasi-experimental single-arm trial is to evaluate whether a structured Frame Running training program can improve functional ability, participation, and quality of life in children and young people with physical…
- Conditions
- Physical Disability, Physical Activity, Physical Function, Quality of Life
- Trial name
- FRAME-EX (NCT07543614)
- Testing
- Frame Running Training
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Acute Respiratory Disease
Positioning of Children With Acute Respiratory Insufficiency
Acute respiratory insufficiency is one of the most common causes of hospitalization and death among young children. It often affects small children who, due to infections with RSV (respiratory syncytial virus), other cold…
- Trial name
- NCT07170085
- Testing
- positioning
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
ED, Adipose Derived Stem Cells
Can Adipose Derived Regenrative Cells be Used for Treating Erectile Dysfunction After Radical Prostatectomy
The goal of this study was to investigate if adipose derived regenerative cells can be used as a treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT07355530
- Testing
- Adipose-Derived Regenerative Cells
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Gastroesophageal Reflux, Infant, Newborn, Diseases
Treatment of Gastroesophageal Reflux Disease in Infants
Gastroesophageal reflux disease in infants is not fully understood. Infants are prescribed medical treatments that may not be effective or that contribute to adverse side effects and lead to concerns and expenses for the parents…
- Trial name
- NCT06255886
- Testing
- Protein pump inhibitor., Mother or infant diet
- Where
- 3 sites in Denmark
- Volunteers
- 96 people
- Sponsor
- Odense University Hospital
Obesity, Life Style, Healthy
LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers
The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study. The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and…
- Conditions
- Obesity, Life Style, Healthy, Follow-up, Gestational Weight Gain
- Trial name
- NCT05774652
- Testing
- Lifestyle intervention Dietary advise and/or advise on physical activity
- Where
- Denmark
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Osteoporosis in Post-menopausal Women
A Clinical Study on the Effect of Discontinuing Alendronate in Postmenopausal Women With Osteoporosis After a Treatment Period Without Fractures
The goal of this clinical trial is to study the effects of discontinuation of Alendronate treatment for three years. The participants are postmenopausal women with osteoporosis, who have had a treatment period without fractures.
- Trial name
- ALEXIS (NCT06864130)
- Testing
- Alendronate 70mg weekly
- Where
- 7 sites in Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Periprosthetic Knee Infection
Outcome After Revisions of Infected Knee Arthroplasties
A prospective multicenter cohort study on all types of revision knee arthroplasty procedures performed due to infection.
- Trial name
- RIKA (NCT04427943)
- Testing
- revision surgery
- Where
- 8 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Periprosthetic Knee Infection
One-stage Versus Two-stage Revision of the Infected Knee Arthroplasty
This study investigates functional outcome and safety after one-stage versus two-stage revision of the infected knee arthroplasty.
- Trial name
- NCT03435679
- Testing
- one-stage, two-stage
- Where
- 9 sites in Denmark
- Volunteers
- 97 people
- Sponsor
- Odense University Hospital
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital