Clinical trials: sponsored by Shengjing Hospital
Spinal Cord Injuries (SCI)
The Predictive Value of Lower Extremity Hypertonia on Neurogenic Detrusor Overactivity After Spinal Cord Injury
The goal of this observational study is to evaluate whether increased lower extremity muscle tone can serve as an independent predictor of neurogenic detrusor overactivity (NDO) in adult patients (aged 18-80 years) with upper…
- Trial name
- NCT07695662
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Brain Neoplasms
MR Elastography in Intracranial Lesions: Feasibility & Accuracy
Brain tumors, despite their relatively low incidence among cancers, are associated with high morbidity and mortality due to the brain's complexity.
- Trial name
- NCT06916715
- Where
- China
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Patent Ductus Arteriosus, Infant, Premature
Ibuprofen vs Expectant Management for hsPDA in Preterm Infants: Retrospective Cohort
This retrospective cohort study compares ibuprofen treatment versus expectant management for hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants.
- Trial name
- IMPACT-PDA (NCT07533721)
- Testing
- Ibuprofen
- Where
- China
- Volunteers
- 541 people
- Sponsor
- Shengjing Hospital
Meningitis
Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis Subdural Lesions: Superior Efficacy, Critical Impact of Surgical Timing, and Pathogenic Bacteria as Risk Factors for Progression
Globally, approximately 750,000 cases of infantile meningitis occur annually[1]. Clinical data show infantile postmeningitis subdural fluid collection (IPSFC) is the most common complication of infantile bacterial meningitis…
- Trial name
- NCT07320599
- Testing
- Endoscopic Subdural Fluid Collection Evacuation & Ommaya Reservoir Implantation
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Hyperthyroidism
A Clinical Study of Hyperthyroidism in Children
This study intends to conduct a retrospective and prospective study on children with hyperthyroidism, and it is a non-intervention study to collect information on diagnosis and treatment and long-term follow-up of children with…
- Trial name
- NCT06570967
- Testing
- Methimazole(MMI)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shengjing Hospital
Fecal Microbiota Transplantation, Constipation - Functional
RCE With FMT in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood gastrointestinal disease, affecting an estimated 20% of the global children.The treatment strategies consist of diet control, behavioral intervention and oral and sometimes…
- Trial name
- NCT05035784
- Testing
- Fecal supernatant
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Constipation, Chinese Herbal Medicine
Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood gastrointestinal disease,affecting an estimated 20% of the global children.The treatment strategies consist of diet control,behavioural intervention and oral and sometimes…
- Trial name
- NCT03186079
- Testing
- Xiaojidaozhi Decoction, Fiberform, Toilet training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shengjing Hospital
Constipation, Childhood ALL
PTNS and PFR in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood, affecting an estimated 20% of children globally. At present, the treatment of children's constipation is full of challenges, and treatment methods are diverse.
- Conditions
- Constipation, Childhood ALL, Pelvic Floor Disorders
- Trial name
- NCT05059756
- Testing
- PTNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Recruiting
VTE Risk Prevention System Based on Big Data Analysis and Multimodule System
Venous thromboembolism (VTE) is one of the most common complications in perioperative period and the most common cause of postoperative death. VTE includes deep vein thrombosis (DVT) and acute pulmonary thromboembolism (PTE).
- Trial name
- NCT05969951
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Shengjing Hospital
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage
Ultrasound Measurements of Circular Cartilage Transverse Diameter
This study with children under 1 age of elective surgery as the research subjects, according to the cross diameter, compared with the traditional method of empirical catheter model, analyze the success rate, completion time of…
- Conditions
- Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage, Endotracheal Intubation, Children
- Trial name
- NCT05273294
- Testing
- Portable color Doppler ultrasound system
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shengjing Hospital
Anemia, Iron-Deficiency
Iron Deficiency Anemia in Twin Pregnancies
All pregnant women with twin pregnancies were given oral iron according to the current recommended dose. Blood routine and ferritin were monitored during pregnancy to understand the therapeutic effect of oral iron on iron…
- Trial name
- NCT04975074
- Testing
- Iron
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
White Matter Injury
Brain White Matter Injury in Late Preterm Infants
At 34 weeks, the brain weight of preterm infants is only 65% that of term infants, and the cortex volume is 53% that of term infants.
- Trial name
- NCT04508517
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Shengjing Hospital
Infectious Diseases in Pneumonia,Nephropyelitis,Angiocholitis or Others, Positive Bacterial Cultures Results of the Medical Records
Bacterial and Antimicrobial Susceptibility Profile and the Prevalence of Different Sites of Infection(BASPP)
Positive results of bacterial culture are analyzed comprehensively in Shengjing Hospital of China Medical University in recent 3 years（between 2015- 2017）
- Trial name
- NCT03333863
- Testing
- descriptive study which reviewed the data of patients hospitalized with positive bacterial cultures
- Where
- China
- Volunteers
- 1,889 people
- Sponsor
- Shengjing Hospital
Gastroesophageal Reflux, Bronchopulmonary Dysplasia
GER Poses a Potential Risk for Late Complications of BPD
Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the…
- Trial name
- NCT03014453
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Positive Node Traced Before Neoadjuvant Chemotherapy (NAC)
To investigate this regression model by injecting and tracing carbon nanoparticles (CNs) into the fusion node prior to NAC in patients with breast cancer.
- Trial name
- NCT03355261
- Testing
- complete remission (CR) group, partial remission (PR) group, stable disease (SD) group
- Where
- 3 sites in China
- Volunteers
- 110 people
- Sponsor
- Shengjing Hospital
Arrhythmia
Efficacy and Safety of Sotalol in Children With Arrhythmia
This study aims to investigate the efficacy and safety of oral sotalol alone or combination with other anti-arrhythmic medicines in the treatment of arrhythmias in children.
- Trial name
- NCT03895411
- Testing
- sotalol, Propafenone, betaloc
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shengjing Hospital
Children AKI Patients
The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury
Acute kidney injury (AKI) is a pervasive clinical event in children.It has been independently associated with prolonged hospital stays, risk of in-hospital death and future progression to chronic kidney disease.
- Trial name
- NCT03892447
- Testing
- Alprostadil, Sodium Ferulate, Dopamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
0.5-14 Year Old Children With Nephroblastoma
Combination Therapy of Anthracyclines for Children With Nephroblastoma
This study aims to estimate the efficacy and side effects of study drugs in children with nephroblastoma who are treated with combination therapy.
- Trial name
- NCT03892330
- Testing
- Vincristine, Oxytetracycline/ Cyclophosphamide, Liposomal doxorubicin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Postoperative Cognitive Dysfunction
Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function
This study compares desflurane with sevoflurane for school-age children in postoperative cognitive function.
- Trial name
- NCT02909413
- Testing
- Desflurane, sevoflurane
- Volunteers
- 600 people
- Sponsor
- Shengjing Hospital