Clinical trials: sponsored by Unity Health Toronto
HIV, Chlamydia
National Rapid TLC: Testing and Linkage to Care
The goal of this cross-sectional study is to learn if the GeneXpert system is a practical system for HIV and STBBI testing in community-based organizations and health clinics.
- Conditions
- HIV, Chlamydia, Gonorrhea, HCV
- Trial name
- NCT07730801
- Testing
- Xpert® HIV-1 Qual XC
- Where
- 2 sites in Canada
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Homelessness, Youth
Transitioning Youth Out of Homelessness 2.0 (TYOH 2.0)
Introduction: This 12-month pilot randomized controlled trial (RCT) built on previous community-engaged work and explored whether portable rent subsidies and an intervention targeting identity capital (purpose, control…
- Trial name
- NCT05781503
- Testing
- Identity Capital Intervention (Coach + Co-designed Leadership Guide), Monthly Rent Subsidies
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Trauma
SWiFT Canada (Study of Whole Blood in Frontline Trauma)
Traumatic injuries affect people of all ages, races, and socioeconomic backgrounds. The Global Burden of Disease study showed that globally in 2019, there were more than 4.4 million deaths due to injury.
- Trial name
- SWiFTCanada (NCT06495294)
- Testing
- Whole Blood, RBC + plasma
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Hereditary Hemorrhagic Telangiectasia
Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research.
- Trial name
- BVMC6203 (NCT01158807)
- Where
- 19 sites in United States, Canada and 1 more
- Volunteers
- 2,272 people
- Sponsor
- Unity Health Toronto
Homelessness, Youth
Transitioning Youth Out of Homelessness 2.5 (TYOH 2.5)
The idea for this study came from the research team's current study called Transitioning Youth Out of Homelessness (TYOH) 2.0, which provides coaching and a leadership guide to youth transitioning out of homelessness.
- Trial name
- NCT06425458
- Testing
- Co-Designed Strengths-Based Leadership Program
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pharmacy, Asthma Management
The Electronic Asthma Management System in Pharmacies
The goal of this study is to assess the effect of an electronic asthma management system in pharmacies (eAMS-Pharm) on asthma control assessment, asthma medication adjustment, asthma action plan delivery, and prompting for…
- Conditions
- Pharmacy, Asthma Management, Asthma, Computerized Decision Support System
- Trial name
- eAMS-Pharm (NCT07038642)
- Testing
- Pharmacy Clinical Decision Support System for Asthma Management
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Mechanical Ventilator Weaning, Respiratory Muscle Training
Muscle Recruitment During Neck Flexion and Inspiratory Muscle Training
Respiratory muscle dysfunction is highly prevalent in patients with prolonged weaning from mechanical ventilation and is strongly associated with weaning failure.
- Trial name
- FLEX (NCT05710432)
- Testing
- Quasi-Isometric Neck Flexion, Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Unity Health Toronto
Respiratory Support
The ACCESSIT Study
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
- Trial name
- ACCESSIT (NCT05207046)
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Autism Spectrum Disorder
Exploring the Efficacy and Usability of the My Autism Passport (MAP).
To address developmental service navigation by families of children with autism spectrum disorder (ASD) an innovative paper-based tracking tool called the Pediatric Developmental Passport (Passport) was created by Dr.
- Trial name
- NCT04259671
- Testing
- My Autism Passport (MAP) Application
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Unity Health Toronto
Point-of-Care Testing, HIV
Ayaangwaamiziwin Initiative: Carefulness and Preparedness
The goal of this clinical trial is to implement a test, treat, and connect intervention approach using HIV and syphilis rapid point-of-care (POC) testing in 3 Canadian Prairie provinces (Alberta, Manitoba, and Saskatchewan)…
- Conditions
- Point-of-Care Testing, HIV, Syphilis
- Trial name
- AI (NCT06893159)
- Testing
- INSTI HIV-1/2 Antibody Test, INSTI Multiplex HIV-1/2 Syphilis Antibody Test, Multiplo Complete Syphilis (TP/nTP) Antibody Test
- Where
- 8 sites in Canada
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Quality of Health Care, HIV/AIDS
Using Electronic Medical Record Data to Improve HIV Primary Care
This cluster randomized control trial examines whether an audit and feedback study improves care of patients living with HIV/AIDS in a family health team setting.
- Conditions
- Quality of Health Care, HIV/AIDS, Electronic Health Records
- Trial name
- NCT04107233
- Testing
- Audit and Feedback
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV, HIV Self-testing
Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction.
When REACH Nexus at MAP Centre for Urban Solutions out of St. Michael's Hospital launched its signature program, I'm Ready in 2021, our goal was to democratize access to free HIV self-testing to reach the undiagnosed in Canada.
- Conditions
- HIV, HIV Self-testing, Harm Reduction, Sexually Transmitted Diseases
- Trial name
- NCT05516069
- Testing
- Our Healthbox (smart vending machine or interactive dispensing system)
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Violence, Assault
Evaluation of Thriving, Substance Use, Mental Health, and Repeat Injury Among Participants in the THRIVE Program
The goal of this observational study is to determine the impact of a hospital-based violence intervention program on a person's capacity to thrive and recurrent intentional injury. The aims of this study are: 1.
- Trial name
- NCT06455943
- Volunteers
- 90 people
- Sponsor
- Unity Health Toronto
Mpox (Monkeypox)
Looking for Asymptomatic Mpox in a Population at High Risk
Mpox is caused by a virus that can be spread through touching the affected skin of someone who has the infection, touching sheets or clothes that has been used by someone with the infection, or breathing in particles of virus…
- Trial name
- LAMP (NCT06353737)
- Where
- Canada
- Volunteers
- 450 people
- Sponsor
- Unity Health Toronto
HIV Infections
Virtual PrEP: Rendering PrEP Delivery More Efficient
Gay, bisexual and other men who have sex with men (GBM) account for over half of new HIV infections in Canada each year, and have a 131-fold higher risk of HIV than other Canadian men.
- Trial name
- VPrEP (NCT05159531)
- Testing
- PrEP, mHealth Model of Care, Standard of Care
- Where
- 5 sites in Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Monkeypox
Mpox Prospective Observational Cohort Study
The goal of this multicentre prospective observational cohort study is to shed light on the following unknowns: 1. The clinical manifestations of Mpox infection since the 2022 outbreak in Canada. 2.
- Trial name
- MPOCS (NCT06291259)
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Unity Health Toronto
Sudden Cardiac Death, Sudden Cardiac Arrest
Canadian Sudden Cardiac Arrest Network
The overall aim of the project is to develop a national registry to accurately measure the burden of Sudden Cardiac Arrest (SCA) among the general Canadian population.
- Trial name
- C-SCAN (NCT03642587)
- Testing
- There is no intervention in this study.
- Where
- 6 sites in Canada
- Volunteers
- 82,054 people
- Sponsor
- Unity Health Toronto
Operating Room Efficiency
Minimizing Peri-operative Time Delays, Maximizing Operating Room Efficiency: A Pilot Study
The primary objective is to prospectively identify Operating Room (OR) time delays from the time the patient who is undergoing total laparoscopic hysterectomy enters the OR to exiting the OR.
- Trial name
- NCT03257384
- Testing
- Black box recording of surgery
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Unity Health Toronto
Uterine Fibroid
Design of an Intra-operative Blood Conservation Pathway at Open Myomectomy
Uterine fibroids are benign uterine masses that can be removed through a surgical procedure called a myomectomy. Myomectomy is often associated with a significant amount of blood loss for the patient.
- Trial name
- NCT03211481
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Pelvic Inflammatory Disease
Rate of Pelvic Inflammatory Disease at St. Michael's Hospital
A retrospective review of women who came through the ER at SMH with a pelvic inflammatory disease (PID) or tubo-ovarian abscess (TOA) between 1995-2005.
- Trial name
- NCT00783419
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Unity Health Toronto