Find a clinical trial
Myocardial Bridging, Coronary Atherosclerosis
Coronary Myocardial Bridge and Coronary Plaques on MDCT
Myocardial bridging is a condition in which a segment of a coronary artery passes through the heart muscle instead of running on its surface.
- Trial name
- NCT07916272
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anxiety Disorder of Adolescence
Parent-Based Treatment for Adolescent Anxiety
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions).
- Trial name
- NCT07219992
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE), Parent Educational Support (PES)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Yale University
Left Ventricular Ejection Fraction, Heart Failure (HF)
REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)
Primary Objective - To determine if implantation of a permanent CRT pacing device (with LB-CRT, or conventional BiV-CRT with a coronary sinus LV lead) can improve electromechanical function, HF symptoms, and natriuretic peptide…
- Conditions
- Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
- Trial name
- REINVENT (NCT05652218)
- Testing
- LB-CRT, BIV-CRT
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Inova Health Care Services
Acute Leukemia
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D[s]) of bleximenib in phase 1 Part 1 (Dose Escalation) and to determine the safety and tolerability at RP2D in Phase 1 Part 2 (Dose expansion).
- Trial name
- cAMeLot-1 (NCT04811560)
- Testing
- Bleximenib
- Where
- 102 sites in United States, Australia and 11 more
- Volunteers
- 420 people
- Sponsor
- Janssen Research & Development, LLC
Non-Hodgkin Lymphoma, Hodgkin Lymphoma
Auto Stem Cell Transplant for Lymphoma Patients
This is a phase II study of autologous transplant for patients with Hodgkin (HL) and non-Hodgkin lymphomas (NHL) including those who are HIV positive.
- Trial name
- NCT03125642
- Testing
- Etoposide, BCNU, AraC
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Tumor-induced Osteomalacia (TIO)
Tumor-induced Osteomalacia Disease Monitoring Program
The objectives of this observational study are to assess the long-term safety and long-term effectiveness of burosumab in patients with TIO who are being treated with burosumab as prescribed by their physician and to monitor the…
- Trial name
- NCT04783428
- Testing
- No intervention
- Where
- 6 sites in United States, Argentina
- Volunteers
- 23 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Depression, Anxiety
Low Intensity Family Support for Refugees in an LMIC
The rapidly growing scale of humanitarian crises requires new response capabilities geared towards addressing populations with prolonged high vulnerability to mental health consequences and little to no access to mental health…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT03978533
- Testing
- Family Support Group
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Atopic Dermatitis, Atopic Dermatitis (AD)
Roflumilast Cream 0.3% for Moderate to Severe Atopic Dermatitis
This Phase 3 study is designed to evaluate the efficacy and safety of once-daily roflumilast cream 0.3% in children, adolescents, and adults with moderate to severe atopic dermatitis.
- Conditions
- Atopic Dermatitis, Atopic Dermatitis (AD), Atopic Dermatitis (Eczema)
- Trial name
- INTEGUMENT 3 (NCT07916480)
- Testing
- Roflumilast Cream 0.3%, Vehicle Cream
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Thalassemia, Beta, Thalassemia Major
Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells
This is a single-arm, open, single-injection exploratory clinical study with two transfusion-dependent β thalassemia (β-TDT) participants planned to enroll.
- Trial name
- NCT06041620
- Testing
- VGB-Ex01
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Hair Loss
Natural History and Pathogenesis of Alopecia in Children and Adults
Background: Alopecia is the loss of hair or lack of hair growth. It is often related to an immune disorder that disrupts the growth of hair. Hair loss can affect a person s physical and mental health.
- Trial name
- NCT05502796
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Arrhythmia, Bradycardia
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival…
- Conditions
- Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
- Trial name
- PPR (NCT00271180)
- Testing
- Device
- Where
- 338 sites in United States, Australia and 33 more
- Volunteers
- 20,000 people
- Sponsor
- Medtronic
Osteopenia
Optimal Meals to Reduce Bone Resorption in Women With Osteopenia
The goal of this clinical trial is to investigate whether different types of small meals can help reduce bone loss in postmenopausal women with osteopenia, a condition where bone density is lower than normal and may lead to…
- Trial name
- NCT07056322
- Testing
- 200 ml dairy, 100 ml milk, 100 g banana
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Hiv
Testing a Novel Data-to-Suppression (D2S) Intervention Strategy in the Ryan White HIV/AIDS Program
The Ryan White HIV/AIDS Program (RWHAP) for low-income people with HIV (PWH) is a key resource for reducing HIV health disparities and scaling up evidence-based interventions.
- Trial name
- D2S (NCT05140421)
- Testing
- Data to Suppression (D2S), Usual practice
- Where
- 27 sites in United States
- Volunteers
- 1,494 people
- Sponsor
- City University of New York
Primary Ciliary Dyskinesia (PCD)
Comparison of Individuals With Primary Ciliary Dyskinesia and Healthy Controls
To date, the literature has not yet elucidated the status of malnutrition and sarcopenia in children and adolescents with PCD compared to healthy controls.
- Trial name
- NCT07740551
- Testing
- Physical Evaluations in Children with Primary Ciliary Dyskinesia, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis
Buprenorphine for the Management of Pain in Children With Sickle Cell Disease
The goal of this clinical trial is to learn whether a single dose of buccal buprenorphine (BELBUCA) is safe when used in place and/or with full agonist opioids that would otherwise be started during a sickle cell pain crisis…
- Conditions
- Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children
- Trial name
- NCT07799571
- Testing
- Buprenorphine Buccal Film [Belbuca]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Natasha Archer
Hyperlipidemia, Normal
Comparative Analysis of Chamomile Tea (Matricaria Chamomilla) and Green Tea (Camellia Sinensis) Against Hyperlipidemia
Present study was conducted to compare the efficacy of green tea (Camellia sinensis) and chamomile tea (Matricaria chamomilla), administered individually, as a combined intervention, and as a sequential (morning/evening) regimen…
- Trial name
- NCT07907081
- Testing
- Chamomile tea (Matricaria chamomilla), Green tea (Camellia sinensis)
- Where
- Pakistan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Iahtisham-Ul-Haq
Simulation Training, Nursing Education
SELF-ASSESSMENT AND KNOWLEDGE LEVEL OF NURSING STUDENTS' PATIENT SAFETY COMPETENCY
Patient safety aims to reduce risks during healthcare delivery, prevent avoidable harm, and minimize the consequences of adverse events.
- Conditions
- Simulation Training, Nursing Education, Patient Safety
- Trial name
- Simulation (NCT07915999)
- Testing
- video-based simulation
- Volunteers
- 86 people
- Sponsor
- Bartın Unıversity
Cancer
Positioning in RT - Supine vs. Upright
This is a single-center, non-therapeutic prospective pilot cohort study evaluating patient-reported comfort levels between upright and supine positioning in patients receiving radiation therapy across all age groups using a…
- Trial name
- Position in RT (NCT07765069)
- Testing
- Upright positioning chair
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University Health Network, Toronto
Sleep Deprivation
The Function of Biphasic Sleep in Infants
This study is designed to investigate developmental changes in naps and nap function on memory from 9 to 15 months of age. Memory is measured by a task in which the experimenter interacts with a toy and the measure of memory is…
- Trial name
- NCT06399939
- Testing
- Nap, Wake
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Metabolic Disease, Obesity
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Background: Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels.
- Conditions
- Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy
- Trial name
- NCT01143454
- Testing
- NSR IDE-MRI: Research pulse sequences
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.