Find a clinical trial
Graft-Versus-Host Disease, GVHD
A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
The purpose of this study is to find out whether photobiomodulation/PBM therapy using the Thor LX2.3 therapy system is a safe and effective treatment for oral Graft-Versus-Host Disease/GVHD.
- Conditions
- Graft-Versus-Host Disease, GVHD, Undefined
- Trial name
- NCT05675930
- Testing
- Photobiomodulation Therapy
- Where
- 9 sites in United States
- Volunteers
- 44 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Amblyopia
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Participants eligible for the study will be randomly allocated (1:1:1) to receive either Luminopia dichoptic treatment while wearing optical correction if needed, Vivid Vision dichoptic treatment while wearing optical correction…
- Trial name
- ATS24 (NCT06524882)
- Testing
- Vivid Vision, Luminopia, Optical Correction
- Where
- 58 sites in United States
- Volunteers
- 252 people
- Sponsor
- Jaeb Center for Health Research
Brain Injuries
Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)
To study the feasibility of the various model of ART rental service for home use, prescribed and supervised by experienced rehabilitation professionals and supported by tech partners, and its efficacy in improving function in…
- Trial name
- R@H (NCT07904624)
- Testing
- ART
- Where
- 3 sites in Singapore
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Liver Transplantation, Auxiliary Liver Transplantation
Rejection After Auxiliary Partial Orthotopic Liver Transplantation: An Exploratory Comparison by Native-Liver Cirrhosis Status
This retrospective single-center cohort study aims to investigate the association between native-liver cirrhosis status and post-transplant outcomes in recipients undergoing auxiliary partial orthotopic liver transplantation…
- Trial name
- NCT07275008
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Zhi-Jun Zhu
Hemophilia B
Lentiviral FIX Gene Therapy
This study is a Phase I trial using an advanced lentiviral vector to deliver a functional gene for human clotting factor IX into patients with hemophilia B, to evaluate the safety and efficacy of infusion of lentiviral gene…
- Trial name
- NCT03961243
- Testing
- YUVA-GT-F901
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
High-altitude Pulmonary Edema
High-flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy in Children High-altitude Pulmonary Edema
This study aims to evaluate whether High-flow Nasal Cannula Oxygen Therapy (HFNC) provides superior respiratory support compared to Conventional Oxygen Therapy (COT) in children with High-Altitude Pulmonary Edema (HAPE).
- Trial name
- NCT07910357
- Testing
- High-flow Nasal Cannula Oxygen Therapy (HFNC)
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Ye Fan
Probiotic in Preterm Babies Use & Abuse, Uses
Probiotics in Preterm Babies Use & Abuse
This is observational study conducted at sohag univeristy hospital to asses the clinical presentation, To evaluate all aspect of using probiotics in preterm(efficacy, lowering of sepsis, lowering necrotizing enterocolitis…
- Conditions
- Probiotic in Preterm Babies Use & Abuse, Uses, Side Effect
- Trial name
- Pro-pre-bab (NCT07910344)
- Testing
- Probiotic
- Volunteers
- 200 people
- Sponsor
- Norhan Mohamed Abdelrady
Tuberculosis
Re-evaluating the Duration in Children of TB Treatment
Current tuberculosis (TB) treatment is effective (works well), but it takes a long time to cure TB. This study will evaluate if TB treatment with a higher dose of rifampicin, one of the TB medicines, and shorter TB treatment…
- Trial name
- REDUCE TB (NCT07656012)
- Testing
- Rifampicin, Isoniazid, Pyrazinamide
- Where
- Peru
- Volunteers
- 230 people
- Sponsor
- University of Wisconsin, Madison
Cardiac Disease
BoStOn SCientific Rhythm MAnagemenT REgiStry
SOCRATES is part of Boston Scientific's (BSC) Post-market surveillance system. The implementation of such systems is mandatory per local regulations such as the Regulation '(EU) 2017/745 of the European Parliament and of the…
- Trial name
- SOCRATES (NCT04823663)
- Testing
- Implant, Electrophysiologic procedure
- Where
- 26 sites in Belgium, Canada and 8 more
- Volunteers
- 12,500 people
- Sponsor
- Boston Scientific Corporation
PreDiabetes, Diet, Healthy
Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes
This study will address the following aims: Aim 1 (primary): Conduct a pilot RCT to evaluate the feasibility, acceptability, enrollment, and retention rates of adult-offspring pairs or adult-spouse/significant other pairs after a…
- Conditions
- PreDiabetes, Diet, Healthy, Nutritional and Metabolic Diseases
- Trial name
- NCT06482944
- Testing
- Whole Foods for Families
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
Systemic Lupus Erythematosus
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of moderate to severe disease…
- Trial name
- PHOENYCS FLY (NCT06617325)
- Testing
- DZP
- Where
- 245 sites in United States, Argentina and 21 more
- Volunteers
- 450 people
- Sponsor
- UCB Biopharma SRL
Pathogen Infection, EBV Infection
Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections
Epstein Barr Virus (EBV) or Cytomegalovirus (CMV) infection results in significant morbidity and mortality in hematopoietic stem cell transplantation (HSCT) patients.
- Conditions
- Pathogen Infection, EBV Infection, CMV Infection, Adenovirus Infection
- Trial name
- NCT03159364
- Testing
- pathogen-specific CTLs
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Chronic Pain, Body Mass Index >=85th Percentile
Probiotics for Inflammation in Pediatric Chronic Pain
To examine benefits of a probiotic for youth with chronic pain and a Body Mass Index >=85th percentile.
- Trial name
- NCT05141890
- Testing
- Lactobacillus Plantarum
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Medical College of Wisconsin
Amblyopia
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days…
- Trial name
- ATS23 (NCT06380517)
- Testing
- Luminopia, Eye Patch
- Where
- 73 sites in United States
- Volunteers
- 238 people
- Sponsor
- Jaeb Center for Health Research
B Precursor Acute Lymphoblastic Leukemia, Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)
The primary objective of this study is to evaluate the efficacy of blinatumomab.
- Trial name
- NCT06054113
- Testing
- Blinatumomab
- Where
- 7 sites in China
- Volunteers
- 18 people
- Sponsor
- Amgen
Spinal Muscular Atrophy (SMA)
An International Federated Model for Wearable-derived Remote Longitudinal Motor Monitoring in Young Children With Spinal Muscular Atrophy Compared With Healthy Controls: Active-NBS Study (UK)
Active-NBS is a study to evaluate the muscle development of patients with spinal muscular atrophy (SMA) who are diagnosed at birth. Medicines have become available in the last decade, and many patients are treated very early.
- Trial name
- Active-NBS UK (NCT07543003)
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Myopia
A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control
To date, randomized trials of low-concentration atropine eyedrops and specially designed spectacle lenses to slow the progression of myopia are limited in number and results are inconsistent in non-Asian children.
- Trial name
- NCT07095894
- Testing
- Atropine, Spectacles with HAL
- Where
- 18 sites in United States
- Volunteers
- 348 people
- Sponsor
- Jaeb Center for Health Research
Prematurity, Delayed Passage of Meconium
Rectal Administration of Mother's Own Milk and Growth in Preterm Infants
This retrospective observational cohort study evaluated whether rectal administration of mother's own milk was associated with feeding progression and growth in preterm infants.
- Conditions
- Prematurity, Delayed Passage of Meconium, Feeding Intolerance
- Trial name
- NCT07908966
- Testing
- Rectal Administration of Mother's Own Milk
- Where
- Azerbaijan
- Volunteers
- 50 people
- Sponsor
- Azerbaijan Medical University
Amputation Stump, Burn Injury
Hypertrophic Scar Prosthetic Pressure in Burn Amputee
Amputation following burn injury is rare but complex, affecting predominantly younger individuals with extensive burns, particularly electrical injuries, and often resulting in residual limbs characterized by scarring…
- Conditions
- Amputation Stump, Burn Injury, Pressure Distribution, Pressure Injuries
- Trial name
- NCT07850557
- Testing
- Skin assessment of prothesis interface and control area, Interface pressure
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Solid Tumor
GD2/PSMA Bi-specific CAR-T Cell Therapy
The purpose of this clinical trial is to assess the feasibility, safety and efficacy of anti-GD2/PSMA bi-specific CAR-T cell therapy in patients with GD2 and PSMA positive tumor.
- Trial name
- NCT05437315
- Testing
- bi-4SCAR GD2/PSMA T cells
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
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