Clinical trials: completed
Obesity
Whole Body Vibration Effects on Energy Expenditure in Obese Adolescents
The main aim of the present study is to evaluate in a group of adolescents with obesity, hospitalized for a period of integrated metabolic rehabilitation (calorie restriction, aerobic physical activity, psychological counseling…
- Trial name
- VIBRAREEOB (NCT06800872)
- Testing
- Multidisciplinary metabolic rehabilitation, Multidisciplinary metabolic rehabilitation + training with WBVE
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Istituto Auxologico Italiano
Pediatric Steroid-Induced Ocular Hypertension and Glaucoma
Management Pediatric Steroid Induced Glaucoma
Purpose: To compare the efficacy and safety of ab externo circumferential suture trabeculotomy (ACST) and non-penetrating deep sclerectomy (NPDS) in children with steroid-induced ocular hypertension or glaucoma over 24 months.
- Trial name
- NCT04673201
- Testing
- Group B: Non-Penetrating Deep Sclerectomy (NPDS), Group A: Ab Externo Circumferential Suture Trabeculotomy (ACST)
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Diffuse Intrinsic Pontine Glioma, PNET
Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
This study will analyze the effects of radiation given to children who have tumors of the central nervous system (CNS). Researchers want to learn more about changes in the quality of life that patients may experience as a result…
- Conditions
- Diffuse Intrinsic Pontine Glioma, PNET, Ependymoma, Germinoma
- Trial name
- NCT01445288
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- National Cancer Institute (NCI)
Neonate, Circumcision
Dilemma of Neonatal Circumcision in Egypt
The study aims to compare wound healing, wound healing complications, cosmetic outcome, and level of parental satisfaction amongst four techniques of neonatal circumcision.
- Trial name
- NCT07076992
- Testing
- Circumcision by Plastibell, Circumcision by Gomco, bone cutter circumcision with suture hemostasis (BCS),
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Plaque Psoriasis
Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis.
- Trial name
- NCT05172726
- Testing
- tapinarof cream, 1%
- Where
- 19 sites in United States, Canada
- Volunteers
- 58 people
- Sponsor
- Organon and Co
Maturation Level, Football Players
Biological Maturation, Athletic Performance, and Injury Risk in Adolescent Male Soccer Players
This study aims to investigate the relationship between biological maturation, athletic performance, and injury risk in adolescent male soccer players.
- Conditions
- Maturation Level, Football Players, Injuries; Muscle, Nontraumatic, Prevention
- Trial name
- NCT07920146
- Testing
- Anthropometric and Performance Assessment.
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Pediatric, Elective
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. IV Dexmedetomidine Improves LMA Insertion Success and Decreases Coughing, While IV Lidocaine Decreases Postoperative Cough.
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. LMA may help in reducing postoperative pulmonary complications.
- Conditions
- Pediatric, Elective, Surgery in Early Childhood
- Trial name
- DEX LMA (NCT07562308)
- Testing
- Dexamedomedine, Lidocaine (drug)
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Arm
The Effect of Dexamethasone Administration Route in Pediatric Brachial Plexus Block
This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain and inflammatory response in pediatric patients undergoing hand/wrist surgery.
- Trial name
- NCT07061678
- Testing
- perineural dexamethasone, intravenous dexamethasone, 0.2ml/kg 0.2% ropivacaine
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Autoimmune/Connective Tissue Diseases, Idiopathic Inflammatory Myopathies
Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases
This study will define the major genetic risk and protective factors for idiopathic inflammatory myopathies (IIM), a group of immune disorders affecting connective tissues such as muscles.
- Conditions
- Autoimmune/Connective Tissue Diseases, Idiopathic Inflammatory Myopathies, Polymyositis, Dermatomyositis
- Trial name
- NCT00341679
- Where
- United States
- Volunteers
- 719 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
HIV
PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)
Background: There are many people living with human immunodeficiency virus (HIV) infection in Liberia. Most experts consider HIV an epidemic there.
- Trial name
- NCT03733093
- Where
- 4 sites in Liberia
- Volunteers
- 1,377 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Physical Activity, Mobile Application
HopeMove App in Pediatric Cancer Patients
This pilot feasibility study aims to assess the acceptability, usability, safety, and initial effects of the HopeMove mobile health app on fatigue in adolescents aged 13 to 18 years undergoing hematology-oncology treatment.
- Trial name
- NCT07274358
- Testing
- HopeMove Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Koç University
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Multi-observational Study for the Early Identification of Autism Spectrum Disorder (ASD) and Other Neurodevelopmental Disorders (NDD) in At-risk Populations
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects about 78 million people worldwide. Its prevalence and degree of impact on individuals and families place it among disorders of global importance.
- Trial name
- BABY@NET (NCT06915805)
- Where
- 5 sites in Italy
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità
Pediatric Surgical Procedures, Adult Surgical Procedures
A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures
The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical…
- Conditions
- Pediatric Surgical Procedures, Adult Surgical Procedures, Adult Gynecological Procedures, Adult Urological Procedures
- Trial name
- NCT06608485
- Testing
- HARMONIC 700 Shears
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 173 people
- Sponsor
- Ethicon Endo-Surgery
Cardiometabolic Risk Factors
Effect of Vitamin D on Cardiometabolic Risk in Chinese Adolescents
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with vitamin D deficiency and normal-BMI or overweight/obesity.
- Trial name
- NCT07053657
- Testing
- Dietary Supplement: Vitamin D3
- Where
- 2 sites in China
- Volunteers
- 306 people
- Sponsor
- Anhui Medical University
Cockayne Syndrome, Skin Neoplasms
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Four rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), the XP/CS complex and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility.
- Conditions
- Cockayne Syndrome, Skin Neoplasms, Xeroderma Pigmentosum, Trichothiodystrophy Syndromes
- Trial name
- NCT00001813
- Where
- United States
- Volunteers
- 709 people
- Sponsor
- National Cancer Institute (NCI)
Language Impairment, Autism
Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment
This study will pilot a newly developed Syntactic-Semantic Visual Configuration Intervention (SSVCI) designed to help Urdu-speaking children with language impairment improve their ability to understand and produce phrases and…
- Conditions
- Language Impairment, Autism, Hearing Impaired Children, Down Syndrome
- Trial name
- NCT07786545
- Testing
- Syntactic-Semantic Visual Configuration Intervention (SSVCI)
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Mild Traumatic Brain Injury
Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test
This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in…
- Trial name
- NCT06276660
- Testing
- BCTT, Dynamic ExIT
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pittsburgh
Adolescence, Mindfulness
The Effectiveness of a Mindfulness Based Program on Short- Form Video Addiction in Adolescents
The purpose of this study is to evaluate the effectiveness of a mindfulness-based program in reducing short form video addiction among adolescents.
- Conditions
- Adolescence, Mindfulness, Addiction, Mental Health
- Trial name
- NCT07374666
- Testing
- Mindfulness Based Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Istanbul University - Cerrahpasa
GERD
The Prospective Observational Study Evaluating the Clinical Profile and Correlation of Subjective and Objective Parameters of GERD in a Tertiary Care Hospital : An Indian Perspective
This prospective, single-center study at AIG Hospitals, Hyderabad, aims to establish normal 24-hour ambulatory esophageal pH-impedance values, including acid exposure time (AET), in 50 healthy Indian adults.
- Trial name
- NCT07919522
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Prematurity, Delayed Passage of Meconium
Rectal Administration of Mother's Own Milk and Growth in Preterm Infants
This retrospective observational cohort study evaluated whether rectal administration of mother's own milk was associated with feeding progression and growth in preterm infants.
- Conditions
- Prematurity, Delayed Passage of Meconium, Feeding Intolerance
- Trial name
- NCT07908966
- Testing
- Rectal Administration of Mother's Own Milk
- Where
- Azerbaijan
- Volunteers
- 50 people
- Sponsor
- Azerbaijan Medical University
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